Human Placental Explants | List of Frontiers open access articles

Original Research

Published on 06 Nov 2020

Trypanosoma cruzi and Toxoplasma gondii Induce a Differential MicroRNA Profile in Human Placental Explants

in Microbial Immunology

Lisvaneth Medina
Christian Castillo
Ana Liempi
Jesús Guerrero-Muñoz
Maura Rojas-Pirela
Juan Diego Maya
Humberto Prieto
Ulrike Kemmerling

Frontiers in Immunology

doi 10.3389/fimmu.2020.595250

7,035 views
24 citations

Original Research

Published on 13 Jan 2026

Dulaglutide and pregnancy: a comprehensive safety assessment using the ex vivo placenta perfusion and in vitro models

in Obstetric and Pediatric Pharmacology

Sabrina Kuoni
Sara Caviglia
Alexandra Dolder
Joanna Gawinecka
Nicole Ochsenbein-Kölble
Ana Paula Simões-Wüst

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1765815

907 views
1 citation

Original Research

Published on 20 Nov 2024

Polystyrene microplastics exposition on human placental explants induces time-dependent cytotoxicity, oxidative stress and metabolic alterations

in Developmental Endocrinology

Ashelley Kettyllem Alves de Sousa
Keyla Silva Nobre Pires
Isadora Hart Cavalcante
Iasmin Cristina Lira Cavalcante
Julia Domingues Santos
Maiara Ingrid Cavalcante Queiroz
Ana Catarina Rezende Leite
Alessandre Carmo Crispim
Edmilson Rodrigues da Rocha Junior
Thiago Mendonça Aquino

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1481014

7,457 views
20 citations

Original Research

Published on 14 Oct 2024

Trypanosoma cruzi-derived exovesicles contribute to parasite infection, tissue damage, and apoptotic cell death during ex vivo infection of human placental explants

in Parasite and Host

Alejandro Fernández-Moya
Bielca Oviedo
Ana Liempi
Jesús Guerrero-Muñoz
Cristian Rivas
Rocío Arregui
Sebastian Araneda
Alberto Cornet-Gomez
Juan Diego Maya
Marioly Müller

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2024.1437339

3,709 views
6 citations

Original Research

Published on 11 Nov 2020

Amnion-Derived Mesenchymal Stem Cell Exosomes-Mediated Autophagy Promotes the Survival of Trophoblasts Under Hypoxia Through mTOR Pathway by the Downregulation of EZH2

in Stem Cell Research

Yijing Chu
Weiping Chen
Wei Peng
Yong Liu
Lin Xu
Jianxin Zuo
Jun Zhou
Yan Zhang
Ning Zhang
Jing Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2020.545852

7,438 views
42 citations

Original Research

Published on 08 Jul 2020

Differential Role of Smad2 and Smad3 in the Acquisition of an Endovascular Trophoblast-Like Phenotype and Preeclampsia

in Experimental Endocrinology

Jelena Brkić
Caroline Dunk
Yanan Shan
Jacob Anderson O'Brien
Phetcharawan Lye
Sheza Qayyum
Peifeng Yang
Stephen G. Matthews
Stephen J. Lye
Chun Peng

Frontiers in Endocrinology

doi 10.3389/fendo.2020.00436

7,867 views
24 citations

Original Research

Published on 03 Dec 2025

Novel drug candidates targeting Toxoplasma gondii in maternal–fetal interface models

in Experimental Pharmacology and Drug Discovery

Rafael Martins de Oliveira
Natália Carine Lima dos Santos
Marcos Paulo Oliveira Almeida
Joed Pires De Lima Júnior
Guilherme De Souza
Matheus Carvalho Barbosa
Guilherme Vieira Faria
Marina Paschoalino
Rosiane Nascimento Alves
Angelica Oliveira Gomes

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1673462

1,685 views

Articles

Trypanosoma cruzi and Toxoplasma gondii Induce a Differential MicroRNA Profile in Human Placental Explants

Dulaglutide and pregnancy: a comprehensive safety assessment using the ex vivo placenta perfusion and in vitro models

Polystyrene microplastics exposition on human placental explants induces time-dependent cytotoxicity, oxidative stress and metabolic alterations

Trypanosoma cruzi-derived exovesicles contribute to parasite infection, tissue damage, and apoptotic cell death during ex vivo infection of human placental explants

Amnion-Derived Mesenchymal Stem Cell Exosomes-Mediated Autophagy Promotes the Survival of Trophoblasts Under Hypoxia Through mTOR Pathway by the Downregulation of EZH2

Differential Role of Smad2 and Smad3 in the Acquisition of an Endovascular Trophoblast-Like Phenotype and Preeclampsia

Novel drug candidates targeting Toxoplasma gondii in maternal–fetal interface models