Hypoxia Inducible Factor 2 | List of Frontiers open access articles

Systematic Review

Published on 11 Jun 2018

Prognostic Role of Hypoxia-Inducible Factor-2α Tumor Cell Expression in Cancer Patients: A Meta-Analysis

in Molecular and Cellular Oncology

Eloy Moreno Roig
Ala Yaromina
Ruud Houben
Arjan J. Groot
Ludwig Dubois
Marc Vooijs

Frontiers in Oncology

doi 10.3389/fonc.2018.00224

8,346 views
53 citations

Original Research

Published on 12 Jan 2022

SIPA1 Enhances Aerobic Glycolysis Through HIF-2α Pathway to Promote Breast Cancer Metastasis

in Molecular and Cellular Oncology

Chenguang Yao
Jun Weng
Lingyun Feng
Wanjun Zhang
Yan Xu
Peijing Zhang
Yoshimasa Tanaka
Li Su

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.779169

5,133 views
20 citations

Original Research

Published on 26 Jul 2022

Decreased plasma levels of PDGF-BB, VEGF-A, and HIF-2α in preterm infants after ibuprofen treatment

in Neonatology

Xuemei Huang
Dongshan Han
Yanfei Wei
Bingchun Lin
Dingyuan Zeng
Yu Zhang
Ba Wei
Zhifeng Huang
Xueyu Chen
Chuanzhong Yang

Frontiers in Pediatrics

doi 10.3389/fped.2022.919879

4,340 views
11 citations

Mini Review

Published on 10 Dec 2025

HIF-2α inhibitors in clear cell renal cell carcinoma: a clinical pharmacy perspective on lipid metabolism, therapeutic management, and resistance strategies

in Nephrology

Dongmei Chen
Chunwang Hua

Frontiers in Medicine

doi 10.3389/fmed.2025.1735808

1,139 views
1 citation

Review

Published on 09 Feb 2026

Hypoxia-inducible factors link inflammation and lipid metabolism in atherosclerotic macrophages

in Atherosclerosis and Vascular Medicine

Kyu Seong Park
Yu Jin Ko
Jae-Hoon Choi

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1765661

425 views

Original Research

Published on 08 Jul 2022

SerpinB3 as a Pro-Inflammatory Mediator in the Progression of Experimental Non-Alcoholic Fatty Liver Disease

in Inflammation

Erica Novo
Andrea Cappon
Gianmarco Villano
Santina Quarta
Stefania Cannito
Claudia Bocca
Cristian Turato
Maria Guido
Marina Maggiora
Francesca Protopapa

Frontiers in Immunology

doi 10.3389/fimmu.2022.910526

8,424 views
21 citations

Original Research

Published on 03 Mar 2026

T cell-specific HIF-2α attenuates colitis by antagonizing notch-driven Th2 differentiations

in T Cell Biology

Ting Gao
Liangfeng Gao
Hui Zhang
Zaizhi Liu
Qing Zhu
Chunyan Wang
Song Zhang
Nan Feng

Frontiers in Immunology

doi 10.3389/fimmu.2026.1755068

Review

Published on 23 Feb 2026

Current research on the HIF-2α-EPO–Hb axis in hypoxic environments: from molecular mechanisms to clinical

in Hematology

Qiaochu Zheng
Yinglan Li
Jimei Li

Frontiers in Medicine

doi 10.3389/fmed.2026.1780669

304 views

Original Research

Published on 28 Feb 2024

Hypoxia-inducible factor-2α promotes fibrosis in non-alcoholic fatty liver disease by enhancing glutamine catabolism and inhibiting yes-associated protein phosphorylation in hepatic stellate cells

in Obesity

Ranran Yan
Hao Cai
Xiaofeng Zhou
Guodan Bao
Zhenzhong Bai
Ri-li Ge

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1344971

6,883 views
16 citations

Review

Published on 05 Oct 2023

The connection between tricarboxylic acid cycle enzyme mutations and pseudohypoxic signaling in pheochromocytoma and paraganglioma

in Neuroendocrine Science

Yuxiong Wang
Bin Liu
Faping Li
Yanghe Zhang
Xin Gao
Yishu Wang
Honglan Zhou

Frontiers in Endocrinology

doi 10.3389/fendo.2023.1274239

8,856 views
17 citations

Original Research

Published on 19 May 2025

Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Zhiyi Wang
Yujia Shi
Yachen Yang
Bangdong Gong
Jianmin Xie

Frontiers in Immunology

doi 10.3389/fimmu.2025.1577590

3,810 views

Original Research

Published on 10 May 2017

Double Knockdown of PHD1 and Keap1 Attenuated Hypoxia-Induced Injuries in Hepatocytes

in Integrative Physiology

Jing Liu
Yiping Li
Lei Liu
Zhi Wang
Chuanbing Shi
Zhengyuan Cheng
Xiaoyi Zhang
Fengan Ding
Ping Sheng Chen

Frontiers in Physiology

doi 10.3389/fphys.2017.00291

6,324 views
15 citations

Articles

Prognostic Role of Hypoxia-Inducible Factor-2α Tumor Cell Expression in Cancer Patients: A Meta-Analysis

SIPA1 Enhances Aerobic Glycolysis Through HIF-2α Pathway to Promote Breast Cancer Metastasis

Decreased plasma levels of PDGF-BB, VEGF-A, and HIF-2α in preterm infants after ibuprofen treatment

HIF-2α inhibitors in clear cell renal cell carcinoma: a clinical pharmacy perspective on lipid metabolism, therapeutic management, and resistance strategies

Hypoxia-inducible factors link inflammation and lipid metabolism in atherosclerotic macrophages

SerpinB3 as a Pro-Inflammatory Mediator in the Progression of Experimental Non-Alcoholic Fatty Liver Disease

T cell-specific HIF-2α attenuates colitis by antagonizing notch-driven Th2 differentiations

Current research on the HIF-2α-EPO–Hb axis in hypoxic environments: from molecular mechanisms to clinical

Hypoxia-inducible factor-2α promotes fibrosis in non-alcoholic fatty liver disease by enhancing glutamine catabolism and inhibiting yes-associated protein phosphorylation in hepatic stellate cells

The connection between tricarboxylic acid cycle enzyme mutations and pseudohypoxic signaling in pheochromocytoma and paraganglioma

Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis

Double Knockdown of PHD1 and Keap1 Attenuated Hypoxia-Induced Injuries in Hepatocytes