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5 articles related to "In Vitro Adme"

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Articles

Original Research

Published on 18 Feb 2019

An in vitro ADME and in vivo Pharmacokinetic Study of Novel TB-Active Decoquinate Derivatives

in Experimental Pharmacology and Drug Discovery

Lloyd Tanner
Richard K. Haynes
Lubbe Wiesner

Frontiers in Pharmacology

doi 10.3389/fphar.2019.00120

16,016 views
19 citations

Original Research

Published on 03 Oct 2024

Development and validation of PBPK models for genistein and daidzein for use in a next-generation risk assessment

in Predictive Toxicology

A. Najjar
D. Lange
C. Géniès
J. Kuehnl
A. Zifle
C. Jacques
E. Fabian
N. Hewitt
A. Schepky

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1421650

4,231 views
7 citations

Original Research

Published on 16 Aug 2022

Preclinical Pharmacokinetics and In Vitro Properties of GS-441524, a Potential Oral Drug Candidate for COVID-19 Treatment

in Drug Metabolism and Transport

Amy Q. Wang
Natalie R. Hagen
Elias C. Padilha
Mengbi Yang
Pranav Shah
Catherine Z. Chen
Wenwei Huang
Pramod Terse
Philip Sanderson
Wei Zheng

Frontiers in Pharmacology

doi 10.3389/fphar.2022.918083

7,949 views
28 citations

Original Research

Published on 09 Aug 2021

Comparison of Pinoresinol and its Diglucoside on their ADME Properties and Vasorelaxant Effects on Phenylephrine-Induced Model

in Experimental Pharmacology and Drug Discovery

Yiqiong Pu
Yiqing Cai
Qi Zhang
Tianling Hou
Teng Zhang
Tong Zhang
Bing Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.695530

6,093 views
9 citations

Original Research

Published on 04 Jan 2022

Use of Physiologically-Based Kinetics Modelling to Reliably Predict Internal Concentrations of the UV Filter, Homosalate, After Repeated Oral and Topical Application

in Predictive Toxicology

Abdulkarim Najjar
Andreas Schepky
Christopher-Tilman Krueger
Matthew Dent
Sophie Cable
Hequn Li
Sebastien Grégoire
Laurene Roussel
Audrey Noel-Voisin
Nicola J. Hewitt

Frontiers in Pharmacology

doi 10.3389/fphar.2021.802514

7,990 views
14 citations