Skip to main content

4 articles related to "Inducible Caspase 9"

No matches to your query could be found. Try another search term.
No matches to your query could be found. Try another search term.
No matches to your query could be found. Try another search term.
No matches to your query could be found. Try another search term.
No matches to your query could be found. Try another search term.

Articles

Original Research

Published on 06 Oct 2021

Depletion of T cells via Inducible Caspase 9 Increases Safety of Adoptive T-Cell Therapy Against Chronic Hepatitis B

in Viral Immunology

Alexandre Klopp
Sophia Schreiber
Anna D. Kosinska
Martin Pulé
Ulrike Protzer
Karin Wisskirchen

Frontiers in Immunology

doi 10.3389/fimmu.2021.734246

7,367 views
22 citations

Original Research

Published on 19 Oct 2021

Inclusion of the Inducible Caspase 9 Suicide Gene in CAR Construct Increases Safety of CAR.CD19 T Cell Therapy in B-Cell Malignancies

in Cancer Immunity and Immunotherapy

Marika Guercio
Simona Manni
Iolanda Boffa
Simona Caruso
Stefano Di Cecca
Matilde Sinibaldi
Zeinab Abbaszadeh
Antonio Camera
Roselia Ciccone
Vinicia Assunta Polito

Frontiers in Immunology

doi 10.3389/fimmu.2021.755639

11,023 views
65 citations

Mini Review

Published on 28 Oct 2014

The inducible caspase-9 suicide gene system as a “safety switch” to limit on-target, off-tumor toxicities of chimeric antigen receptor T cells

in Experimental Pharmacology and Drug Discovery

Tessa Gargett
Michael P. Brown

Frontiers in Pharmacology

doi 10.3389/fphar.2014.00235

56,973 views
376 citations

Original Research

Published on 14 Sep 2022

Combinatorial suicide gene strategies for the safety of cell therapies

in T Cell Biology

Corey Falcon
Lauren Smith
Mustafa Al-Obaidi
Mohammed Abu Zaanona
Katelyn Purvis
Kentaro Minagawa
Mohammad Athar
Donna Salzman
Ravi Bhatia
Frederick Goldman

Frontiers in Immunology

doi 10.3389/fimmu.2022.975233

7,480 views
11 citations