Insulin Gene | List of Frontiers open access articles

Original Research

Published on 07 Nov 2023

The liver-derived exosomes stimulate insulin gene expression in pancreatic beta cells under condition of insulin resistance

in Diabetes: Molecular Mechanisms

Azam Mahmoudi-Aznaveh
Gholamreza Tavoosidana
Hossein Najmabadi
Zahra Azizi
Amin Ardestani

Frontiers in Endocrinology

doi 10.3389/fendo.2023.1303930

5,638 views
17 citations

Original Research

Published on 26 Mar 2024

Induction of islet autoimmunity to defective ribosomal product of the insulin gene as neoantigen after anti-cancer immunotherapy leading to autoimmune diabetes

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Rene van Tienhoven
Diahann T. S. L. Jansen
Miso Park
John C. Williams
James Larkin
Sergio A. Quezada
Bart O. Roep

Frontiers in Immunology

doi 10.3389/fimmu.2024.1384406

4,470 views
3 citations

Mini Review

Published on 03 Feb 2025

Vitamin D on the susceptibility of gestational diabetes mellitus: a mini-review

in Clinical Nutrition

Ting Zhang
Lan Yang
Shuman Yang
Song Gao

Frontiers in Nutrition

doi 10.3389/fnut.2025.1514148

5,410 views
4 citations

Case Report

Published on 28 Jul 2022

Case report: ISL2 is involved in malignant transformation in a patient with multiple relapsed oligodendroglioma

in Cancer Molecular Targets and Therapeutics

Shu-Na Chen
Zhongyong Wang
Di-Sheng Zhou
Xue-Qi Liu
Tao-Yi Mai
Zhao-Xia Dong
Miao Li
Xing-Ding Zhang
Lin Qi

Frontiers in Oncology

doi 10.3389/fonc.2022.969191

2,101 views

Mini Review

Published on 26 Apr 2021

The Role of Vascular Cells in Pancreatic Beta-Cell Function

in Diabetes: Molecular Mechanisms

Guzel Burganova
Claire Bridges
Peter Thorn
Limor Landsman

Frontiers in Endocrinology

doi 10.3389/fendo.2021.667170

12,000 views
56 citations

Brief Research Report

Published on 09 Feb 2021

Silencing of the tRNA Modification Enzyme Cdkal1 Effects Functional Insulin Synthesis in NIT-1 Cells: tRNALys3 Lacking ms2- (ms2t6A37) is Unable to Establish Sufficient Anticodon:Codon Interactions to Decode the Wobble Codon AAG

in Cellular Biochemistry

Amithi Narendran
Sweta Vangaveti
Srivathsan V. Ranganathan
Emily Eruysal
Miranda Craft
Omar Alrifai
Fu Yee Chua
Kathryn Sarachan
Breann Litwa
Sheetal Ramachandran

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2020.584228

5,083 views
5 citations

Original Research

Published on 14 Oct 2021

A Humanized Mouse Strain That Develops Spontaneously Immune-Mediated Diabetes

in Autoimmune and Autoinflammatory Disorders

Sandrine Luce
Sophie Guinoiseau
Alexis Gadault
Franck Letourneur
Patrick Nitschke
Marc Bras
Michel Vidaud
Pierre Charneau
Etienne Larger
Maikel L. Colli

Frontiers in Immunology

doi 10.3389/fimmu.2021.748679

6,522 views
12 citations

Review

Published on 27 Mar 2024

Revolutionizing pediatric neuroblastoma treatment: unraveling new molecular targets for precision interventions

in Cancer Cell Biology

Min Zheng
Ankush Kumar
Vishakha Sharma
Tapan Behl
Aayush Sehgal
Pranay Wal
Nirmala Vikram Shinde
Bhosale Sachin Kawaduji
Anupriya Kapoor
Md. Khalid Anwer

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2024.1353860

9,683 views
8 citations

Clinical Trial

Published on 26 Jul 2024

Chinese classical decoction Wuwei Xiaodu Drink alleviates gout arthritis by suppressing NLRP3-Mediated inflammation

in Ethnopharmacology

Na Lin
Qiaoding Dai
Yan Zhang
Liping Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1388753

4,921 views
7 citations

Original Research

Published on 23 Nov 2021

The Effect of Oxidized Fish Oil on the Spleen Index, Antioxidant Activity, Histology and Transcriptome in Juvenile Hybrid Grouper (♀ Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatus)

in Aquatic Physiology

Shuisheng Long
Zhihao Li
Xiaohui Dong
Xiaobo Yan
Hao Liu
Beiping Tan
Shuang Zhang
Simiao Pan
Tao Li
Xiangxiang Suo

Frontiers in Marine Science

doi 10.3389/fmars.2021.779305

5,736 views
5 citations

Review

Published on 30 Sep 2021

Structural Lessons From the Mutant Proinsulin Syndrome

in Molecular and Structural Endocrinology

Balamurugan Dhayalan
Deepak Chatterjee
Yen-Shan Chen
Michael A. Weiss

Frontiers in Endocrinology

doi 10.3389/fendo.2021.754693

6,916 views
15 citations

Mini Review

Published on 26 Nov 2018

The Prohormone Proinsulin as a Neuroprotective Factor: Past History and Future Prospects

in Molecular Signalling and Pathways

Flora de Pablo
Catalina Hernández-Sánchez
Enrique J. de la Rosa

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2018.00426

5,003 views
6 citations

Original Research

Published on 16 Mar 2023

EpiCRISPR targeted methylation of Arx gene initiates transient switch of mouse pancreatic alpha to insulin-producing cells

in Diabetes: Molecular Mechanisms

Marija Đorđević
Peter Stepper
Clarissa Feuerstein-Akgoz
Clarissa Gerhauser
Verica Paunović
Anja Tolić
Jovana Rajić
Svetlana Dinić
Aleksandra Uskoković
Nevena Grdović

Frontiers in Endocrinology

doi 10.3389/fendo.2023.1134478

7,682 views
16 citations

Original Research

Published on 13 Jan 2015

Cooperation between HMGA1, PDX-1, and MafA is Essential for Glucose-Induced Insulin Transcription in Pancreatic Beta Cells

in Systems Endocrinology

Biagio Arcidiacono
Stefania Iiritano
Eusebio Chiefari
Francesco S. Brunetti
Guoqiang Gu
Daniela Patrizia Foti
Antonio Brunetti

Frontiers in Endocrinology

doi 10.3389/fendo.2014.00237

10,417 views
47 citations

Review

Published on 05 Mar 2025

Exploring proinsulin proteostasis: insights into beta cell health and diabetes

in Cellular Biochemistry

Parisima Ghaffarian Zavarzadeh
Kathigna Panchal
Dylan Bishop
Elizabeth Gilbert
Mahi Trivedi
Tovaria Kee
Srivastav Ranganathan
Anoop Arunagiri

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1554717

6,241 views
6 citations

Original Research

Published on 07 Feb 2023

The isl2a transcription factor regulates pituitary development in zebrafish

in Thyroid Endocrinology

Chen-Yan Yan
Feng-Yao Wu
Feng Sun
Ya Fang
Rui-Jia Zhang
Chang-Run Zhang
Cao-Xu Zhang
Zheng Wang
Rui-Meng Yang
Liu Yang

Frontiers in Endocrinology

doi 10.3389/fendo.2023.920548

4,479 views
5 citations

Articles

The liver-derived exosomes stimulate insulin gene expression in pancreatic beta cells under condition of insulin resistance

Induction of islet autoimmunity to defective ribosomal product of the insulin gene as neoantigen after anti-cancer immunotherapy leading to autoimmune diabetes

Vitamin D on the susceptibility of gestational diabetes mellitus: a mini-review

Case report: ISL2 is involved in malignant transformation in a patient with multiple relapsed oligodendroglioma

The Role of Vascular Cells in Pancreatic Beta-Cell Function

Silencing of the tRNA Modification Enzyme Cdkal1 Effects Functional Insulin Synthesis in NIT-1 Cells: tRNALys3 Lacking ms2- (ms2t6A37) is Unable to Establish Sufficient Anticodon:Codon Interactions to Decode the Wobble Codon AAG

A Humanized Mouse Strain That Develops Spontaneously Immune-Mediated Diabetes

Revolutionizing pediatric neuroblastoma treatment: unraveling new molecular targets for precision interventions

Chinese classical decoction Wuwei Xiaodu Drink alleviates gout arthritis by suppressing NLRP3-Mediated inflammation

The Effect of Oxidized Fish Oil on the Spleen Index, Antioxidant Activity, Histology and Transcriptome in Juvenile Hybrid Grouper (♀ Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatus)

Structural Lessons From the Mutant Proinsulin Syndrome

The Prohormone Proinsulin as a Neuroprotective Factor: Past History and Future Prospects

EpiCRISPR targeted methylation of Arx gene initiates transient switch of mouse pancreatic alpha to insulin-producing cells

Cooperation between HMGA1, PDX-1, and MafA is Essential for Glucose-Induced Insulin Transcription in Pancreatic Beta Cells

Exploring proinsulin proteostasis: insights into beta cell health and diabetes

The isl2a transcription factor regulates pituitary development in zebrafish