Integrase In | List of Frontiers open access articles

Mini Review

Published on 13 Oct 2011

Non-Enzymatic Functions of Retroviral Integrase: The Next Target for Novel Anti-HIV Drug Development

in Virology

Takao Masuda

Frontiers in Microbiology

doi 10.3389/fmicb.2011.00210

10,719 views
15 citations

Original Research

Published on 10 Jun 2016

Development and Identification of a Novel Anti-HIV-1 Peptide Derived by Modification of the N-Terminal Domain of HIV-1 Integrase

in Virology

Marina Sala
Antonia Spensiero
Francesca Esposito
Maria C. Scala
Ermelinda Vernieri
Alessia Bertamino
Michele Manfra
Alfonso Carotenuto
Paolo Grieco
Ettore Novellino

Frontiers in Microbiology

doi 10.3389/fmicb.2016.00845

5,680 views
16 citations

Original Research

Published on 20 Mar 2017

Chelation Motifs Affecting Metal-dependent Viral Enzymes: N′-acylhydrazone Ligands as Dual Target Inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H Domain

in Virology

Mauro Carcelli
Dominga Rogolino
Anna Gatti
Nicolino Pala
Angela Corona
Alessia Caredda
Enzo Tramontano
Christophe Pannecouque
Lieve Naesens
Francesca Esposito

Frontiers in Microbiology

doi 10.3389/fmicb.2017.00440

5,636 views
31 citations

Original Research

Published on 02 Aug 2018

Structural Implications of Genotypic Variations in HIV-1 Integrase From Diverse Subtypes

in Virology

Leonard Rogers
Adetayo E. Obasa
Graeme B. Jacobs
Stefan G. Sarafianos
Anders Sönnerborg
Ujjwal Neogi
Kamalendra Singh

Frontiers in Microbiology

doi 10.3389/fmicb.2018.01754

6,360 views
24 citations

Original Research

Published on 19 Jun 2020

Quantum-Chemistry Based Design of Halobenzene Derivatives With Augmented Affinities for the HIV-1 Viral G4/C16 Base-Pair

in Theoretical and Computational Chemistry

Perla El Darazi
Léa El Khoury
Krystel El Hage
Richard G. Maroun
Zeina Hobaika
Jean-Philip Piquemal
Nohad Gresh

Frontiers in Chemistry

doi 10.3389/fchem.2020.00440

3,184 views
2 citations

Original Research

Published on 05 Nov 2025

Prevalence of primary HIV-1 drug resistance among antiretroviral-naïve individuals in Togo in 2023: a national study

in Infectious Diseases: Epidemiology and Prevention

Alassane Ouro-Medeli
Roméo M. Togan
Laetitia Serrano
Christelle Butel
Rogatien Atoun
Frederic Youa
Komlan Ali-Edje
Messanh Douffan
Phyllis Ehlan
Kokou Tegueni

Frontiers in Public Health

doi 10.3389/fpubh.2025.1605763

1,832 views
1 citation

Original Research

Published on 26 Mar 2025

High concordance of human immunodeficiency virus-1 genotypic drug resistance generated from paired cerebrospinal fluid and plasma in antiretroviral therapy -naive or -experienced patients

in Virology

Xizi Deng
Jiaojiao Li
Ruiying He
Yingfen Wen
Yaqing Lin
Liya Li
Xuemei Ling
Fengyu Hu
Linghua Li
Yun Lan

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1518225

1,874 views

Original Research

Published on 14 Jul 2022

Genetic Diversity and Low Therapeutic Impact of Variant-Specific Markers in HIV-1 Pol Proteins

in Virology

Paloma Troyano-Hernáez
Roberto Reinosa
Africa Holguín

Frontiers in Microbiology

doi 10.3389/fmicb.2022.866705

5,484 views
13 citations

Articles

Non-Enzymatic Functions of Retroviral Integrase: The Next Target for Novel Anti-HIV Drug Development

Development and Identification of a Novel Anti-HIV-1 Peptide Derived by Modification of the N-Terminal Domain of HIV-1 Integrase

Chelation Motifs Affecting Metal-dependent Viral Enzymes: N′-acylhydrazone Ligands as Dual Target Inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H Domain

Structural Implications of Genotypic Variations in HIV-1 Integrase From Diverse Subtypes

Quantum-Chemistry Based Design of Halobenzene Derivatives With Augmented Affinities for the HIV-1 Viral G4/C16 Base-Pair

Prevalence of primary HIV-1 drug resistance among antiretroviral-naïve individuals in Togo in 2023: a national study

High concordance of human immunodeficiency virus-1 genotypic drug resistance generated from paired cerebrospinal fluid and plasma in antiretroviral therapy -naive or -experienced patients

Genetic Diversity and Low Therapeutic Impact of Variant-Specific Markers in HIV-1 Pol Proteins