Intracellular Domain | List of Frontiers open access articles

Brief Research Report

Published on 23 Sep 2022

Sirtuin1 meditated modification of Notch1 intracellular domain regulates nucleolar localization and activation of distinct signaling cascades

in Cell Death and Survival

Neetu Saini
Geetha Bheeshmachar
Apurva Sarin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.988816

3,468 views
1 citation

Original Research

Published on 02 May 2023

Inhibition of the intracellular domain of Notch1 results in vascular endothelial cell dysfunction in sepsis

in Inflammation

Tingyan Liu
Caiyan Zhang
Jiayun Ying
Yaodong Wang
Gangfeng Yan
Yufeng Zhou
Guoping Lu

Frontiers in Immunology

doi 10.3389/fimmu.2023.1134556

6,398 views
15 citations

Original Research

Published on 03 Nov 2022

Teneurin paralogues are able to localise synaptic sites driven by the intracellular domain and have the potential to form cis-heterodimers

in Neurodevelopment

Angela Cheung
Greta Schachermayer
Aude Biehler
Amber Wallis
Mégane Missaire
Robert Hindges

Frontiers in Neuroscience

doi 10.3389/fnins.2022.915149

4,562 views
7 citations

Original Research

Published on 02 Apr 2024

Plexin B3 guides axons to cross the midline in vivo

in Cellular Neuropathology

Zhi-Zhi Liu
Ling-Yan Liu
Lou-Yin Zhu
Jian Zhu
Jia-Yu Luo
Ye-Fan Wang
Hong A. Xu

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2024.1292969

3,217 views

Original Research

Published on 18 Jan 2017

The Alzheimer's Disease-Associated R47H Variant of TREM2 Has an Altered Glycosylation Pattern and Protein Stability

in Neurodegeneration

Ji-Seon Park
In Jung Ji
Dong-Hou Kim
Hyun Joo An
Seung-Yong Yoon

Frontiers in Neuroscience

doi 10.3389/fnins.2016.00618

10,287 views
49 citations

Original Research

Published on 16 Jun 2016

Structural Studies of GABAA Receptor Binding Sites: Which Experimental Structure Tells us What?

in Molecular Signalling and Pathways

Roshan Puthenkalam
Marcel Hieckel
Xenia Simeone
Chonticha Suwattanasophon
Roman V. Feldbauer
Gerhard F. Ecker
Margot Ernst

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2016.00044

24,685 views
84 citations

Original Research

Published on 28 Sep 2021

Notch Intracellular Domain Plasmid Delivery via Poly(Lactic-Co-Glycolic Acid) Nanoparticles to Upregulate Notch Pathway Molecules

in Atherosclerosis and Vascular Medicine

Victoria L. Messerschmidt
Uday Chintapula
Aneetta E. Kuriakose
Samantha Laboy
Thuy Thi Dang Truong
LeNaiya A. Kydd
Justyn Jaworski
Zui Pan
Hesham Sadek
Kytai T. Nguyen

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.707897

4,587 views
6 citations

Review

Published on 23 Dec 2013

Neprilysin and Aβ Clearance: Impact of the APP Intracellular Domain in NEP Regulation and Implications in Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Marcus O Grimm
Janine Mett
Christoph Peter Stahlmann
Viola Jessica Haupenthal
Valerie Christin Zimmer
Tobias Hartmann

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2013.00098

27,738 views
147 citations

Correction

Published on 26 Oct 2021

Corrigendum: Notch Intracellular Domain Plasmid Delivery via Poly(Lactic-Co-Glycolic Acid) Nanoparticles to Upregulate Notch Pathway Molecules

in Atherosclerosis and Vascular Medicine

Victoria L. Messerschmidt
Uday Chintapula
Aneetta E. Kuriakose
Samantha Laboy
Thuy Thi Dang Truong
LeNaiya A. Kydd
Justyn Jaworski
Zui Pan
Hesham Sadek
Kytai T. Nguyen

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.785910

1,920 views

Original Research

Published on 19 May 2015

APP intracellular domain derived from amyloidogenic β- and γ-secretase cleavage regulates neprilysin expression

in Alzheimer's Disease and Related Dementias

Marcus Otto Grimm
Janine Mett
Christoph Peter Stahlmann
Sven Grösgen
Viola Jessica Haupenthal
Tamara Blümel
Benjamin Hundsdörfer
Valerie Christin Zimmer
Nadine Tamara Mylonas
Heikki Tanila

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2015.00077

11,691 views
66 citations

Original Research

Published on 07 Dec 2023

Altered synaptic plasticity at hippocampal CA1–CA3 synapses in Alzheimer's disease: integration of amyloid precursor protein intracellular domain and amyloid beta effects into computational models

Justinas J. Dainauskas
Paola Vitale
Sebastien Moreno
Hélène Marie
Michele Migliore
Ausra Saudargiene

Frontiers in Computational Neuroscience

doi 10.3389/fncom.2023.1305169

5,981 views
5 citations

Original Research

Published on 27 Mar 2023

Toward high-throughput engineering techniques for improving CAR intracellular signaling domains

in Cell and Gene Therapy

Savannah E. Butler
Colin J. Hartman
Yina H. Huang
Margaret E. Ackerman

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2023.1101122

4,913 views
6 citations

Brief Research Report

Published on 20 Feb 2025

Insights into the diversity and conservation of the chB6 alloantigen

in B Cell Biology

Phillip E. Funk

Frontiers in Immunology

doi 10.3389/fimmu.2025.1547896

1,618 views

Mini Review

Published on 07 Mar 2017

CD44: A Multifunctional Cell Surface Adhesion Receptor Is a Regulator of Progression and Metastasis of Cancer Cells

in Cell Adhesion and Migration

Linda T. Senbanjo
Meenakshi A. Chellaiah

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2017.00018

133,088 views
780 citations

Brief Research Report

Published on 29 Apr 2021

The Earliest T-Precursors in the Mouse Embryo Are Susceptible to Leukemic Transformation

in Stem Cell Research

Jixin Ding
Angelo A. Cardoso
Momoko Yoshimoto
Michihiro Kobayashi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.634151

3,628 views
5 citations

Mini Review

Published on 28 Jul 2023

Recent advances in in situ Notch signaling measurement

in Morphogenesis and Patterning

Masaharu Yoshihara
Satoru Takahashi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2023.1244105

4,040 views
4 citations

Articles

Sirtuin1 meditated modification of Notch1 intracellular domain regulates nucleolar localization and activation of distinct signaling cascades

Inhibition of the intracellular domain of Notch1 results in vascular endothelial cell dysfunction in sepsis

Teneurin paralogues are able to localise synaptic sites driven by the intracellular domain and have the potential to form cis-heterodimers

Plexin B3 guides axons to cross the midline in vivo

The Alzheimer's Disease-Associated R47H Variant of TREM2 Has an Altered Glycosylation Pattern and Protein Stability

Structural Studies of GABAA Receptor Binding Sites: Which Experimental Structure Tells us What?

Notch Intracellular Domain Plasmid Delivery via Poly(Lactic-Co-Glycolic Acid) Nanoparticles to Upregulate Notch Pathway Molecules

Neprilysin and Aβ Clearance: Impact of the APP Intracellular Domain in NEP Regulation and Implications in Alzheimer’s Disease

Corrigendum: Notch Intracellular Domain Plasmid Delivery via Poly(Lactic-Co-Glycolic Acid) Nanoparticles to Upregulate Notch Pathway Molecules

APP intracellular domain derived from amyloidogenic β- and γ-secretase cleavage regulates neprilysin expression

Altered synaptic plasticity at hippocampal CA1–CA3 synapses in Alzheimer's disease: integration of amyloid precursor protein intracellular domain and amyloid beta effects into computational models

Toward high-throughput engineering techniques for improving CAR intracellular signaling domains

Insights into the diversity and conservation of the chB6 alloantigen

CD44: A Multifunctional Cell Surface Adhesion Receptor Is a Regulator of Progression and Metastasis of Cancer Cells

The Earliest T-Precursors in the Mouse Embryo Are Susceptible to Leukemic Transformation

Recent advances in in situ Notch signaling measurement