Intractable Problems | List of Frontiers open access articles

Original Research

Published on 02 Mar 2026

Genetic diversity and population structure of Omani date palm assessed by SSR markers

in Plant Genetics, Epigenetics and Chromosome Biology

Al-Ghaliya Humaid Al-Mamari
Abdullah Hamed Al-Jabri
Sean Mayes

Frontiers in Plant Science

doi 10.3389/fpls.2026.1776708

Editorial

Published on 02 Mar 2026

Editorial: Clinical imaging, neurophysiological, neuropathology and neuroethics studies on disorders of consciousness, coma mechanisms, and theories of consciousness: a unifying attempt

in Neurocritical and Neurohospitalist Care

Diego Iacono
Manuel Trachsel
Thanh G. Phan
Charlène Aubinet

Frontiers in Neurology

doi 10.3389/fneur.2026.1803326

122 views

Systematic Review

Published on 02 Mar 2026

Synthetic relationships with Social Pedagogical Agents in education: a scoping literature review

in AI for Human Learning and Behavior Change

Sebas Nouwen
Janienke Sturm
Uwe Matzat
Wijnand IJsselsteijn

Frontiers in Artificial Intelligence

doi 10.3389/frai.2026.1625438

Original Research

Published on 02 Mar 2026

Genome-wide and co-expression network dissection of PgUGT-Rd1 as a central regulator of ginsenoside Rd biosynthesis in ginseng

in Plant Metabolism and Chemodiversity

Sizhang Liu
Meili Chi
Yi Wang
Meiping Zhang

Frontiers in Plant Science

doi 10.3389/fpls.2026.1751774

172 views

Original Research

Published on 02 Mar 2026

Collaborative scheduling of external container trucks and yard cranes for resilient port operations

in Marine Affairs and Policy

Yamin Zhou
Yongsheng Yang
Han Zhang
Bing Sun
Shiwen Zhu
Xinqiang Chen
Octavian Postolache

Frontiers in Marine Science

doi 10.3389/fmars.2026.1753197

108 views

Original Research

Published on 02 Mar 2026

Network toxicology and single-cell analysis reveal key gene-mediated bisphenol a interference with granulosa cell function in polycystic ovary syndrome

in Obstetric and Pediatric Pharmacology

Yan Zhang
Yuan Lin
Xiumei Xiong
Xiujuan Chen
Xiaoqing Liu
Hailong Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1754568

154 views

Review

Published on 02 Mar 2026

Photobiomodulation for the treatment of knee osteoarthritis: therapeutic effects and molecular mechanism

in Molecular and Cellular Pathology

Peng Xia
Tianxiang Fan
Yangxi Huang
Hanwen Zheng
Ruoxi Ma
Wenjin Zhou
Zhi Yao
Deli Wang
Guoqing Cui
Marco Pang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1744761

272 views

Original Research

Published on 02 Mar 2026

Inter-species feedbacks drive emergent productivity in agroforestry systems - an agent-based analysis

in Agroecological Cropping Systems

Luis R. Comolli
Hugo Fassola

Frontiers in Agronomy

doi 10.3389/fagro.2026.1657465

182 views

Original Research

Published on 02 Mar 2026

Age- and sex-dependent alterations of jejunal microbiota in Fischer 344 rats fed with a high-fructose, high-fat diet: depletion of Lactobacillus intestinalis in small bowel contents

in Microorganisms in Vertebrate Digestive Systems

Sungchan Ha
Nayoung Kim
Chin-Hee Song

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1779112

Review

Published on 02 Mar 2026

Personalizing ecological momentary intervention for substance use disorders through data-driven decision rules

in Addictive Disorders

Mina Kwon
Joo Yun Song
Jae Yeon Hwang
Su Jeong Seong
Kee Jeong Park
Young Tak Jo
Yeo Jin Kim
Moo Eob Ahn
Sang-Kyu Lee

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1717544

185 views

Original Research

Published on 02 Mar 2026

Relevance and limitations of clinical follow-up in a pharmacokinetic study on direct oral anticoagulants

in Cardiovascular and Smooth Muscle Pharmacology

Jean Terrier
Pauline Gosselin
Christophe Combescure
Pierre Fontana
Youssef Daali
Jean-Luc Reny
Chantal Alves
Frederic Gaspar
Monia Guidi
Lenoir Camille

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1761151

133 views

Original Research

Published on 02 Mar 2026

Celastrol increases anoikis sensitivity to suppress triple-negative breast cancer via EGFR pathway and p-EMT state regulation

in Pharmacology of Anti-Cancer Drugs

Jue Yang
Xiangpeng Wang
Xiuyun Bai
Rongjun Deng
Wanting Ye
Qiqiong Liu
Ying Xing
Yuxing Yao
Aiping Lyu
Cheng Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1747871

Original Research

Published on 02 Mar 2026

A multilevel model of university quality in Peru: an integrated evaluation of student satisfaction, competency development, and employment outcomes

in Higher Education

Walter Stalin Gil Quevedo
Abraham William Garcia Chapoñan
Moises Luis Cornelio Vicuña
Miguen Hernan Yengle Ruiz

Frontiers in Education

doi 10.3389/feduc.2026.1759422

166 views

Original Research

Accepted on 28 Feb 2026

Perceptions, Attitudes, and Curriculum Reflections: Exploring Healthcare Students' Engagement with Basic Medical Sciences in Saudi Arabia

in Healthcare Professions Education

Khalid Al-Hamad
Abdullah Aljuhani
Turki Almutairi
Hanan Shanab
Reem Almutairi
Angel Mary
Saraswathi Ilango
Saikarthik Jayakumar

Frontiers in Medicine

Review

Accepted on 28 Feb 2026

The Sarcopenia–Pain Connection: Why Mechanisms Matter for Patient Care?

in Musculoskeletal Pain

Giovanni Iolascon
Antimo Moretti

Frontiers in Pain Research

Original Research

Accepted on 28 Feb 2026

Development of Peribronchiolar Fibrosis Is Associated with Local Immune and MAPK Pathway Activation in a Murine Model of Deployment-Related Constrictive Bronchiolitis

in Environmental Health and Exposome

Seagal Teitz-Tennenbaum
Kayla M Marinetti
Anutosh Ganguly
Brian Song
Helen Hicks
John J Osterholzer

Frontiers in Public Health

Articles

Genetic diversity and population structure of Omani date palm assessed by SSR markers

Editorial: Clinical imaging, neurophysiological, neuropathology and neuroethics studies on disorders of consciousness, coma mechanisms, and theories of consciousness: a unifying attempt

Synthetic relationships with Social Pedagogical Agents in education: a scoping literature review

Genome-wide and co-expression network dissection of PgUGT-Rd1 as a central regulator of ginsenoside Rd biosynthesis in ginseng

Collaborative scheduling of external container trucks and yard cranes for resilient port operations

Network toxicology and single-cell analysis reveal key gene-mediated bisphenol a interference with granulosa cell function in polycystic ovary syndrome

Photobiomodulation for the treatment of knee osteoarthritis: therapeutic effects and molecular mechanism

Inter-species feedbacks drive emergent productivity in agroforestry systems - an agent-based analysis

Age- and sex-dependent alterations of jejunal microbiota in Fischer 344 rats fed with a high-fructose, high-fat diet: depletion of Lactobacillus intestinalis in small bowel contents

Personalizing ecological momentary intervention for substance use disorders through data-driven decision rules

Relevance and limitations of clinical follow-up in a pharmacokinetic study on direct oral anticoagulants

Celastrol increases anoikis sensitivity to suppress triple-negative breast cancer via EGFR pathway and p-EMT state regulation

A multilevel model of university quality in Peru: an integrated evaluation of student satisfaction, competency development, and employment outcomes

Perceptions, Attitudes, and Curriculum Reflections: Exploring Healthcare Students' Engagement with Basic Medical Sciences in Saudi Arabia

The Sarcopenia–Pain Connection: Why Mechanisms Matter for Patient Care?

Development of Peribronchiolar Fibrosis Is Associated with Local Immune and MAPK Pathway Activation in a Murine Model of Deployment-Related Constrictive Bronchiolitis