Intractable Problems | List of Frontiers open access articles

Review

Published on 02 Mar 2026

Oleanolic acid and its derivatives in breast cancer therapy: mechanistic insights, structural modifications, and novel delivery strategies

in Pharmacology of Anti-Cancer Drugs

Xiaofei Hu
Yuting Qin

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1755987

158 views

Systematic Review

Published on 02 Mar 2026

Risk factors for acute kidney injury following transcatheter aortic valve replacement: a systematic review and meta-analysis

in Heart Valve Disease

Nan Jiang
Xue Liu
Jiwei Huang
Yi Jiang
Dan Li

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1684953

100 views

Original Research

Published on 02 Mar 2026

Invasive stratified mucin-producing carcinoma of the cervix: a report of 34 cases of immunohistochemical and clinicopathological findings

in Gynecological Oncology

Ru Wang
Linlin Zhang
Di Zhao
Ming Liu
Ting Hao
Songsheng Zhang
Lianbao Cao
Hao Yu

Frontiers in Oncology

doi 10.3389/fonc.2026.1681399

Original Research

Published on 02 Mar 2026

Advances in biodigital systems: combining TPMS with varying porosity and moss for future eco-intelligent environments

in Sustainable Design and Construction

Enza Migliore
Ran Che
Jingze Liu

Frontiers in Built Environment

doi 10.3389/fbuil.2026.1688558

136 views

Original Research

Published on 02 Mar 2026

A real-world 10-year follow-up analysis of survival and safety of CD20-targeted therapy in patients with Waldenstrom macroglobulinemia

in Hematologic Malignancies

Hengming Zhang
Xufei Huang
Yirong Zhu
Zhihong Zheng
Rong Zhan
Shaoyuan Wang

Frontiers in Oncology

doi 10.3389/fonc.2026.1733209

178 views

Original Research

Published on 02 Mar 2026

Patient-derived cell lines unveil COL1A2 as a predictor of docetaxel resistance in breast cancer

in Breast Cancer

Yuwei Gao
Rong Wang
Xiaowei Dou
Song Chen
Wenhao Chen
Jinting Liu
Suo Zhu
Jianjun Huang
Qingjun Gao

Frontiers in Oncology

doi 10.3389/fonc.2025.1737405

310 views

Original Research

Published on 02 Mar 2026

Cultural congruence and educational equity: how ethnic minority teachers promote minority students’ school adaptation and its underlying psychological mechanisms

in Cultural Psychology

Zipei Ouyang
Liang Jing
Cheng Li
Jiaohui Tang

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1739625

Original Research

Published on 02 Mar 2026

Single-cell transcriptomics reveals heterogeneous neutrophil populations and diagnostic biomarkers in atherosclerosis

in Vascular Physiology

Ping Wang
Qiang Fu
Yuefeng Cai
Jiaxin Yang
Zhenzhen Cui
Qiyu Sun
Quanli Qiu
Xiaowen Ma
Min Li

Frontiers in Physiology

doi 10.3389/fphys.2026.1704443

326 views

Original Research

Published on 02 Mar 2026

Impact of occupational pairing on women’s fertility plans: roles of domestic burden and housework satisfaction

in Sociology of Families

Yuan Dang

Frontiers in Sociology

doi 10.3389/fsoc.2026.1617449

193 views

Original Research

Published on 02 Mar 2026

The protease inhibitor gabexate mesylate targets Raf kinase inhibitor protein and reverses epithelial–mesenchymal transition in triple-negative breast cancer cells

in Breast Cancer

Marzia Deserti
Simone Sabbioni
Francesca Poli
Francesco Vasuri
Valeria Relli
Andrea Palloni
Chiara Deiana
Giovanni Brandi
Simona Tavolari

Frontiers in Oncology

doi 10.3389/fonc.2026.1713273

215 views

Original Research

Published on 02 Mar 2026

Macrophage-derived CCL20 promotes abdominal aortic aneurysm progression via lymphocytes CCR6

in Inflammation

Qingnan Ren
Tianyong Sun
Song Shen
Yuanbin Cao
Li Wei
Yang Zhao
Fengxin Wan
Ping Sui
Ke Xiao
Hao Bai

Frontiers in Immunology

doi 10.3389/fimmu.2026.1780720

Methods

Published on 02 Mar 2026

A missed opportunity: how signal detection theory can advance research on prejudice detection

in Organizational Justice, Diversity, Equity, Inclusion, and Belonging

Stephanie M. Merritt

Frontiers in Organizational Psychology

doi 10.3389/forgp.2026.1629459

164 views

Original Research

Published on 02 Mar 2026

Metabolic dysfunction-associated steatotic liver disease and bone mineral density in type 2 diabetes mellitus: insights from a single-center cross-sectional study in North India

in Bone Research

Dogga Sudhakar
Sumit Rajotiya
Sourav Debnath
Nishant Jain
Monal Sherekar
Shivang Mishra
Anurag Kumar Singh
Mahaveer Singh
Avinash Munshi
Deepak Nathiya

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1758966

Original Research

Published on 02 Mar 2026

Multimodal imaging features of non-proliferative and proliferative diabetic retinopathy based on SD-OCT and fundus autofluorescence

in Ophthalmology

Zixun Wang
Chenxi Ji
Xiaoxue Hu
Tingyu Zhang
Tingxi Liu
Xiaoling Zhang
Yuhang Wang
Zhiqing Li
Xiuhong Qin
Ming Sun

Frontiers in Medicine

doi 10.3389/fmed.2026.1779259

175 views

Policy Brief

Published on 02 Mar 2026

Restoring a sense of safety among survivors of sexual harassment in higher education: policy recommendations from the UNI4EQUITY multinational study

in Gender, Sex and Sexualities

Sylwia Jaskulska
Barbara Jankowiak
Vanesa Perez-Martrnez
Stefano Porru
Angela Carta
Marlies Wallner
Viktoria Stifter
Joana Topa
Iwetta Andruszkiewicz
Katarzyna Waszyńska

Frontiers in Sociology

doi 10.3389/fsoc.2026.1782978

Original Research

Published on 02 Mar 2026

Uric acid and hyperuricemia in relation to non-alcoholic fatty liver disease among individuals with type 2 diabetes: insights from a cross-sectional analysis

in Clinical Diabetes

Chunbo Li
Mengfan Zhang
Mengchun Li
Qifeng Shao

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1720601

Articles

Oleanolic acid and its derivatives in breast cancer therapy: mechanistic insights, structural modifications, and novel delivery strategies

Risk factors for acute kidney injury following transcatheter aortic valve replacement: a systematic review and meta-analysis

Invasive stratified mucin-producing carcinoma of the cervix: a report of 34 cases of immunohistochemical and clinicopathological findings

Advances in biodigital systems: combining TPMS with varying porosity and moss for future eco-intelligent environments

A real-world 10-year follow-up analysis of survival and safety of CD20-targeted therapy in patients with Waldenstrom macroglobulinemia

Patient-derived cell lines unveil COL1A2 as a predictor of docetaxel resistance in breast cancer

Cultural congruence and educational equity: how ethnic minority teachers promote minority students’ school adaptation and its underlying psychological mechanisms

Single-cell transcriptomics reveals heterogeneous neutrophil populations and diagnostic biomarkers in atherosclerosis

Impact of occupational pairing on women’s fertility plans: roles of domestic burden and housework satisfaction

The protease inhibitor gabexate mesylate targets Raf kinase inhibitor protein and reverses epithelial–mesenchymal transition in triple-negative breast cancer cells

Macrophage-derived CCL20 promotes abdominal aortic aneurysm progression via lymphocytes CCR6

A missed opportunity: how signal detection theory can advance research on prejudice detection

Metabolic dysfunction-associated steatotic liver disease and bone mineral density in type 2 diabetes mellitus: insights from a single-center cross-sectional study in North India

Multimodal imaging features of non-proliferative and proliferative diabetic retinopathy based on SD-OCT and fundus autofluorescence

Restoring a sense of safety among survivors of sexual harassment in higher education: policy recommendations from the UNI4EQUITY multinational study

Uric acid and hyperuricemia in relation to non-alcoholic fatty liver disease among individuals with type 2 diabetes: insights from a cross-sectional analysis