Isotretinoin | List of Frontiers open access articles

Perspective

Published on 12 Nov 2021

Advantages of Tailored Isotretinoin Treatment in Moderate to Severe Acne: Real-Life Data

in Translational Pharmacology

Nevena Skroza
Ersilia Tolino
Veronica Balduzzi
Nicoletta Bernardini
Alessandra Mambrin
Anna Marchesiello
Federica Marraffa
Giovanni Rossi
Salvatore Volpe
Ilaria Proietti

Frontiers in Pharmacology

doi 10.3389/fphar.2021.733526

9,027 views
10 citations

Original Research

Published on 31 Aug 2022

Nontargeted metabolomics to characterize the effects of isotretinoin on skin metabolism in rabbit with acne

in Drug Metabolism and Transport

Xiao-Liang Ou-Yang
Deng Zhang
Xiu-Ping Wang
Si-Min Yu
Zhen Xiao
Wei Li
Chun-Ming Li

Frontiers in Pharmacology

doi 10.3389/fphar.2022.963472

5,444 views
12 citations

Original Research

Published on 08 Aug 2025

Integrated plasma metabolomic and proteomic analysis uncover the effects and mechanisms of isotretinoin in severe acne

in Drug Metabolism and Transport

Manqi Xia
Jing Zhang
Yang Hu
Ziyan Chen
Yanan Ke
Shujuan Zhang
Zeen Yang
Xin Tian
Jingyao Liang
Yumei Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1590820

3,062 views

Clinical Trial

Published on 09 Jan 2024

Lactobacillus plantarum MH-301 as an effective adjuvant to isotretinoin in the treatment of acne vulgaris: a randomized and open-label trail

in Dermatology

Lili Liang
Xinyue Qi
Xiaoke Jiang
Tingtao Chen
Lina Dong

Frontiers in Medicine

doi 10.3389/fmed.2023.1340068

10,059 views
10 citations

Original Research

Published on 25 Jul 2017

Non-antibiotic Isotretinoin Treatment Differentially Controls Propionibacterium acnes on Skin of Acne Patients

in Antimicrobials, Resistance and Chemotherapy

Angela E. Ryan-Kewley
David R. Williams
Neill Hepburn
Ronald A. Dixon

Frontiers in Microbiology

doi 10.3389/fmicb.2017.01381

15,322 views
24 citations

Case Report

Published on 28 Mar 2023

Perifolliculitis capitis abscedens et suffodiens treatment with tumor necrosis factor inhibitors and baricitinib: A case report and literature review

in Dermatology

Yuanting Yu
Xiaojie Ding
Fei Guo
Kan Ze
Xiaoying Sun
Xin Li

Frontiers in Medicine

doi 10.3389/fmed.2023.1132574

6,888 views
8 citations

Original Research

Published on 22 Jul 2022

Oral isotretinoin for acne vulgaris side effects on the ocular surface: Hyaluronic acid and galacto-xyloglucan as treatment for dry eye disease signs and symptoms

in Ophthalmology

María Carmen Sánchez-González
Concepción De-Hita-Cantalejo
Concepción Martínez-Lara
José-María Sánchez-González

Frontiers in Medicine

doi 10.3389/fmed.2022.959165

8,707 views
4 citations

Original Research

Published on 13 Jan 2026

Dual-filter IPL vs. LED phototherapy combined with systemic therapy for moderate-to-severe acne in Asian patients

in Dermatology

Xuetong Zhang
Wenjun Cui
Min Chen
Min Li

Frontiers in Medicine

doi 10.3389/fmed.2025.1742480

879 views

Systematic Review

Accepted on 23 Feb 2026

Individualizing isotretinoin dosing in acne: comparable 24-week efficacy and better tolerability at lower daily doses

in Dermatology

Zou Jingmin
Li Yuxing
Wang Lu
Jiang Ying
Fang Fumin
Shao Kai
Zhang Xiaoping
Zhu Tingting
Yu Xiuqin

Frontiers in Medicine

Clinical Trial

Published on 18 Jun 2018

A Comprehensive Safety Trial of Chimeric Antibody 14.18 With GM-CSF, IL-2, and Isotretinoin in High-Risk Neuroblastoma Patients Following Myeloablative Therapy: Children’s Oncology Group Study ANBL0931

in Cancer Immunity and Immunotherapy

M. Fevzi Ozkaynak
Andrew L. Gilman
Wendy B. London
Arlene Naranjo
Mitchell B. Diccianni
Sheena C. Tenney
Malcolm Smith
Karen S. Messer
Robert Seeger
C. Patrick Reynolds

Frontiers in Immunology

doi 10.3389/fimmu.2018.01355

13,793 views
85 citations

Original Research

Published on 01 Oct 2025

Mining and analysis of adverse event signals of isotretinoin based on the real-world data of FAERS database

in Dermatology

Liu Yang
Hanzhang Xie
Ying Jia
Bingnan Cui
Zhanshuo Xiao

Frontiers in Medicine

doi 10.3389/fmed.2025.1559972

3,096 views
2 citations

Original Research

Accepted on 28 Feb 2026

An Integrative Pharmacovigilance, Network Toxicology and Molecular Docking Study on Drug-Induced Cheilitis

in Pharmacoepidemiology

Xuefeng Wang
Shangzhi Han
Yingxue Huang
Lei Zhang
Xue Li
Liqin Yang
Yanbo Zhang

Frontiers in Pharmacology

Original Research

Published on 09 Feb 2026

Efficacy and safety of dinutuximab beta combined with GM-CSF and isotretinoin ± chemotherapy as first-line maintenance treatment for pediatric high-risk neuroblastoma in China

in Pediatric Oncology

Wen Zhao
Peiyi Yang
Jing Qin
Cheng Huang
Hongjun Fan
Mei Jin
Chao Duan
Ying Wu
Xisi Wang
Chunying Cui

Frontiers in Oncology

doi 10.3389/fonc.2026.1765578

670 views

Original Research

Published on 12 Jan 2026

The efficacy of red and blue light-emitting diode phototherapy combined with oral minocycline for acne conglobata: a retrospective cohort study

in Dermatology

Yonghong Hao
Xiaofang Zou
Yixuan Gao
Liyuan Xing
Chengxin Li

Frontiers in Medicine

doi 10.3389/fmed.2025.1708077

1,312 views

Original Research

Published on 12 Jun 2017

HLA-Bw4-I-80 Isoform Differentially Influences Clinical Outcome As Compared to HLA-Bw4-T-80 and HLA-A-Bw4 Isoforms in Rituximab or Dinutuximab-Based Cancer Immunotherapy

in Alloimmunity and Transplantation

Amy K. Erbe
Wei Wang
Patrick K. Reville
Lakeesha Carmichael
KyungMann Kim
Eneida A. Mendonca
Yiqiang Song
Jacquelyn A. Hank
Wendy B. London
Arlene Naranjo

Frontiers in Immunology

doi 10.3389/fimmu.2017.00675

7,996 views
21 citations

Original Research

Published on 22 Sep 2023

In vivo imaging of patients with chronic pruritus of unknown origin reveals partial sweat duct obstruction with partial itch resolution upon retinoid treatment

in Dermatology

Shi Yu Derek Lim
Yingrou Tan
Yuning Zhang
Xiahong Zhao
Lai Guan Ng
Hong Liang Tey

Frontiers in Medicine

doi 10.3389/fmed.2023.1265148

3,639 views
4 citations

Articles

Advantages of Tailored Isotretinoin Treatment in Moderate to Severe Acne: Real-Life Data

Nontargeted metabolomics to characterize the effects of isotretinoin on skin metabolism in rabbit with acne

Integrated plasma metabolomic and proteomic analysis uncover the effects and mechanisms of isotretinoin in severe acne

Lactobacillus plantarum MH-301 as an effective adjuvant to isotretinoin in the treatment of acne vulgaris: a randomized and open-label trail

Non-antibiotic Isotretinoin Treatment Differentially Controls Propionibacterium acnes on Skin of Acne Patients

Perifolliculitis capitis abscedens et suffodiens treatment with tumor necrosis factor inhibitors and baricitinib: A case report and literature review

Oral isotretinoin for acne vulgaris side effects on the ocular surface: Hyaluronic acid and galacto-xyloglucan as treatment for dry eye disease signs and symptoms

Dual-filter IPL vs. LED phototherapy combined with systemic therapy for moderate-to-severe acne in Asian patients

Individualizing isotretinoin dosing in acne: comparable 24-week efficacy and better tolerability at lower daily doses

A Comprehensive Safety Trial of Chimeric Antibody 14.18 With GM-CSF, IL-2, and Isotretinoin in High-Risk Neuroblastoma Patients Following Myeloablative Therapy: Children’s Oncology Group Study ANBL0931

Mining and analysis of adverse event signals of isotretinoin based on the real-world data of FAERS database

An Integrative Pharmacovigilance, Network Toxicology and Molecular Docking Study on Drug-Induced Cheilitis

Efficacy and safety of dinutuximab beta combined with GM-CSF and isotretinoin ± chemotherapy as first-line maintenance treatment for pediatric high-risk neuroblastoma in China

The efficacy of red and blue light-emitting diode phototherapy combined with oral minocycline for acne conglobata: a retrospective cohort study

HLA-Bw4-I-80 Isoform Differentially Influences Clinical Outcome As Compared to HLA-Bw4-T-80 and HLA-A-Bw4 Isoforms in Rituximab or Dinutuximab-Based Cancer Immunotherapy

In vivo imaging of patients with chronic pruritus of unknown origin reveals partial sweat duct obstruction with partial itch resolution upon retinoid treatment