Mini Review
Published on 08 Dec 2022
Molecular dissection of Janus kinases as drug targets for inflammatory diseases
in Molecular Innate Immunity
Frontiers in Immunology
doi 10.3389/fimmu.2022.1075192
- 5,513 views
- 22 citations
23 articles related to "Jaks"
Articles
Mini Review
Published on 26 Jan 2026
Revisiting Janus kinases as molecular drug targets for rheumatic diseases
in Rheumatology
Frontiers in Medicine
doi 10.3389/fmed.2026.1716179
- 749 views
Review
Published on 18 Apr 2017
The Janus Kinase (JAK) FERM and SH2 Domains: Bringing Specificity to JAK–Receptor Interactions
in Molecular and Structural Endocrinology
Frontiers in Endocrinology
doi 10.3389/fendo.2017.00071
- 22,077 views
- 123 citations
Original Research
Published on 06 Jun 2022
Inhibitors Targeting Multiple Janus Kinases From Zanthoxylum simulans Mediate Inhibition and Apoptosis Against Gastric Cancer Cells via the Estrogen Pathway
in Medicinal and Pharmaceutical Chemistry
Frontiers in Chemistry
doi 10.3389/fchem.2022.922110
- 3,981 views
- 11 citations
Review
Published on 25 Jul 2013
IFN Signaling: How a Non-Canonical Model Led to the Development of IFN Mimetics
in Vaccines and Molecular Therapeutics
Frontiers in Immunology
doi 10.3389/fimmu.2013.00202
- 10,221 views
- 21 citations
Original Research
Published on 29 Oct 2021
Ruxolitinib Ameliorates Airway Hyperresponsiveness and Lung Inflammation in a Corticosteroid-Resistant Murine Model of Severe Asthma
in Inflammation
Frontiers in Immunology
doi 10.3389/fimmu.2021.786238
- 5,433 views
- 18 citations
Review
Published on 13 Jul 2021
The Many Faces of JAKs and STATs Within the COVID-19 Storm
in Inflammation
Frontiers in Immunology
doi 10.3389/fimmu.2021.690477
- 9,870 views
- 24 citations
Mini Review
Published on 05 Jan 2018
Mechanistic Insights into Regulation of JAK2 Tyrosine Kinase
in Molecular and Structural Endocrinology
Frontiers in Endocrinology
doi 10.3389/fendo.2017.00361
- 26,354 views
- 90 citations
Review
Published on 21 Jun 2024
SOCS1 and SOCS3 as key checkpoint molecules in the immune responses associated to skin inflammation and malignant transformation
in Cytokines and Soluble Mediators in Immunity
Frontiers in Immunology
doi 10.3389/fimmu.2024.1393799
- 9,062 views
- 25 citations
Mini Review
Published on 08 Feb 2017
Dysregulation of SOCS-Mediated Negative Feedback of Cytokine Signaling in Carcinogenesis and Its Significance in Cancer Treatment
in Cancer Immunity and Immunotherapy
Frontiers in Immunology
doi 10.3389/fimmu.2017.00070
- 12,425 views
- 100 citations
Review
Published on 20 Nov 2017
Cytokines in Male Fertility and Reproductive Pathologies: Immunoregulation and Beyond
in Molecular and Structural Endocrinology
Frontiers in Endocrinology
doi 10.3389/fendo.2017.00307
- 25,036 views
- 194 citations
Review
Published on 26 Jan 2017
Canonical and Non-Canonical Aspects of JAK–STAT Signaling: Lessons from Interferons for Cytokine Responses
in Molecular Innate Immunity
Frontiers in Immunology
doi 10.3389/fimmu.2017.00029
- 47,179 views
- 306 citations
Review
Published on 29 Jun 2023
Janus kinase inhibitors in systemic lupus erythematosus: implications for tyrosine kinase 2 inhibition
in Rheumatology
Frontiers in Medicine
doi 10.3389/fmed.2023.1217147
- 14,986 views
- 29 citations
Review
Published on 24 Mar 2022
JAK/STAT Signaling: Molecular Targets, Therapeutic Opportunities, and Limitations of Targeted Inhibitions in Solid Malignancies
in Pharmacology of Anti-Cancer Drugs
Frontiers in Pharmacology
doi 10.3389/fphar.2022.821344
- 22,414 views
- 152 citations
Original Research
Published on 29 Jun 2022
The Non-Receptor Protein Tyrosine Phosphatase PTPN6 Mediates a Positive Regulatory Approach From the Interferon Regulatory Factor to the JAK/STAT Pathway in Litopenaeus vannamei
in Molecular Innate Immunity
Frontiers in Immunology
doi 10.3389/fimmu.2022.913955
- 5,391 views
- 18 citations
Original Research
Published on 12 Aug 2024
The JAK1/JAK2 inhibitor ruxolitinib inhibits mediator release from human basophils and mast cells
in Cytokines and Soluble Mediators in Immunity
Frontiers in Immunology
doi 10.3389/fimmu.2024.1443704
- 7,125 views
- 15 citations