Lead Discovery | List of Frontiers open access articles

Original Research

Published on 12 Feb 2026

A refined SMOTE-ENN optimization method based on machine learning for heart rate variability data classification

in Health Informatics

Biao Zhang
Muzi Liang
Yuanlun Zhou
Binbin Ji
Meng Han
Hongyan Li
Xufeng Lang
Yihua Song
Run Gao
Zuojian Zhou

Frontiers in Digital Health

doi 10.3389/fdgth.2026.1749570

198 views

Original Research

Published on 12 Feb 2026

Comparative mediator analysis: establishing links between mathematical thinking and creativity through digital game addiction and violent tendencies across gifted and non-gifted student groups

in Educational Psychology

Zübeyde Er
Ayça Akin
Hayriye Seda Sezgin

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1776528

207 views

Original Research

Published on 12 Feb 2026

Potential key factors? Exploring the predictive role and necessity of emotional intelligence and resilience for pre-service teachers’ critical thinking disposition

in Teacher Education

Yangyintao Zhao
Liangrui Ai

Frontiers in Education

doi 10.3389/feduc.2026.1729435

507 views

Original Research

Published on 12 Feb 2026

Prediction of treatment responsiveness to home-based transcranial photobiomodulation (tPBM) intervention for cognitive decline using fNIRS concurrently recorded during tPBM

in Alzheimer's Disease and Related Dementias

Minyoung Chun
Kyeonggu Lee
Bori Jung
Yunsu Kim
Chaeyeon Yang
JongKwan Choi
Jihyun Cha
Seung-Hwan Lee
Chang-Hwan Im

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2026.1716502

278 views

Original Research

Published on 12 Feb 2026

Resveratrol reduces muscle atrophy and stress pathway activation in a combined disuse-hypoxia-mouse model

in Experimental Pharmacology and Drug Discovery

Aziz Ahmad Khan
Sajid Khan Sadozai
Fawad Ali
Nemat Khan
Rizwan Qaisar

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1753486

229 views

Systematic Review

Published on 12 Feb 2026

Moral decision-making in patients with neurodegenerative diseases: a systematic review

in Cognition

Giorgia Capitani
Daniele Lozzi
Giuseppe Curcio
Simone Migliore

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1745923

347 views

Study Protocol

Published on 12 Feb 2026

Retraining and control therapy: sense of control and catastrophic symptom expectations as targets of a cognitive behavioral treatment for pediatric functional seizures

in Psychological Therapy and Psychosomatics

Caroline Watson
Badhma Valaiyapathi
Jerzy P. Szaflarski
Burel R. Goodin
Aaron D. Fobian

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1610446

230 views

Review

Published on 12 Feb 2026

mRNA vaccines transform personalized lung cancer treatment

in Vaccines and Molecular Therapeutics

Kaiqi Wei
Zitong Wan
Miaomiao Wen
Shaowei Xin
Yinxi Zhou
Jun Wei
Jianfei Zhu
Chengbin Tang
Yanlu Xiong
Tao Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1707654

1,110 views

Original Research

Published on 12 Feb 2026

A Treat-to-Target approach in hereditary angioedema: expert consensus from a European committee

in Molecular Innate Immunity

Mauro Cancian
Teresa Caballero
Isabelle Boccon-Gibod
Thomas Buttgereit
Danny Cohn
Efrem Eren
Sorena Kiani-Alikhan
David Launay
Johanna Mandelin
Andrea Zanichelli

Frontiers in Immunology

doi 10.3389/fimmu.2026.1773279

407 views

Original Research

Published on 12 Feb 2026

Training requirements and associated factors for nursing assistants in Jiaxing City, China: a cross-sectional study in healthcare settings

in Healthcare Professions Education

Feng-Yan Pu
Li-Ping Yu
Hui-Ping Shan

Frontiers in Medicine

doi 10.3389/fmed.2026.1710478

121 views

Original Research

Published on 12 Feb 2026

Numerical simulations using finite-element scheme for the optimization of micropolar tri-hybrid nanofluids with periodic gravitational disturbance and heat source/sink effects

in Fluid Dynamics

Rania Saadeh
Suad Alrebdi
A. M. Obalalu
Ayodeji Felix Isarinade
Umair Khan

Frontiers in Physics

doi 10.3389/fphy.2026.1740818

242 views

Methods

Published on 12 Feb 2026

Quantifying cytoskeletal protein interactions with far Western blotting

in Protein Biochemistry for Basic and Applied Sciences

Marcelo M. Melo
Elizabeth S. Phillippi
Mark L. Schultz
Susan Q. Shen
Hatem El-Shanti

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1761723

173 views

Original Research

Published on 12 Feb 2026

Dynamic C-reactive protein trajectories predict prolonged healing time in diabetic wounds: a machine learning model based on a single-center cohort with standardized wound size

in Pathology

Sichao Jiang
Qixuan Song
Junhuan Wang
Xiaohong Sun
Zhen Zhang
Shouyu Wang
Junwei Zong

Frontiers in Medicine

doi 10.3389/fmed.2026.1778003

124 views

Original Research

Published on 12 Feb 2026

Diagnostic performance of serum 14-3-3η protein versus conventional serological markers in early rheumatoid arthritis

in Inflammation

Tiantian Liu
Wenbin Guo

Frontiers in Immunology

doi 10.3389/fimmu.2026.1746239

105 views

Original Research

Published on 12 Feb 2026

Metrnl as a predictive biomarker for postprandial hypertriglyceridemia in overweight and obese populations

in Obesity

Xiaoyu Wang
Yale Tang
Shaojing Zeng
Luxuan Li
Yilin Hou
Dandan Liu
Peipei Tian
Guangyao Song

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1729571

154 views

Original Research

Published on 12 Feb 2026

Craving under pressure: the interplay between hedonic hunger, mental health, and ultra-processed food consumption in shift-workers

in Public Health and Nutrition

Elif Akin
Hatice Merve Bayram
Arda Ozturkcan

Frontiers in Public Health

doi 10.3389/fpubh.2026.1757016

156 views

Articles

A refined SMOTE-ENN optimization method based on machine learning for heart rate variability data classification

Comparative mediator analysis: establishing links between mathematical thinking and creativity through digital game addiction and violent tendencies across gifted and non-gifted student groups

Potential key factors? Exploring the predictive role and necessity of emotional intelligence and resilience for pre-service teachers’ critical thinking disposition

Prediction of treatment responsiveness to home-based transcranial photobiomodulation (tPBM) intervention for cognitive decline using fNIRS concurrently recorded during tPBM

Resveratrol reduces muscle atrophy and stress pathway activation in a combined disuse-hypoxia-mouse model

Moral decision-making in patients with neurodegenerative diseases: a systematic review

Retraining and control therapy: sense of control and catastrophic symptom expectations as targets of a cognitive behavioral treatment for pediatric functional seizures

mRNA vaccines transform personalized lung cancer treatment

A Treat-to-Target approach in hereditary angioedema: expert consensus from a European committee

Training requirements and associated factors for nursing assistants in Jiaxing City, China: a cross-sectional study in healthcare settings

Numerical simulations using finite-element scheme for the optimization of micropolar tri-hybrid nanofluids with periodic gravitational disturbance and heat source/sink effects

Quantifying cytoskeletal protein interactions with far Western blotting

Dynamic C-reactive protein trajectories predict prolonged healing time in diabetic wounds: a machine learning model based on a single-center cohort with standardized wound size

Diagnostic performance of serum 14-3-3η protein versus conventional serological markers in early rheumatoid arthritis

Metrnl as a predictive biomarker for postprandial hypertriglyceridemia in overweight and obese populations

Craving under pressure: the interplay between hedonic hunger, mental health, and ultra-processed food consumption in shift-workers