Library Design | List of Frontiers open access articles

Original Research

Published on 02 Dec 2022

Combinatorial library design for improving isobutanol production in Saccharomyces cerevisiae

in Synthetic Biology

Francesca V. Gambacorta
Joshua J. Dietrich
Justin J. Baerwald
Stephanie J. Brown
Yun Su
Brian F. Pfleger

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.1080024

5,515 views
7 citations

Original Research

Published on 10 Feb 2023

Mining the Protein Data Bank to inspire fragment library design

in Theoretical and Computational Chemistry

Julia Revillo Imbernon
Luca Chiesa
Esther Kellenberger

Frontiers in Chemistry

doi 10.3389/fchem.2023.1089714

6,608 views
3 citations

Original Research

Published on 13 Aug 2019

Identification of Novel 3-Hydroxy-pyran-4-One Derivatives as Potent HIV-1 Integrase Inhibitors Using in silico Structure-Based Combinatorial Library Design Approach

in Medicinal and Pharmaceutical Chemistry

Hajar Sirous
Giulia Chemi
Sandra Gemma
Stefania Butini
Zeger Debyser
Frauke Christ
Lotfollah Saghaie
Simone Brogi
Afshin Fassihi
Giuseppe Campiani

Frontiers in Chemistry

doi 10.3389/fchem.2019.00574

24,372 views
46 citations

Review

Published on 10 Feb 2026

PhIP-Seq: unveiling the complexity of antibody repertoires in health and disease

in Cancer Immunity and Immunotherapy

Wenjie Tang
Qijing Gai
Junjie Yang
Jianqing Chen
Zhengbing Lyu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1735735

391 views

Original Research

Published on 03 Aug 2022

Generation of synthetic antibody fragments with optimal complementarity determining region lengths for Notch-1 recognition

in Phage Biology

Bharathikumar Vellalore Maruthachalam
Kris Barreto
Daniel Hogan
Anthony Kusalik
Clarence Ronald Geyer

Frontiers in Microbiology

doi 10.3389/fmicb.2022.931307

4,141 views
4 citations

Original Research

Published on 28 Aug 2017

Molecular Connectivity Predefines Polypharmacology: Aliphatic Rings, Chirality, and sp3 Centers Enhance Target Selectivity

in Experimental Pharmacology and Drug Discovery

Stefania Monteleone
Julian E. Fuchs
Klaus R. Liedl

Frontiers in Pharmacology

doi 10.3389/fphar.2017.00552

6,569 views
24 citations

Original Research

Published on 11 Jul 2025

From motion to meaning: understanding students’ seating preferences in libraries through PIR-enabled machine learning and explainable AI

in Environmental Psychology

Gizem Izmir Tunahan
Goksu Tuysuzoglu
Hector Altamirano

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1642381

3,880 views
1 citation

Articles

Combinatorial library design for improving isobutanol production in Saccharomyces cerevisiae

Mining the Protein Data Bank to inspire fragment library design

Identification of Novel 3-Hydroxy-pyran-4-One Derivatives as Potent HIV-1 Integrase Inhibitors Using in silico Structure-Based Combinatorial Library Design Approach

PhIP-Seq: unveiling the complexity of antibody repertoires in health and disease

Generation of synthetic antibody fragments with optimal complementarity determining region lengths for Notch-1 recognition

Molecular Connectivity Predefines Polypharmacology: Aliphatic Rings, Chirality, and sp3 Centers Enhance Target Selectivity

From motion to meaning: understanding students’ seating preferences in libraries through PIR-enabled machine learning and explainable AI