Ligamentum Flavum | List of Frontiers open access articles

Case Report

Published on 10 Feb 2025

Case Report: Surgical treatment of lumbar ligamentum flavum cysts combined with spinal instability causing radiculopathy

in Orthopedic Surgery

Keshi Yang
Changbin Ji
Dawei Luo
Jiwei Yin
Xiaozhe Wu
Hui Xu

Frontiers in Surgery

doi 10.3389/fsurg.2025.1481216

1,848 views
1 citation

Systematic Review

Published on 09 Oct 2024

Transthyretin amyloidosis in patients with spinal stenosis who underwent spinal surgery: a systematic review and meta-analysis

in Neuroepidemiology

Domantas Tamasauskas
Laura Tamasauskiene

Frontiers in Neurology

doi 10.3389/fneur.2024.1425862

2,755 views
1 citation

Original Research

Published on 20 Oct 2025

Efficacy analysis of ligamentum flavum preservation technique under unilateral biportal endoscopic in the treatment of lumbar disc herniation

in Orthopedic Surgery

Wen-Bo Wei
Sha-Jie Dang
Ling Wei
Da-Peng Duan

Frontiers in Surgery

doi 10.3389/fsurg.2025.1627051

1,525 views

Original Research

Published on 26 Jan 2026

Precise localization value of lumbar lamina and ligamentum flavum boundaries in minimally invasive tubular resection of intraspinal schwannomas

in Neuro-Oncology and Neurosurgical Oncology

Longfei Shu
Yan Liu
Feihu Dai
Chunmei Chen
Yuhai Wang
Wei Zhao

Frontiers in Neurology

doi 10.3389/fneur.2025.1721714

536 views

Systematic Review

Published on 12 Apr 2021

Dysregulation of MicroRNAs in Hypertrophy and Ossification of Ligamentum Flavum: New Advances, Challenges, and Potential Directions

in RNA

Baoliang Zhang
Guanghui Chen
Xiaoxi Yang
Tianqi Fan
Xi Chen
Zhongqiang Chen

Frontiers in Genetics

doi 10.3389/fgene.2021.641575

5,435 views
16 citations

Original Research

Published on 18 Sep 2020

CRLF1 Is a Key Regulator in the Ligamentum Flavum Hypertrophy

in Molecular and Cellular Pathology

Zhenyu Zheng
Xiang Ao
Peng Li
Zhengnan Lian
Tao Jiang
Zhongmin Zhang
Liang Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2020.00858

8,971 views
37 citations

Review

Published on 31 Oct 2024

Pathogenesis of thoracic ossification of the ligamentum flavum

in Experimental Pharmacology and Drug Discovery

Chi Zhang
Yanan Chang
Li Shu
Zhongqiang Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1496297

9,265 views
12 citations

Original Research

Published on 12 Oct 2022

Analysis of the surgical strategy and postoperative clinical effect of thoracic ossification of ligament flavum with dural ossification

in Orthopedic Surgery

Tao Liu
Sidong Yang
Shuo Tian
Zhen Liu
Wenyuan Ding
Zheng Wang
Dalong Yang

Frontiers in Surgery

doi 10.3389/fsurg.2022.1036253

2,632 views
4 citations

Case Report

Published on 11 Jan 2023

Successful treatment of thoracic myelopathy caused by spontaneous spinal epidural hematoma (SSEH) combined with calcification of the ligamentum flavum (CLF) by posterior percutaneous endoscopic surgery (PPES): A case report

in Orthopedic Surgery

Hou Lisheng
Zhang Dong
Bai Xuedong
Shi Jinglei
Nan Shaokui
Gao Tianjun
Ge Feng
He Qing

Frontiers in Surgery

doi 10.3389/fsurg.2022.1077343

2,264 views
3 citations

Original Research

Published on 15 May 2025

Single-cell RNA-seq uncovers lineage-specific regulatory alterations of fibroblasts and endothelial cells in ligamentum flavum hypertrophy

in Inflammation

Yongxin Chen
Jue Zhang
Xincheng Feng
Qinghong Ma
Chao Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1569296

3,604 views

Case Report

Published on 22 Jan 2026

Uniportal non-coaxial endoscopic posterior cervical discectomy with annular suture repair for C6/C7 disc herniation: a case report

in Orthopedic Surgery

Yaoyu Xiang
Xin Zhang
Fei Sun
Xianguang Yang
Xidan Hu
Jing Yang
Weiqing Ge
Tao Zhou
Yixiao Wang
En Song

Frontiers in Surgery

doi 10.3389/fsurg.2025.1733374

540 views

Original Research

Published on 08 Aug 2022

The cervical sagittal curvature change in patients with or without PCSM after laminoplasty

in Orthopedic Surgery

Shengjun Qian
Zhan Wang
Ying Ren
Ian Chew
Guangyao Jiang
Wanli Li
Weishan Chen

Frontiers in Surgery

doi 10.3389/fsurg.2022.906839

2,564 views
3 citations

Original Research

Published on 16 Aug 2024

RMRP accelerates ligamentum flavum hypertrophy by regulating GSDMD-mediated pyroptosis through Gli1 SUMOylation

in Inflammation

Xudong Yan
Tinglong Liu
Run Zhang
Qinghong Ma
Chao Sun

Frontiers in Immunology

doi 10.3389/fimmu.2024.1427970

3,915 views
7 citations

Original Research

Published on 27 Sep 2022

Intraoperative neurophysiologic monitoring alteration during en bloc laminectomy surgery for thoracic ossification of ligamentum flavum

in Orthopedic Surgery

Xiaoning Feng
Li Deng
Haoyu Feng
Yong Hu
Jianghua Tian
Lin Sun

Frontiers in Surgery

doi 10.3389/fsurg.2022.1019112

3,039 views
8 citations

Original Research

Published on 16 Jan 2025

Innovative surgical and stress-stimulated rat model of ligamentum flavum hypertrophy

in Comparative and Clinical Medicine

Long Chen
Zhaoyuan Zhang
Niandong Li
Wanxia Zhang
Zhouhang Zheng
Yu Zhang

Frontiers in Veterinary Science

doi 10.3389/fvets.2024.1490769

1,678 views
2 citations

Perspective

Published on 28 Nov 2025

Ligamentum flavum hypertrophy animal models: methodological trade-offs and future directions

in Veterinary Clinical, Anatomical, and Comparative Pathology

Long Chen
Wanxia Zhang
Yu Zhang
Qin Gong

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1703252

937 views

Articles

Case Report: Surgical treatment of lumbar ligamentum flavum cysts combined with spinal instability causing radiculopathy

Transthyretin amyloidosis in patients with spinal stenosis who underwent spinal surgery: a systematic review and meta-analysis

Efficacy analysis of ligamentum flavum preservation technique under unilateral biportal endoscopic in the treatment of lumbar disc herniation

Precise localization value of lumbar lamina and ligamentum flavum boundaries in minimally invasive tubular resection of intraspinal schwannomas

Dysregulation of MicroRNAs in Hypertrophy and Ossification of Ligamentum Flavum: New Advances, Challenges, and Potential Directions

CRLF1 Is a Key Regulator in the Ligamentum Flavum Hypertrophy

Pathogenesis of thoracic ossification of the ligamentum flavum

Analysis of the surgical strategy and postoperative clinical effect of thoracic ossification of ligament flavum with dural ossification

Successful treatment of thoracic myelopathy caused by spontaneous spinal epidural hematoma (SSEH) combined with calcification of the ligamentum flavum (CLF) by posterior percutaneous endoscopic surgery (PPES): A case report

Single-cell RNA-seq uncovers lineage-specific regulatory alterations of fibroblasts and endothelial cells in ligamentum flavum hypertrophy

Uniportal non-coaxial endoscopic posterior cervical discectomy with annular suture repair for C6/C7 disc herniation: a case report

The cervical sagittal curvature change in patients with or without PCSM after laminoplasty

RMRP accelerates ligamentum flavum hypertrophy by regulating GSDMD-mediated pyroptosis through Gli1 SUMOylation

Intraoperative neurophysiologic monitoring alteration during en bloc laminectomy surgery for thoracic ossification of ligamentum flavum

Innovative surgical and stress-stimulated rat model of ligamentum flavum hypertrophy

Ligamentum flavum hypertrophy animal models: methodological trade-offs and future directions