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4 articles related to "Ligand Potency"

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Articles

Original Research

Published on 22 Dec 2015

Disturbances of Ligand Potency and Enhanced Degradation of the Human Glycine Receptor at Affected Positions G160 and T162 Originally Identified in Patients Suffering from Hyperekplexia

in Molecular Signalling and Pathways

Sinem Atak
Georg Langlhofer
Natascha Schaefer
Denise Kessler
Heike Meiselbach
Carolyn Delto
Hermann Schindelin
Carmen Villmann

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2015.00079

4,361 views
10 citations

Original Research

Published on 11 Oct 2023

In silico and in vitro study of bioactive compounds of Nigella sativa for targeting neuropilins in breast cancer

in Medicinal and Pharmaceutical Chemistry

Imran Zafar
Arfa Safder
Hassan Imran Afridi
Sania Riaz
Rizwan -ur-Rehman
Ahsanullah Unar
Fakhar Un Nisa
Abdel-Rhman Z. Gaafar
Mohammed Bourhia
Gezahign Fentahun Wondmie

Frontiers in Chemistry

doi 10.3389/fchem.2023.1273149

9,118 views
15 citations

Original Research

Published on 27 Mar 2025

Agonist efficacy at the β2AR is driven by the faster association rate of the Gs protein

in Experimental Pharmacology and Drug Discovery

Clare R. Harwood
David A. Sykes
Theo Redfern-Nichols
Owen Underwood
Colin Nicholson
Armin N. Khoshgrudi
Eline J. Koers
Graham Ladds
Stephen J. Briddon
Dmitry B. Veprintsev

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1367991

5,525 views
1 citation

Original Research

Published on 24 Apr 2018

Aromatic Rings Commonly Used in Medicinal Chemistry: Force Fields Comparison and Interactions With Water Toward the Design of New Chemical Entities

in Experimental Pharmacology and Drug Discovery

Marcelo D. Polêto
Victor H. Rusu
Bruno I. Grisci
Marcio Dorn
Roberto D. Lins
Hugo Verli

Frontiers in Pharmacology

doi 10.3389/fphar.2018.00395

55,080 views
55 citations