Obstacle Problem | List of Frontiers open access articles

Original Research

Published on 04 Mar 2026

Exploring the strengths and limitations of AI-driven variant prioritization versus manual curation in inborn errors of immunity

in Genetics of Common and Rare Diseases

Laith Ibrahim Moushib
Nerea Moreno-Ruiz
Andrea Martín-Nalda
Jacques G. Rivière
Blanca Urban
Romina Dieli-Crimi
Janire Perurena-Prieto
Aina Aguiló-Cucurull
Elena Pérez-Estévez
Xavier Solanich

Frontiers in Genetics

doi 10.3389/fgene.2026.1713299

147 views

Original Research

Published on 04 Mar 2026

Defects in PDIA4 increase individuals’ susceptibility to congenital heart disease

in Genetics of Common and Rare Diseases

Yuquan Lu
Jiangjie Liu
Siyu Sun
Zhiyu Feng
Yuan Gao
Shaojie Min
Quannan Zhuang
Siyi Lin
Quming Zhao
Xianghui Huang

Frontiers in Genetics

doi 10.3389/fgene.2026.1753969

258 views

Original Research

Published on 04 Mar 2026

Protective effects of Lagerstroemia speciosa against paracetamol-induced renal and testicular toxicity in rats via antioxidant, anti-inflammatory, and anti-apoptotic mechanisms

in Regulatory Toxicology

Nagham E. Elsheshtawy
Engy F. Risha
Fatma M. Abdelhamid
Bodour S. Rajab
Rehab Bagadood
Bayan Bokhari
Ghadir Sindi
Ahmed I. Ateya
Shaymaa Rezk
Mohamed E. El-Boshy

Frontiers in Toxicology

doi 10.3389/ftox.2026.1751678

216 views

Original Research

Published on 04 Mar 2026

Integrative biology shows DPP4 affects inflammatory response to eclampsia and cell model growth via p65/NLRP3/ASC/Caspase-1 pathway

in Immunogenetics

Zhimin Bian
Li Hao
Rongjuan Yang
Jianghui Sun

Frontiers in Genetics

doi 10.3389/fgene.2026.1775026

132 views

Case Report

Published on 04 Mar 2026

Co-occurring DMD, GJA1, and novel FYCO1 variants in a proband from a consanguineous oculodentodigital dysplasia family: a rare multi-locus case report

in Genetics of Common and Rare Diseases

Kondyarpu Abhishek
Nitish Kumar Mohanta
Joseph John
Swarupa Panda
Amit Kumar Satapathy
Roma Rattan
Puppala Venkat Ramchander

Frontiers in Genetics

doi 10.3389/fgene.2026.1753212

258 views

Original Research

Published on 04 Mar 2026

Pathways to meeting growing electricity demand through expanding customer choice: a review of emerging hybrid power choice policies and practices

in Energy and Society

Eric O'Shaughnessy
Jolie Villegas

Frontiers in Sustainable Energy Policy

doi 10.3389/fsuep.2026.1766514

Brief Research Report

Published on 04 Mar 2026

Identification of a novel HLA-G allele, HLA-G*01:66, using PolyseqOne and oxford nanopore sequencing

in Immunogenetics

Ran Li
Liyan Sun
Siqi Cai

Frontiers in Genetics

doi 10.3389/fgene.2026.1786514

Original Research

Accepted on 03 Mar 2026

Inferring an Ancestral Alginate Lyase for improved Stability and High-Level Expression Using Fed-Batch Fermentation

in Microbiotechnology

Hongxiao Mu
Renquan Guo
Beichen Zhao
Zhuang Huang
Mingda Lei
Lei Lei
Jun Liu
Xing Wang
Zhenggang Xie

Frontiers in Microbiology

Original Research

Accepted on 03 Mar 2026

Prim-O-glucosylcimifugin ameliorates DSS-induced ulcerative colitis via suppressing NLRP3 inflammasome activation

in Experimental Pharmacology and Drug Discovery

Fuqian Wang
Xin Xiong
Qingfeng Ruan
Dan Zhang
Chuanqi Huang
Tingting Xie
LU CHENG

Frontiers in Pharmacology

Original Research

Accepted on 03 Mar 2026

Bond and Flexural Strength of Industrial Cast UHPFRC-NC Deck in Norway

in Construction Materials

Malena Thomassen
Ingrid Lande

Frontiers in Built Environment

Original Research

Accepted on 03 Mar 2026

Political and Intellectual Legacy of Nikolai Ivanovich Astrov in Russia and in Emigration

in Sociological Theory

Larisa Orchakova
Yuliya Smirnova
Elena Tokareva

Frontiers in Sociology

Original Research

Accepted on 03 Mar 2026

Μaternal and Neonatal Vitamin D Metabolite Profiling and Its Long-Term Impact on Childhood Growth: Findings from the KLOTHO Birth Cohort

in Reproduction

Spyridon N Karras
Dimitrios G. Goulis
Maria Kypraiou
Vikentia Harizopoulou
Antonios Vlastos
Marios Anemoulis
Georgios Tzimagiorgis
Maria Dalamaga
Neoklis Georgopoulos
Eva Kassi

Frontiers in Endocrinology

Original Research

Accepted on 03 Mar 2026

Emergence of tet(X4) and blaNDM-5 in Clinical Isolates of Salmonella Typhimurium 1,4,[5],12:i:- from Jinhua, China: Epidemiological and Genomic Characterization

in Infectious Agents and Disease

Chen Yang
Shuying Zhu
Zhifeng Pang
Bin Wu
Junliang Wu
Jingchao Shi

Frontiers in Microbiology

Editorial

Accepted on 03 Mar 2026

Editorial: Advances in Molecular Genetics of Marfan Syndrome and Related Disorders

in Human and Medical Genomics

Georgia Damoraki

Frontiers in Genetics

Original Research

Accepted on 03 Mar 2026

Long Non-Coding RNA TGFB2-OT1 as a Diagnostic Biomarker and ceRNA Regulator in Rheumatoid Arthritis

in Human and Medical Genomics

Yuqun Wang
Liu Junhong
Linping Du
Xiaodong Wang
Yuhua Su

Frontiers in Genetics

Original Research

Accepted on 03 Mar 2026

Imaging Photoplethysmography Reveals Differences in the Reactions of Cerebral and Systemic Hemodynamics to Infusion of Vasoactive Drugs

in Vascular Physiology

Alexey Y. Sokolov
Valeriy Victorovich Zaytsev
Anton V. Shcherbinin
Alexei A. Kamshilin

Frontiers in Physiology

Articles

Exploring the strengths and limitations of AI-driven variant prioritization versus manual curation in inborn errors of immunity

Defects in PDIA4 increase individuals’ susceptibility to congenital heart disease

Protective effects of Lagerstroemia speciosa against paracetamol-induced renal and testicular toxicity in rats via antioxidant, anti-inflammatory, and anti-apoptotic mechanisms

Integrative biology shows DPP4 affects inflammatory response to eclampsia and cell model growth via p65/NLRP3/ASC/Caspase-1 pathway

Co-occurring DMD, GJA1, and novel FYCO1 variants in a proband from a consanguineous oculodentodigital dysplasia family: a rare multi-locus case report

Pathways to meeting growing electricity demand through expanding customer choice: a review of emerging hybrid power choice policies and practices

Identification of a novel HLA-G allele, HLA-G*01:66, using PolyseqOne and oxford nanopore sequencing

Inferring an Ancestral Alginate Lyase for improved Stability and High-Level Expression Using Fed-Batch Fermentation

Prim-O-glucosylcimifugin ameliorates DSS-induced ulcerative colitis via suppressing NLRP3 inflammasome activation

Bond and Flexural Strength of Industrial Cast UHPFRC-NC Deck in Norway

Political and Intellectual Legacy of Nikolai Ivanovich Astrov in Russia and in Emigration

Μaternal and Neonatal Vitamin D Metabolite Profiling and Its Long-Term Impact on Childhood Growth: Findings from the KLOTHO Birth Cohort

Emergence of tet(X4) and blaNDM-5 in Clinical Isolates of Salmonella Typhimurium 1,4,[5],12:i:- from Jinhua, China: Epidemiological and Genomic Characterization

Editorial: Advances in Molecular Genetics of Marfan Syndrome and Related Disorders

Long Non-Coding RNA TGFB2-OT1 as a Diagnostic Biomarker and ceRNA Regulator in Rheumatoid Arthritis

Imaging Photoplethysmography Reveals Differences in the Reactions of Cerebral and Systemic Hemodynamics to Infusion of Vasoactive Drugs