Optimal System | List of Frontiers open access articles

Original Research

Published on 04 Mar 2026

Artificial neural network-based immune biomarker signature predicts pathological complete response to neoadjuvant chemotherapy in HER2-negative breast cancer

in Cancer Immunity and Immunotherapy

Yulong Zhang
Shitang Nong
Suai Deng
Qiyuan Su
Jiao Lu
Dalang Fang
Shihuan Qin
Yanfei Ma

Frontiers in Oncology

doi 10.3389/fonc.2026.1781380

Core Concept

Published on 04 Mar 2026

Towards SDG 5—Giving Girls and Women Better Lives By Fixing Water Problems

in Earth Sciences

Shouq Alshahrani
Yoshihide Wada

Frontiers for Young Minds

doi 10.3389/frym.2026.1705202

Systematic Review

Published on 04 Mar 2026

Effectiveness and safety of auricular therapy for polycystic ovary syndrome: a systematic review and meta-analysis

in Reproduction

Xi Li
Shuang Xu
Liangzhen Xie
Hongying Kuang
Jialing Liu
Yan Li

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1726938

157 views

Original Research

Published on 04 Mar 2026

Clinical characteristics and prognostic factors of Clostridium perfringens infection complicated by massive intravascular hemolysis in patients with hematologic diseases: a retrospective case series study

in Hematology

Weixiang Lin
Juan Feng
Zhihong Fang

Frontiers in Medicine

doi 10.3389/fmed.2026.1726461

Review

Published on 04 Mar 2026

The roles of folate, MTHFR genetics, vitamin B12 in pregnancy outcomes

in Clinical Nutrition

Ruihua Yang
Guanghui Li

Frontiers in Nutrition

doi 10.3389/fnut.2026.1785263

Original Research

Published on 04 Mar 2026

Impact of nitrogen fertilizer concentrations on growth, yield, and nutrient use efficiency of wolfberry (Lycium barbarum L.) in Northwestern China

in Plant Nutrition

Mengfei Yuan
Ligang Xu
Jiaxuan Dou
Ying Tang
Xue Tan
Wangbo Xu

Frontiers in Plant Science

doi 10.3389/fpls.2026.1787344

Clinical Trial

Published on 04 Mar 2026

Singing as training modality within pulmonary rehabilitation for COPD patients may enhance diaphragmatic function: a pilot RCT exploring impact on diaphragmatic mobility and thickness

in Exercise Physiology

Daozheng Lv
Zhengtong Qiao
Jiazhen Zhang
Jiayu Xin
Kai Liu

Frontiers in Physiology

doi 10.3389/fphys.2026.1728597

232 views

Original Research

Published on 04 Mar 2026

Identification of gemilukast as a bifunctional molecule with lipid-lowering and anti-inflammatory activities

in Inflammation

Yuanyuan Liu
Yixiao Wang
Rufei Wang
Qingshan Yang
Guojun Pan
Renshuai Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1738104

Original Research

Published on 04 Mar 2026

A physical-environment-driven multi-stream deep neural network for short-term heavy precipitation potential identification

in Climate Monitoring

Jie Liu
Jingjing An
Chen Yao
Zhaoye Wu
Huimin Li
Xiaoye Zhou
Gaoping Liu
Ruijiao Wu

Frontiers in Climate

doi 10.3389/fclim.2026.1776202

Original Research

Published on 04 Mar 2026

Academic stressors and coping strategies among MBBS students: a cross-sectional, year-wise comparative study

in Healthcare Professions Education

Priyanka Rathi
Keshav Banga
Himanshu Singh

Frontiers in Medicine

doi 10.3389/fmed.2026.1789919

Case Report

Published on 04 Mar 2026

Case report: Carcinoma en cuirasse—widespread cutaneous metastases from breast adenocarcinoma

in Breast Cancer

Chongyi Wei
Jianping Long
Tao Yang
Haicun Zhou
Xiaoke Chai

Frontiers in Oncology

doi 10.3389/fonc.2026.1742907

Original Research

Published on 04 Mar 2026

Immunoreactivity of pan MHC-I epitopes on Crimean-Congo hemorrhagic fever virus glycoprotein C-terminal

in Viral Immunology

Dongbo Jiang
Yongkai Wang
Haobo Kang
Zhenchi Fang
Jianchang Li
Zilu Ma
Yubo Sun
Yanbo Wang
Zhihe Fu
Yulin Yang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1693892

147 views

Original Research

Published on 04 Mar 2026

Building digital competence for future healthcare through hands-on AI experience

in Digital Education

Yngve Røe
Marko Lukic
Safora Johansen
Wilfried Admiraal
Minna Pikkarainen

Frontiers in Education

doi 10.3389/feduc.2026.1752683

113 views

Original Research

Published on 04 Mar 2026

Self-experienced empathetic behaviour patterns in medical students during virtual patient encounters: a comparison between an AI-enhanced social robot and a computer-based platform

in AI for Human Learning and Behavior Change

Alexander Borg
Benjamin Jobs
Cidem Gentline
Viking Huss
Anna Hugelius
Jonathan Schiött
William Ivegren
Fabricio Espinosa
Mini Ruiz
Samuel Edelbring

Frontiers in Artificial Intelligence

doi 10.3389/frai.2026.1795842

Original Research

Published on 04 Mar 2026

Correlation between anemia-related red blood cell parameters and pulmonary function severity in patients with AECOPD

in Pulmonary Medicine

Hui Dou
Jichen Qiao
Hailian Zhang
Dabang Cai
Cheng Meng
Xin Wei
Linghua Cui
Shumei Shao
Lei Lv

Frontiers in Medicine

doi 10.3389/fmed.2026.1773007

Case Report

Published on 04 Mar 2026

Case Report: A 69-year-old woman with dermatopathic lymphadenopathy and hypercalcemia after COVID-19 infection

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Danli Hu
Yanchun Li
Shen Shen

Frontiers in Immunology

doi 10.3389/fimmu.2026.1702218

Articles

Artificial neural network-based immune biomarker signature predicts pathological complete response to neoadjuvant chemotherapy in HER2-negative breast cancer

Towards SDG 5—Giving Girls and Women Better Lives By Fixing Water Problems

Effectiveness and safety of auricular therapy for polycystic ovary syndrome: a systematic review and meta-analysis

Clinical characteristics and prognostic factors of Clostridium perfringens infection complicated by massive intravascular hemolysis in patients with hematologic diseases: a retrospective case series study

The roles of folate, MTHFR genetics, vitamin B12 in pregnancy outcomes

Impact of nitrogen fertilizer concentrations on growth, yield, and nutrient use efficiency of wolfberry (Lycium barbarum L.) in Northwestern China

Singing as training modality within pulmonary rehabilitation for COPD patients may enhance diaphragmatic function: a pilot RCT exploring impact on diaphragmatic mobility and thickness

Identification of gemilukast as a bifunctional molecule with lipid-lowering and anti-inflammatory activities

A physical-environment-driven multi-stream deep neural network for short-term heavy precipitation potential identification

Academic stressors and coping strategies among MBBS students: a cross-sectional, year-wise comparative study

Case report: Carcinoma en cuirasse—widespread cutaneous metastases from breast adenocarcinoma

Immunoreactivity of pan MHC-I epitopes on Crimean-Congo hemorrhagic fever virus glycoprotein C-terminal

Building digital competence for future healthcare through hands-on AI experience

Self-experienced empathetic behaviour patterns in medical students during virtual patient encounters: a comparison between an AI-enhanced social robot and a computer-based platform

Correlation between anemia-related red blood cell parameters and pulmonary function severity in patients with AECOPD

Case Report: A 69-year-old woman with dermatopathic lymphadenopathy and hypercalcemia after COVID-19 infection