Partial Agonism | List of Frontiers open access articles

Original Research

Published on 19 Sep 2018

Synthesis, Biological Evaluation, and SAR Studies of 14β-phenylacetyl Substituted 17-cyclopropylmethyl-7, 8-dihydronoroxymorphinones Derivatives: Ligands With Mixed NOP and Opioid Receptor Profile

in Psychopharmacology

Vinod Kumar
Willma E. Polgar
Gerta Cami-Kobeci
Mark P. Thomas
Taline V. Khroyan
Lawrence Toll
Stephen M. Husbands

Frontiers in Psychiatry

doi 10.3389/fpsyt.2018.00430

4,698 views
3 citations

Original Research

Published on 17 Jan 2022

Quantifying the Kinetics of Signaling and Arrestin Recruitment by Nervous System G-Protein Coupled Receptors

in Cellular Neurophysiology

Sam R. J. Hoare
Paul H. Tewson
Shivani Sachdev
Mark Connor
Thomas E. Hughes
Anne Marie Quinn

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2021.814547

9,249 views
17 citations

Review

Published on 22 Apr 2024

A review on the pharmacology of cariprazine and its role in the treatment of negative symptoms of schizophrenia

in Schizophrenia

Panneer Selvan
Prashant Devkare
Arthik Shetty
Shruti Dharmadhikari
Chintan Khandhedia
Amey Mane
Suyog Mehta
Chittaranjan Andrade

Frontiers in Psychiatry

doi 10.3389/fpsyt.2024.1385925

17,060 views
14 citations

Original Research

Published on 07 May 2019

Ligand Binding Induces Agonistic-Like Conformational Adaptations in Helix 12 of Progesterone Receptor Ligand Binding Domain

in Theoretical and Computational Chemistry

Liangzhen Zheng
Kelin Xia
Yuguang Mu

Frontiers in Chemistry

doi 10.3389/fchem.2019.00315

5,077 views
9 citations

Perspective

Published on 16 Dec 2021

Partial Agonists and Dual Disorders: Focus on Dual Schizophrenia

in Psychopharmacology

Lola Peris
Nestor Szerman

Frontiers in Psychiatry

doi 10.3389/fpsyt.2021.769623

7,246 views
12 citations

Original Research

Published on 15 Dec 2023

Quantitative receptor model for responses that are left- or right-shifted versus occupancy (are more or less concentration sensitive): the SABRE approach

in Experimental Pharmacology and Drug Discovery

Peter Buchwald

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1274065

2,989 views
5 citations

Original Research

Published on 22 May 2017

Behavioral Effects of a Novel Benzofuranyl-Piperazine Serotonin-2C Receptor Agonist Suggest a Potential Therapeutic Application in the Treatment of Obsessive–Compulsive Disorder

in Psychopharmacology

Michelle M. Rodriguez
Carl Overshiner
J. David Leander
Xia Li
Denise Morrow
Richard G. Conway
David L. Nelson
Karin Briner
Jeffrey M. Witkin

Frontiers in Psychiatry

doi 10.3389/fpsyt.2017.00089

5,374 views
12 citations

Original Research

Published on 20 Nov 2018

Cannabinoid Receptor 2 Signalling Bias Elicited by 2,4,6-Trisubstituted 1,3,5-Triazines

in Experimental Pharmacology and Drug Discovery

Caitlin R. M. Oyagawa
Sara M. de la Harpe
Yurii Saroz
Michelle Glass
Andrea J. Vernall
Natasha Lillia Grimsey

Frontiers in Pharmacology

doi 10.3389/fphar.2018.01202

9,956 views
27 citations

Original Research

Published on 30 May 2023

Investigation of adenosine A1 receptor-mediated β-arrestin 2 recruitment using a split-luciferase assay

in Experimental Pharmacology and Drug Discovery

Luisa Saecker
Hanns Häberlein
Sebastian Franken

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1172551

5,470 views
8 citations

Articles

Synthesis, Biological Evaluation, and SAR Studies of 14β-phenylacetyl Substituted 17-cyclopropylmethyl-7, 8-dihydronoroxymorphinones Derivatives: Ligands With Mixed NOP and Opioid Receptor Profile

Quantifying the Kinetics of Signaling and Arrestin Recruitment by Nervous System G-Protein Coupled Receptors

A review on the pharmacology of cariprazine and its role in the treatment of negative symptoms of schizophrenia

Ligand Binding Induces Agonistic-Like Conformational Adaptations in Helix 12 of Progesterone Receptor Ligand Binding Domain

Partial Agonists and Dual Disorders: Focus on Dual Schizophrenia

Quantitative receptor model for responses that are left- or right-shifted versus occupancy (are more or less concentration sensitive): the SABRE approach

Behavioral Effects of a Novel Benzofuranyl-Piperazine Serotonin-2C Receptor Agonist Suggest a Potential Therapeutic Application in the Treatment of Obsessive–Compulsive Disorder

Cannabinoid Receptor 2 Signalling Bias Elicited by 2,4,6-Trisubstituted 1,3,5-Triazines

Investigation of adenosine A1 receptor-mediated β-arrestin 2 recruitment using a split-luciferase assay