Pde4b | List of Frontiers open access articles

Original Research

Published on 16 Dec 2021

PDE4B Induces Epithelial-to-Mesenchymal Transition in Bladder Cancer Cells and Is Transcriptionally Suppressed by CBX7

in Cell Adhesion and Migration

Zhengnan Huang
Jiakuan Liu
Jiale Yang
Yilin Yan
Chenkai Yang
Xiao He
Ruimin Huang
Mingyue Tan
Denglong Wu
Jun Yan

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.783050

4,949 views
19 citations

Original Research

Published on 12 Jan 2022

PDE4B Proposed as a High Myopia Susceptibility Gene in Chinese Population

in Human and Medical Genomics

Fuxin Zhao
Wei Chen
Hui Zhou
Peter S. Reinach
Yuhan Wang
Suh-Hang H. Juo
Zhenglin Yang
Anquan Xue
Yi Shi
Chung-Ling Liang

Frontiers in Genetics

doi 10.3389/fgene.2021.775797

7,982 views
9 citations

Original Research

Published on 03 Feb 2025

Rutaecarpine alleviates hepatic ischemia‒reperfusion injury in liver transplantation by inhibiting inflammatory response and oxidative stress

in Gastrointestinal and Hepatic Pharmacology

Yan Liu
Feng Qi
Lun-Jian Xiang
Zhu-Jun Yi
Sheng-Wei Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1539744

2,321 views
1 citation

Brief Research Report

Published on 21 Mar 2022

PDE4B Is a Homeostatic Regulator of Cyclic AMP in Dendritic Cells

in Inflammation Pharmacology

Amy M. Chinn
Cristina Salmerón
Jihyung Lee
Krishna Sriram
Eyal Raz
Paul A. Insel

Frontiers in Pharmacology

doi 10.3389/fphar.2022.833832

5,406 views
11 citations

Original Research

Published on 11 May 2018

A Novel Catecholopyrimidine Based Small Molecule PDE4B Inhibitor Suppresses Inflammatory Cytokines in Atopic Mice

in Experimental Pharmacology and Drug Discovery

Baskaran Purushothaman
Parthasarathy Arumugam
Joon Myong Song

Frontiers in Pharmacology

doi 10.3389/fphar.2018.00485

5,515 views
21 citations

Review

Published on 08 Feb 2019

Genetic Association of Phosphodiesterases With Human Cognitive Performance

in Molecular Signalling and Pathways

Mark E. Gurney

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2019.00022

8,360 views
23 citations

Original Research

Published on 18 Feb 2026

Nerandomilast attenuates idiopathic inflammatory myopathy-associated interstitial lung disease via inhibiting proliferation and differentiation of B cells

in Inflammation

Yuming Liu
Yayue Hu
Se-rigeleng
Zhongyi Yang
Xueze Liu
Jiayang Yu
Huihui Li
Songtao Gu
Weitao Yang
Cheng Yang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1771007

476 views

Original Research

Published on 09 Nov 2020

Therapeutic Potential of Triptolide as an Anti-Inflammatory Agent in Dextran Sulfate Sodium-Induced Murine Experimental Colitis

in Inflammation

Bufu Tang
Jinyu Zhu
Baohui Zhang
Fazong Wu
Yajie Wang
Qiaoyou Weng
Shiji Fang
Liyun Zheng
Yang Yang
Rongfang Qiu

Frontiers in Immunology

doi 10.3389/fimmu.2020.592084

13,732 views
64 citations

Original Research

Published on 22 Jan 2020

Identification of a Selective PDE4B Inhibitor From Bryophyllum pinnatum by Target Fishing Study and In Vitro Evaluation of Quercetin 3-O-α-L-Arabinopyranosyl-(1→2)-O-α-L-Rhamnopyranoside

in Experimental Pharmacology and Drug Discovery

Estela M. G. Lourenço
Júlia M. Fernandes
Vinícius de F. Carvalho
Raphael Grougnet
Marco A. Martins
Alessandro K. Jordão
Silvana M. Zucolotto
Euzébio G. Barbosa

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01582

6,660 views
21 citations

Original Research

Published on 03 Dec 2024

Menisoxoisoaporphine A, a novel oxoisoaporphine alkaloid from Menispermi Rhizoma, inhibits inflammation by targeting PDE4B

in Ethnopharmacology

Xin Qiao
Xiaojuan Cao
Shuang Xu
Cunlin Wang
Rui Guo
Xiaojuan Yao
Qiong Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1505116

2,411 views

Review

Published on 06 Oct 2022

The regulatory role of PDE4B in the progression of inflammatory function study

in Inflammation Pharmacology

Yue Su
Jiaxiang Ding
Fan Yang
Cuixia He
Yuanyuan Xu
Xingyu Zhu
Huan Zhou
Hongtao Li

Frontiers in Pharmacology

doi 10.3389/fphar.2022.982130

10,732 views
47 citations

Original Research

Published on 20 Apr 2022

BI 1015550 is a PDE4B Inhibitor and a Clinical Drug Candidate for the Oral Treatment of Idiopathic Pulmonary Fibrosis

in Inflammation Pharmacology

Franziska Elena Herrmann
Christian Hesslinger
Lutz Wollin
Peter Nickolaus

Frontiers in Pharmacology

doi 10.3389/fphar.2022.838449

60,830 views
110 citations

Correction

Published on 30 May 2023

Corrigendum: BI 1015550 is a PDE4B inhibitor and a clinical drug candidate for the oral treatment of idiopathic pulmonary fibrosis

in Inflammation Pharmacology

Franziska Elena Herrmann
Christian Hesslinger
Lutz Wollin
Peter Nickolaus

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1219760

4,217 views
9 citations

Original Research

Published on 26 Jul 2022

LncRNA GAS5 Knockdown Mitigates Hepatic Lipid Accumulation via Regulating MiR-26a-5p/PDE4B to Activate cAMP/CREB Pathway

in Obesity

Shizan Xu
Yajie Wang
Zhengyang Li
Qian Hua
Miao Jiang
Xiaoming Fan

Frontiers in Endocrinology

doi 10.3389/fendo.2022.889858

5,973 views
34 citations

Original Research

Published on 20 Nov 2020

Mapping Phosphodiesterase 4D (PDE4D) in Macaque Dorsolateral Prefrontal Cortex: Postsynaptic Compartmentalization in Layer III Pyramidal Cell Circuits

Dibyadeep Datta
John F. Enwright
Dominique Arion
Constantinos D. Paspalas
Yury M. Morozov
David A. Lewis
Amy F. T. Arnsten

Frontiers in Neuroanatomy

doi 10.3389/fnana.2020.578483

6,818 views
25 citations

Original Research

Published on 04 Jan 2022

Gene Co-Expression Network Analysis Identifies Vitamin D-Associated Gene Modules in Adult Normal Rectal Epithelium Following Supplementation

in Human and Medical Genomics

James P. Blackmur
Peter G. Vaughan-Shaw
Kevin Donnelly
Bradley T. Harris
Victoria Svinti
Anna-Maria Ochocka-Fox
Paz Freile
Marion Walker
Toby Gurran
Stuart Reid

Frontiers in Genetics

doi 10.3389/fgene.2021.783970

4,544 views
4 citations

Articles

PDE4B Induces Epithelial-to-Mesenchymal Transition in Bladder Cancer Cells and Is Transcriptionally Suppressed by CBX7

PDE4B Proposed as a High Myopia Susceptibility Gene in Chinese Population

Rutaecarpine alleviates hepatic ischemia‒reperfusion injury in liver transplantation by inhibiting inflammatory response and oxidative stress

PDE4B Is a Homeostatic Regulator of Cyclic AMP in Dendritic Cells

A Novel Catecholopyrimidine Based Small Molecule PDE4B Inhibitor Suppresses Inflammatory Cytokines in Atopic Mice

Genetic Association of Phosphodiesterases With Human Cognitive Performance

Nerandomilast attenuates idiopathic inflammatory myopathy-associated interstitial lung disease via inhibiting proliferation and differentiation of B cells

Therapeutic Potential of Triptolide as an Anti-Inflammatory Agent in Dextran Sulfate Sodium-Induced Murine Experimental Colitis

Identification of a Selective PDE4B Inhibitor From Bryophyllum pinnatum by Target Fishing Study and In Vitro Evaluation of Quercetin 3-O-α-L-Arabinopyranosyl-(1→2)-O-α-L-Rhamnopyranoside

Menisoxoisoaporphine A, a novel oxoisoaporphine alkaloid from Menispermi Rhizoma, inhibits inflammation by targeting PDE4B

The regulatory role of PDE4B in the progression of inflammatory function study

BI 1015550 is a PDE4B Inhibitor and a Clinical Drug Candidate for the Oral Treatment of Idiopathic Pulmonary Fibrosis

Corrigendum: BI 1015550 is a PDE4B inhibitor and a clinical drug candidate for the oral treatment of idiopathic pulmonary fibrosis

LncRNA GAS5 Knockdown Mitigates Hepatic Lipid Accumulation via Regulating MiR-26a-5p/PDE4B to Activate cAMP/CREB Pathway

Mapping Phosphodiesterase 4D (PDE4D) in Macaque Dorsolateral Prefrontal Cortex: Postsynaptic Compartmentalization in Layer III Pyramidal Cell Circuits

Gene Co-Expression Network Analysis Identifies Vitamin D-Associated Gene Modules in Adult Normal Rectal Epithelium Following Supplementation