Plx5622 | List of Frontiers open access articles

Original Research

Published on 25 Mar 2022

PLX5622 Reduces Disease Severity in Lethal CNS Infection by Off-Target Inhibition of Peripheral Inflammatory Monocyte Production

in Multiple Sclerosis and Neuroimmunology

Alanna G. Spiteri
Duan Ni
Zheng Lung Ling
Laurence Macia
Iain L. Campbell
Markus J. Hofer
Nicholas J. C. King

Frontiers in Immunology

doi 10.3389/fimmu.2022.851556

15,797 views
64 citations

Original Research

Published on 26 Mar 2021

Inflammatory Foreign Body Response Induced by Neuro-Implants in Rat Cortices Depleted of Resident Microglia by a CSF1R Inhibitor and Its Implications

in Neural Technology

Aviv Sharon
Maciej M. Jankowski
Nava Shmoel
Hadas Erez
Micha E. Spira

Frontiers in Neuroscience

doi 10.3389/fnins.2021.646914

8,605 views
22 citations

Review

Published on 02 Jul 2024

Microglia depletion leads to increased susceptibility to ocular hypertension-dependent glaucoma

in Neuroinflammation and Neuropathy

Cory A. Diemler
Michael MacLean
Sarah E. Heuer
Amanda A. Hewes
Olivia J. Marola
Richard T. Libby
Gareth R. Howell

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1396443

5,337 views
21 citations

Original Research

Published on 26 May 2023

Essential role of microglia in the fast antidepressant action of ketamine and hypidone hydrochloride (YL-0919)

in Neuropharmacology

Hai-Xia Chang
Wei Dai
Jin-Hao Bao
Jin-Feng Li
Ji-Guo Zhang
Yun-Feng Li

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1122541

6,566 views
6 citations

Original Research

Published on 28 Oct 2022

Microglia shield the murine brain from damage mediated by the cytokines IL-6 and IFN-α

in Cytokines and Soluble Mediators in Immunity

Phillip K. West
Barney Viengkhou
Iain L. Campbell
Markus J. Hofer

Frontiers in Immunology

doi 10.3389/fimmu.2022.1036799

8,233 views
16 citations

Original Research

Published on 23 Aug 2023

Myeloid-specific blockade of notch signaling alleviates dopaminergic neurodegeneration in Parkinson’s disease by dominantly regulating resident microglia activation through NF-κB signaling

in Immunological Tolerance and Regulation

Shi-Qian Liang
Peng-Hui Li
Yi-Yang Hu
Jun-Long Zhao
Fang-Ze Shao
Fang Kuang
Kai-Xi Ren
Tiao-Xia Wei
Fan Fan
Lei Feng

Frontiers in Immunology

doi 10.3389/fimmu.2023.1193081

6,185 views
12 citations

Articles

PLX5622 Reduces Disease Severity in Lethal CNS Infection by Off-Target Inhibition of Peripheral Inflammatory Monocyte Production

Inflammatory Foreign Body Response Induced by Neuro-Implants in Rat Cortices Depleted of Resident Microglia by a CSF1R Inhibitor and Its Implications

Microglia depletion leads to increased susceptibility to ocular hypertension-dependent glaucoma

Essential role of microglia in the fast antidepressant action of ketamine and hypidone hydrochloride (YL-0919)

Microglia shield the murine brain from damage mediated by the cytokines IL-6 and IFN-α

Myeloid-specific blockade of notch signaling alleviates dopaminergic neurodegeneration in Parkinson’s disease by dominantly regulating resident microglia activation through NF-κB signaling