Review
Published on 05 Jun 2020
Transgenic Rabbit Models in Proarrhythmia Research
in Cardiovascular and Smooth Muscle Pharmacology
Frontiers in Pharmacology
doi 10.3389/fphar.2020.00853
- 6,990 views
- 11 citations
32 articles related to "Proarrhythmia"
Articles
Original Research
Published on 05 Oct 2022
Cross clinical-experimental-computational qualification of in silico drug trials on human cardiac purkinje cells for proarrhythmia risk prediction
in In Vitro Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2022.992650
- 9,216 views
- 13 citations
Original Research
Published on 23 Aug 2017
Optimization of an In silico Cardiac Cell Model for Proarrhythmia Risk Assessment
in Computational Physiology and Medicine
Frontiers in Physiology
doi 10.3389/fphys.2017.00616
- 15,287 views
- 185 citations
Original Research
Published on 21 Sep 2017
The Effects of SEA0400 on Ca2+ Transient Amplitude and Proarrhythmia Depend on the Na+/Ca2+ Exchanger Expression Level in Murine Models
in Cardiovascular and Smooth Muscle Pharmacology
Frontiers in Pharmacology
doi 10.3389/fphar.2017.00649
- 5,115 views
- 10 citations
Original Research
Published on 06 May 2020
Inhibition of KCa2 and Kv11.1 Channels in Pigs With Left Ventricular Dysfunction
in Pharmacology of Ion Channels and Channelopathies
Frontiers in Pharmacology
doi 10.3389/fphar.2020.00556
- 2,858 views
- 2 citations
Original Research
Published on 21 Nov 2017
Uncertainty Quantification Reveals the Importance of Data Variability and Experimental Design Considerations for in Silico Proarrhythmia Risk Assessment
in Computational Physiology and Medicine
Frontiers in Physiology
doi 10.3389/fphys.2017.00917
- 11,426 views
- 97 citations
Correction
Published on 06 Dec 2017
Corrigendum: Optimization of an In silico Cardiac Cell Model for Proarrhythmia Risk Assessment
in Computational Physiology and Medicine
Frontiers in Physiology
doi 10.3389/fphys.2017.01025
- 2,428 views
- 8 citations
Methods
Published on 11 Oct 2017
An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes
in Cardiac Electrophysiology
Frontiers in Physiology
doi 10.3389/fphys.2017.00766
- 11,392 views
- 74 citations
Original Research
Published on 12 May 2023
Proarrhythmia associated with antiarrhythmic drugs: a comprehensive disproportionality analysis of the FDA adverse event reporting system
in Cardiovascular and Smooth Muscle Pharmacology
Frontiers in Pharmacology
doi 10.3389/fphar.2023.1170039
- 6,375 views
- 17 citations
Original Research
Published on 28 May 2024
Loss of protein phosphatase 2A regulatory subunit PPP2R5A is associated with increased incidence of stress-induced proarrhythmia
in Cardiac Rhythmology
Frontiers in Cardiovascular Medicine
doi 10.3389/fcvm.2024.1419597
- 2,307 views
- 1 citation
Original Research
Published on 10 Nov 2025
Towards human cardiac new approach methodologies (NAMs) to evaluate the combination of repolarization prolonging and shortening drugs: a pilot study
in Cardiovascular and Hematologic Drugs
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1679626
- 1,754 views
- 3 citations
Brief Research Report
Published on 22 Feb 2024
Divergent electrophysiologic action of dapagliflozin and empagliflozin on ventricular and atrial tachyarrhythmias in isolated rabbit hearts
in Cardiac Rhythmology
Frontiers in Cardiovascular Medicine
doi 10.3389/fcvm.2024.1369250
- 4,338 views
- 3 citations
Original Research
Published on 02 Feb 2021
Proarrhythmic Electrical Remodeling by Noncardiomyocytes at Interfaces With Cardiomyocytes Under Oxidative Stress
in Cardiac Electrophysiology
Frontiers in Physiology
doi 10.3389/fphys.2020.622613
- 3,976 views
- 6 citations
Original Research
Published on 04 Apr 2024
Evaluation of cardiac pro-arrhythmic risks using the artificial neural network with ToR–ORd in silico model output
in Computational Physiology and Medicine
Frontiers in Physiology
doi 10.3389/fphys.2024.1374355
- 2,451 views
- 5 citations
Original Research
Published on 19 Jan 2018
A Hybrid Model for Safety Pharmacology on an Automated Patch Clamp Platform: Using Dynamic Clamp to Join iPSC-Derived Cardiomyocytes and Simulations of Ik1 Ion Channels in Real-Time
in Cardiac Electrophysiology
Frontiers in Physiology
doi 10.3389/fphys.2017.01094
- 8,425 views
- 52 citations
Brief Research Report
Published on 26 Nov 2019
Usefulness of Bnet, a Simple Linear Metric in Discerning Torsades De Pointes Risks in 28 CiPA Drugs
in Cardiovascular and Smooth Muscle Pharmacology
Frontiers in Pharmacology
doi 10.3389/fphar.2019.01419
- 3,959 views
- 11 citations