Recombinant Factor Viii | List of Frontiers open access articles

Original Research

Published on 07 Feb 2020

Recombinant Factor VIII Fc Inhibits B Cell Activation via Engagement of the FcγRIIB Receptor

in Immunological Tolerance and Regulation

Maria T. Georgescu
Paul C. Moorehead
Tongyao Liu
Jennifer Dumont
David W. Scott
Christine Hough
David Lillicrap

Frontiers in Immunology

doi 10.3389/fimmu.2020.00138

6,284 views
9 citations

Review

Published on 03 Dec 2019

Status of Recombinant Factor VIII Concentrate Treatment for Hemophilia A in Italy: Characteristics and Clinical Benefits

in Hematology

Mario Schiavoni
Mariasanta Napolitano
Gaetano Giuffrida
Antonella Coluccia
Sergio Siragusa
Valeria Calafiore
Giuseppe Lassandro
Paola Giordano

Frontiers in Medicine

doi 10.3389/fmed.2019.00261

20,532 views
30 citations

Original Research

Published on 03 Nov 2022

Recombinant factor VIII Fc fusion protein engages monocytes via Fc and FVIII domains to reduce monocyte differentiation into osteoclasts

in Immunobiology and Immunotherapy

Susu Duan
Yifan Dang
Gaurav Manohar Rajani
Katalin Kis-Toth
Joe Salas

Frontiers in Hematology

doi 10.3389/frhem.2022.1020852

2,916 views
1 citation

Systematic Review

Published on 07 Oct 2025

Cost-effectiveness of emicizumab for the treatment of hemophilia A: a systematic review

in Health Economics

Min Chen
Yunzhu Lin
Guoqian He
Liang Huang
Junyi Han
Jiaqi Ni

Frontiers in Public Health

doi 10.3389/fpubh.2025.1658760

2,944 views
1 citation

Mini Review

Published on 04 Jun 2019

Immunomodulation in Primary Immune Thrombocytopenia: A Possible Role of the Fc Fragment of Romiplostim?

in Immunological Tolerance and Regulation

Alexandra Schifferli
Falk Nimmerjahn
Thomas Kühne

Frontiers in Immunology

doi 10.3389/fimmu.2019.01196

9,173 views
22 citations

Original Research

Published on 09 Apr 2024

Factor VIII moiety of recombinant Factor VIII Fc fusion protein impacts Fc effector function and CD16+ NK cell activation

in Immunological Tolerance and Regulation

H.A. Daniel Lagassé
Jiayi Ou
Zuben E. Sauna
Basil Golding

Frontiers in Immunology

doi 10.3389/fimmu.2024.1341013

3,751 views
1 citation

Case Report

Published on 18 Jul 2025

Progressive cephalohematoma in a neonate revealing severe hemophilia a owing to intron 22 inversion: a case report

in Pediatric Hematology and Hematological Malignancies

Cheng Peng
Qiuyue Kou
Qianqian Xia
Zhongfen Cao
Lili Liu
Xinlin Hou
Zezhong Tang

Frontiers in Pediatrics

doi 10.3389/fped.2025.1649183

2,589 views

Articles

Recombinant Factor VIII Fc Inhibits B Cell Activation via Engagement of the FcγRIIB Receptor

Status of Recombinant Factor VIII Concentrate Treatment for Hemophilia A in Italy: Characteristics and Clinical Benefits

Recombinant factor VIII Fc fusion protein engages monocytes via Fc and FVIII domains to reduce monocyte differentiation into osteoclasts

Cost-effectiveness of emicizumab for the treatment of hemophilia A: a systematic review

Immunomodulation in Primary Immune Thrombocytopenia: A Possible Role of the Fc Fragment of Romiplostim?

Factor VIII moiety of recombinant Factor VIII Fc fusion protein impacts Fc effector function and CD16+ NK cell activation

Progressive cephalohematoma in a neonate revealing severe hemophilia a owing to intron 22 inversion: a case report