Research Problems | List of Frontiers open access articles

Systematic Review

Published on 06 Mar 2026

Performance of artificial intelligence models designed as adjuncts for determining working length and apical landmark assessment in endodontic procedures: a systematic review

in Dental Materials

Sanjeev B. Khanagar
Majed Alharthi
Adel Asery
Muhammad Alalweet
Abdullah Aldobiyan
Meshal Alhayf
Ahmed Binobaid

Frontiers in Dental Medicine

doi 10.3389/fdmed.2026.1783828

Review

Published on 06 Mar 2026

Role of lactylation-induced macrophage failed phenotypic switching in sustaining inflammation of diabetic wounds

in Inflammation

Jiatong Wang
Kairui Wang
Zhihan Hu
Yunwei Wang
Yuchen Kang
Xiaohui Liu
Yuheng Zhang
Yi Liu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1777272

129 views

Mini Review

Published on 06 Mar 2026

Midline congenital upper lip sinus: a rare clinical case with analytical review of diagnostic and therapy strategies

in Pediatric Otolaryngology

Shuang Yang
Kai Kang
Wei Liu
Zhibo Zhou

Frontiers in Pediatrics

doi 10.3389/fped.2026.1777126

100 views

Original Research

Published on 06 Mar 2026

Clinical and immunological differentiation of isolated IgG and combined IgG & IgM deficiencies from common variable immunodeficiency

in Primary Immunodeficiencies

Yagmur Dogru
Faranaz Atschekzei
Damla Dogru
Torsten Witte
Georgios Sogkas

Frontiers in Immunology

doi 10.3389/fimmu.2026.1777332

148 views

Editorial

Published on 06 Mar 2026

Editorial: Safety and efficacy of CRISPR/Cas-based genome editing tools: applications and considerations in cell and gene therapy

in Cancer Immunity and Immunotherapy

Karl Petri
Samuele Ferrari
Beatrice Claudia Cianciotti

Frontiers in Immunology

doi 10.3389/fimmu.2026.1809809

Correction

Published on 06 Mar 2026

Correction: Neurodegeneration of the cornea and retina in patients with type 1 diabetes without clinical evidence of diabetic retinopathy

in Clinical Diabetes

Josie Carmichael
Hassan Fadavi
Mitra Tavakoli

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1809367

Original Research

Published on 06 Mar 2026

Genome-wide comparative analysis of the HSP90 gene family in four Ipomoea species and functional insights into the potentiality of IbHSP90–2 in low temperature tolerance

in Plant Abiotic Stress

Lizhe Shu
Kun Zhu
Xingyu Wang
Lilin Cheng
Shuo Zhou
Mingku Zhu
Xiaowan Gou
Zongyun Li

Frontiers in Plant Science

doi 10.3389/fpls.2026.1791008

239 views

Mini Review

Published on 06 Mar 2026

Bridging the translational gap in systems neuroscience: from circuit mechanisms to clinical therapeutics

in Neuropharmacology

Anyin Wang
Jiale Ye
Jie Li
Xiaoqin Chen
Qiaoyan Wang
Kunwei Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1791688

272 views

Original Research

Published on 06 Mar 2026

Generative AI–social media coordinated learning and university students' psychological well-being: dual pathways and the buffering role of perceived support

in Educational Psychology

Yu Chen
Guanxi Chen
Jiajun Chen

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1788850

182 views

Original Research

Published on 06 Mar 2026

Linking microbes to in situ methane oxidation rates in a eutrophic freshwater lake

in Aquatic Microbiology

Jennifer A. Baily
Zachary W. Hudspeth
Joshua L. Morningstar
Howard P. Mendlovitz
Christopher S. Martens
Karen G. Lloyd

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1789101

492 views

Case Report

Published on 06 Mar 2026

Case Report: Dual response to efgartigimod in myasthenia gravis and comorbid autoimmune disorders: a case series

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yunjia Li
Yingying Yang
Ying Zhu
Ruixia Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1788550

Original Research

Published on 06 Mar 2026

Systematic scale-up and enhanced purification of marine cyanophage P-SSP7

in Phage Biology

Pavlo Bohutskyi
Amar D. Parvate
Natalie C. Sadler
William B. Chrisler
Margaret S. Cheung
James E. Evans

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1776133

197 views

Original Research

Published on 06 Mar 2026

Interpretable AI for treatment decision-making in immunoradiotherapy of locally advanced nasopharyngeal carcinoma

in Pharmacology of Anti-Cancer Drugs

Guili Cao
Bin Zeng
Zifu Yuan
Xiao Hu
Hai Ou

Frontiers in Oncology

doi 10.3389/fonc.2026.1775802

127 views

Case Report

Published on 06 Mar 2026

Case report: Tumor-like mediastinal tuberculous lymphadenitis with paravertebral cold abscess under cumulative immunosuppression: a case highlighting altered host–pathogen interactions

in Microbial Immunology

Xiaoqing Zhou
Zhangjing Sun
Chen Chen
Xin Lv
Ruilin Chen
Zhen Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1780714

Systematic Review

Published on 06 Mar 2026

Prevalence of post-traumatic stress disorder in healthcare workers before and during COVID-19: a systematic review and meta-analysis

in Public Mental Health

Claire Frodsham
Samuel B. Harvey
Daniel Collins
Karen Krakue
Vita Ligaya Dalgaard
Rosie Lipscomb
Matthew Hotopf
Mark Deady
Richard Bryant
Aimee Gayed

Frontiers in Public Health

doi 10.3389/fpubh.2026.1735552

212 views

Original Research

Published on 06 Mar 2026

Pan-immune-inflammation value: racial variations and differences in prognostic accuracy across breast cancer subtypes at a single institution

in Breast Cancer

Indigo Johnson
Atif Bacchus
Ross Budziszewski
Scott D. Siegel
Jennifer Sims-Mourtada

Frontiers in Oncology

doi 10.3389/fonc.2026.1694711

156 views

Articles

Performance of artificial intelligence models designed as adjuncts for determining working length and apical landmark assessment in endodontic procedures: a systematic review

Role of lactylation-induced macrophage failed phenotypic switching in sustaining inflammation of diabetic wounds

Midline congenital upper lip sinus: a rare clinical case with analytical review of diagnostic and therapy strategies

Clinical and immunological differentiation of isolated IgG and combined IgG & IgM deficiencies from common variable immunodeficiency

Editorial: Safety and efficacy of CRISPR/Cas-based genome editing tools: applications and considerations in cell and gene therapy

Correction: Neurodegeneration of the cornea and retina in patients with type 1 diabetes without clinical evidence of diabetic retinopathy

Genome-wide comparative analysis of the HSP90 gene family in four Ipomoea species and functional insights into the potentiality of IbHSP90–2 in low temperature tolerance

Bridging the translational gap in systems neuroscience: from circuit mechanisms to clinical therapeutics

Generative AI–social media coordinated learning and university students' psychological well-being: dual pathways and the buffering role of perceived support

Linking microbes to in situ methane oxidation rates in a eutrophic freshwater lake

Case Report: Dual response to efgartigimod in myasthenia gravis and comorbid autoimmune disorders: a case series

Systematic scale-up and enhanced purification of marine cyanophage P-SSP7

Interpretable AI for treatment decision-making in immunoradiotherapy of locally advanced nasopharyngeal carcinoma

Case report: Tumor-like mediastinal tuberculous lymphadenitis with paravertebral cold abscess under cumulative immunosuppression: a case highlighting altered host–pathogen interactions

Prevalence of post-traumatic stress disorder in healthcare workers before and during COVID-19: a systematic review and meta-analysis

Pan-immune-inflammation value: racial variations and differences in prognostic accuracy across breast cancer subtypes at a single institution