Ropivacaine | List of Frontiers open access articles

Original Research

Published on 23 Feb 2022

Ropivacaine Inhibits Lung Cancer Cell Malignancy Through Downregulation of Cellular Signaling Including HIF-1α In Vitro

in Pharmacology of Anti-Cancer Drugs

Junmei Shen
Lina Han
Yongxian Xue
Chao Li
Huiqun Jia
Kangsheng Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.806954

3,003 views
13 citations

Original Research

Published on 11 Jan 2023

Effect of single spinal anesthesia with two doses ropivacaine on urinary retention after hemorrhoidectomy in male patients

in Genitourinary Surgery and Interventions

Lei-lei Wang
Meng Kang
Li-xin Duan
Xu-fei Chang
Xiao-xin Li
Xiang-yang Guo
Zhi-yu Kang
Yong-zheng Han

Frontiers in Surgery

doi 10.3389/fsurg.2022.1077575

5,851 views
4 citations

Original Research

Published on 18 Nov 2021

Circadian Variation in the Median Effective Dose of Epidural Ropivacaine for Labor Analgesia

in Intensive Care Medicine and Anesthesiology

Jiali Deng
Changna Wei
Lin Liu
Jing Qian
Fei Xiao
Xinzhong Chen

Frontiers in Medicine

doi 10.3389/fmed.2021.669264

2,748 views
3 citations

Clinical Trial

Published on 24 Jul 2024

The optimal dose of dexmedetomidine as a 0.59% ropivacaine adjuvant for epidural anesthesia in great saphenous varicose vein surgery, based on hemodynamics and anesthesia efficacy: a randomized, controlled, double-blind clinical trial

in Intensive Care Medicine and Anesthesiology

Sisi Zeng
Xuechao Li
Hongchun Xu
Qin Ye
Zhaogang Li
Fangjun Wang

Frontiers in Medicine

doi 10.3389/fmed.2024.1426512

3,100 views
2 citations

Clinical Trial

Published on 24 Jul 2025

ED50 and ED95 of hypobaric ropivacaine during unilateral spinal anesthesia in older patients undergoing hip replacement surgery

in Intensive Care Medicine and Anesthesiology

Chao Lin
Wen-Lin Xian
Jun Xu
Ting Zhao
Zhi-Qiang Wu
Fang-Jun Wang

Frontiers in Medicine

doi 10.3389/fmed.2025.1571574

1,784 views
2 citations

Clinical Trial

Published on 05 May 2023

ED90 of epidural esketamine with 0.075% ropivacaine for labor analgesia in nulliparous parturients: a prospective, randomized and dose-finding study

in Obstetric and Pediatric Pharmacology

Siwen Lou
Qiang Du
Liwei Yu
Qingfu Wang
Jing Yu
Zhong Mei

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1169415

3,121 views
11 citations

Clinical Trial

Published on 14 Jul 2025

Impact of temperature on EC50 of ropivacaine in axillary brachial plexus blocks: based on Dixon’s up-and-down method

in Intensive Care Medicine and Anesthesiology

Alin Wang
Yunhao Shao
Yuling Zheng
Xiaoling Li
Bixin Huang
Ying Mai
Zhongqi Zhang

Frontiers in Medicine

doi 10.3389/fmed.2025.1591581

1,835 views

Original Research

Published on 19 Jan 2023

Study on MEV90 of 0.5% ropivacaine for US-guided caudal epidural block in anorectal surgery

in Intensive Care Medicine and Anesthesiology

Pei Zhang
Hong Chang
Taoran Yang
Yalong Fu
Xuemei He
Jun Li
Mingan Yang
Rurong Wang
Xuehan Li

Frontiers in Medicine

doi 10.3389/fmed.2022.1077478

2,933 views
7 citations

Systematic Review

Published on 02 Oct 2024

A bibliometrics and visualization analysis of ropivacaine research from 2000 to 2023

in Intensive Care Medicine and Anesthesiology

Jian Zhang
Ye Liu
Xiyao Gu
Jing Chai

Frontiers in Medicine

doi 10.3389/fmed.2024.1465308

2,772 views
5 citations

Original Research

Published on 28 Apr 2025

Effect of dexmedetomidine on the median effective concentration of ropivacaine for postoperative analgesia in transversus abdominis plane block: an up-down sequential allocation study

in Intensive Care Medicine and Anesthesiology

Qin Ye
Hongchun Xu
Xiao Liu
Xujiao Wang
Fangjun Wang

Frontiers in Medicine

doi 10.3389/fmed.2025.1491849

1,989 views

Brief Research Report

Published on 04 May 2022

Serum Concentration of Ropivacaine After Repeated Administration to Several Parts of the Head During Awake Craniotomy: A Prospective Cohort Study

in Intensive Care Medicine and Anesthesiology

Takehito Sato
Takahiro Ando
Ichiko Asano
Atsushi Mori
Kazuya Motomura
Kimitoshi Nishiwaki

Frontiers in Medicine

doi 10.3389/fmed.2022.834334

4,255 views
1 citation

Original Research

Published on 07 Jan 2025

A randomized sequential allocation study on the optimum programmed intermittent epidural boluses interval time with different concentrations of ropivacaine combined with the dural puncture epidural technique for labor analgesia

in Obstetric and Pediatric Pharmacology

Jingjing Mao
Yi Chen
Linsen Sun
Xiaoxiao Xu
Kai Xu
Tingting Ren
Xiangsheng Xiong
Weibing Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1508514

1,765 views
3 citations

Original Research

Published on 07 Jan 2025

LC-MS/MS assisted pharmacokinetic and tissue distribution study of ropivacaine and 3-OH-ropivacaine on rats after plane block anesthesia

in Drug Metabolism and Transport

Mihaela Butiulca
Lenard Farczadi
Silvia Imre
Camil Eugen Vari
Laurian Vlase
Bogdan Cordos
Leonard Azamfirei
Alexandra Elena Lazar

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1494646

1,873 views
1 citation

Original Research

Published on 26 Mar 2025

Comparison of the pharmacokinetic variations of different concentrations of ropivacaine used for serratus anterior plane block in patients undergoing thoracoscopic lobectomy: a population pharmacokinetics analysis

in Drug Metabolism and Transport

Jing Ling
Caomei Xu
Lingkai Tang
Lan Qiu
Nan Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1540606

1,732 views
2 citations

Original Research

Published on 21 Jan 2022

The Median Effective Concentration (EC50) of Epidural Ropivacaine With Different Doses of Oxycodone During Limb Surgery in Elderly Patients

in Geriatric Medicine

Kai Xie
Yu-long Wang
Wen-bin Teng
Rui He
Yu-hong Li
Su-qin Huang

Frontiers in Medicine

doi 10.3389/fmed.2021.808850

2,852 views
5 citations

Original Research

Published on 09 May 2024

Enhancing patient comfort in varicose vein treatment through combined lidocaine and ropivacaine tumescent anesthesia

in Vascular Surgery

Yubo Li
Tan Li

Frontiers in Surgery

doi 10.3389/fsurg.2024.1359474

3,594 views
2 citations

Articles

Ropivacaine Inhibits Lung Cancer Cell Malignancy Through Downregulation of Cellular Signaling Including HIF-1α In Vitro

Effect of single spinal anesthesia with two doses ropivacaine on urinary retention after hemorrhoidectomy in male patients

Circadian Variation in the Median Effective Dose of Epidural Ropivacaine for Labor Analgesia

The optimal dose of dexmedetomidine as a 0.59% ropivacaine adjuvant for epidural anesthesia in great saphenous varicose vein surgery, based on hemodynamics and anesthesia efficacy: a randomized, controlled, double-blind clinical trial

ED50 and ED95 of hypobaric ropivacaine during unilateral spinal anesthesia in older patients undergoing hip replacement surgery

ED90 of epidural esketamine with 0.075% ropivacaine for labor analgesia in nulliparous parturients: a prospective, randomized and dose-finding study

Impact of temperature on EC50 of ropivacaine in axillary brachial plexus blocks: based on Dixon’s up-and-down method

Study on MEV90 of 0.5% ropivacaine for US-guided caudal epidural block in anorectal surgery

A bibliometrics and visualization analysis of ropivacaine research from 2000 to 2023

Effect of dexmedetomidine on the median effective concentration of ropivacaine for postoperative analgesia in transversus abdominis plane block: an up-down sequential allocation study

Serum Concentration of Ropivacaine After Repeated Administration to Several Parts of the Head During Awake Craniotomy: A Prospective Cohort Study

A randomized sequential allocation study on the optimum programmed intermittent epidural boluses interval time with different concentrations of ropivacaine combined with the dural puncture epidural technique for labor analgesia

LC-MS/MS assisted pharmacokinetic and tissue distribution study of ropivacaine and 3-OH-ropivacaine on rats after plane block anesthesia

Comparison of the pharmacokinetic variations of different concentrations of ropivacaine used for serratus anterior plane block in patients undergoing thoracoscopic lobectomy: a population pharmacokinetics analysis

The Median Effective Concentration (EC50) of Epidural Ropivacaine With Different Doses of Oxycodone During Limb Surgery in Elderly Patients

Enhancing patient comfort in varicose vein treatment through combined lidocaine and ropivacaine tumescent anesthesia