Sepsis Associated Encephalopathy Sae | List of Frontiers open access articles

Review

Published on 26 Jul 2022

Central role of microglia in sepsis-associated encephalopathy: From mechanism to therapy

in Multiple Sclerosis and Neuroimmunology

Xiaoqian Yan
Kaiying Yang
Qi Xiao
Rongyao Hou
Xudong Pan
Xiaoyan Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2022.929316

17,270 views
79 citations

Review

Published on 13 May 2025

The progress of the microbe-gut-brain axis in sepsis-associated encephalopathy

in Clinical Infectious Diseases

Chen He
Hui Shi
Zhijie Yu
Chunhan Ma
Zhiqiang Jiao
Jin Li
Fei Yang

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1587463

3,376 views

Mini Review

Published on 28 Mar 2023

Application background and mechanism of short-chain fatty acids in sepsis-associated encephalopathy

in Intestinal Microbiome

Qiulei Zhang
Chang Lu
Weixuan Fan
Jingxiao Zhang
Yongjie Yin

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2023.1137161

8,105 views
13 citations

Review

Published on 27 Nov 2020

Microglia: A Potential Therapeutic Target for Sepsis-Associated Encephalopathy and Sepsis-Associated Chronic Pain

in Inflammation Pharmacology

Yi Li
Lu Yin
Zhongmin Fan
Binxiao Su
Yu Chen
Yan Ma
Ya Zhong
Wugang Hou
Zongping Fang
Xijing Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2020.600421

9,617 views
46 citations

Review

Published on 25 May 2023

Application of magnetic resonance imaging-related techniques in the diagnosis of sepsis-associated encephalopathy: present status and prospect

in Brain Imaging Methods

Shuhui Wu
Yuxin Wang
Yaqin Song
Hongjie Hu
Liang Jing
Wei Zhu

Frontiers in Neuroscience

doi 10.3389/fnins.2023.1152630

4,241 views
2 citations

Review

Published on 08 Jul 2025

Gut microbiota and sepsis-associated encephalopathy: pathogenesis and precision therapies

in Gut-Brain Axis

Na Wei
Shiyu Dai
Wei Li
Jun Zhou
Ye Chen

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1596467

2,684 views

Brief Research Report

Published on 15 Nov 2021

Blocking HMGB1/RAGE Signaling by Berberine Alleviates A1 Astrocyte and Attenuates Sepsis-Associated Encephalopathy

in Neuropharmacology

Jian Shi
Huan Xu
María José Cavagnaro
Xingmei Li
Jia Fang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.760186

7,373 views
38 citations

Review

Published on 16 Mar 2023

A summary of the current diagnostic methods for, and exploration of the value of microRNAs as biomarkers in, sepsis-associated encephalopathy

in Translational Neuroscience

Zhang Yuechen
Xi Shaosong
Zhang Zhouxing
Gu Fuli
Hu Wei

Frontiers in Neuroscience

doi 10.3389/fnins.2023.1125888

4,491 views
9 citations

Original Research

Published on 04 Jan 2023

Prognostic role of serum ammonia in patients with sepsis-associated encephalopathy without hepatic failure

in Infectious Diseases: Epidemiology and Prevention

Lina Zhao
Shaowei Hou
Risu Na
Bin Liu
Zhiwei Wang
Yun Li
Keliang Xie

Frontiers in Public Health

doi 10.3389/fpubh.2022.1016931

5,487 views
4 citations

Mini Review

Published on 10 Jun 2025

Targeting synaptic plasticity to bridge translational gaps in sepsis-associated encephalopathy

in Neuroinflammation and Neuropathy

Koji Hoshino

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1616736

3,095 views

Original Research

Published on 01 Feb 2023

Mast cell activation mediates blood–brain barrier impairment and cognitive dysfunction in septic mice in a histamine-dependent pathway

in Inflammation

Jianhe Yue
Ying Tan
Renzheng Huan
Jin Guo
Sha Yang
Mei Deng
Yunbiao Xiong
Guoqiang Han
Lin Liu
Jian Liu

Frontiers in Immunology

doi 10.3389/fimmu.2023.1090288

9,367 views
22 citations

Review

Published on 16 Mar 2022

Insight Into Regulatory T Cells in Sepsis-Associated Encephalopathy

in Multiple Sclerosis and Neuroimmunology

Yu-lei Gao
Yan-cun Liu
Xiang Zhang
Song-tao Shou
Yan-fen Chai

Frontiers in Neurology

doi 10.3389/fneur.2022.830784

5,618 views
8 citations

Original Research

Published on 09 Aug 2022

Neuronal MD2 induces long-term mental impairments in septic mice by facilitating necroptosis and apoptosis

in Neuropharmacology

Zhongmin Fan
Hongwei Ma
Yi Li
You Wu
Jiajia Wang
Lize Xiong
Zongping Fang
Xijing Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.884821

5,434 views
11 citations

Original Research

Published on 09 Jan 2023

Malvidin alleviates mitochondrial dysfunction and ROS accumulation through activating AMPK-α/UCP2 axis, thereby resisting inflammation and apoptosis in SAE mice

in Neuropharmacology

Panpan Zhao
Xiaomin Li
Qiankun Yang
Yingzhi Lu
Guanglu Wang
Haitao Yang
Jingquan Dong
Honggang Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1038802

8,145 views
40 citations

Original Research

Published on 06 Sep 2022

Integrated transcriptomics and metabolomics analysis of the hippocampus reveals altered neuroinflammation, downregulated metabolism and synapse in sepsis-associated encephalopathy

in Neuropharmacology

Kejia Xu
Hui Li
Bing Zhang
Meini Le
Qiong Huang
Rao Fu
Giorgia Croppi
Gang Qian
Junjie Zhang
Guangming Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1004745

6,159 views
16 citations

Original Research

Published on 28 Jan 2021

The Neuroprotective Effect of Short Chain Fatty Acids Against Sepsis-Associated Encephalopathy in Mice

in Microbial Immunology

Jiaming Liu
Yangjie Jin
Yanglie Ye
Yahui Tang
Shanshan Dai
Mengfang Li
Guangju Zhao
Guangliang Hong
Zhong-Qiu Lu

Frontiers in Immunology

doi 10.3389/fimmu.2021.626894

9,104 views
54 citations

Articles

Central role of microglia in sepsis-associated encephalopathy: From mechanism to therapy

The progress of the microbe-gut-brain axis in sepsis-associated encephalopathy

Application background and mechanism of short-chain fatty acids in sepsis-associated encephalopathy

Microglia: A Potential Therapeutic Target for Sepsis-Associated Encephalopathy and Sepsis-Associated Chronic Pain

Application of magnetic resonance imaging-related techniques in the diagnosis of sepsis-associated encephalopathy: present status and prospect

Gut microbiota and sepsis-associated encephalopathy: pathogenesis and precision therapies

Blocking HMGB1/RAGE Signaling by Berberine Alleviates A1 Astrocyte and Attenuates Sepsis-Associated Encephalopathy

A summary of the current diagnostic methods for, and exploration of the value of microRNAs as biomarkers in, sepsis-associated encephalopathy

Prognostic role of serum ammonia in patients with sepsis-associated encephalopathy without hepatic failure

Targeting synaptic plasticity to bridge translational gaps in sepsis-associated encephalopathy

Mast cell activation mediates blood–brain barrier impairment and cognitive dysfunction in septic mice in a histamine-dependent pathway

Insight Into Regulatory T Cells in Sepsis-Associated Encephalopathy

Neuronal MD2 induces long-term mental impairments in septic mice by facilitating necroptosis and apoptosis

Malvidin alleviates mitochondrial dysfunction and ROS accumulation through activating AMPK-α/UCP2 axis, thereby resisting inflammation and apoptosis in SAE mice

Integrated transcriptomics and metabolomics analysis of the hippocampus reveals altered neuroinflammation, downregulated metabolism and synapse in sepsis-associated encephalopathy

The Neuroprotective Effect of Short Chain Fatty Acids Against Sepsis-Associated Encephalopathy in Mice