Simultaneous Optimization | List of Frontiers open access articles

Case Report

Published on 27 Feb 2026

A novel technique of spacer implantation and proton beam therapy for hilar cholangiocarcinoma: a case report

in Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers

Wencui Yang
Junetsu Mizoe
Xiaolong Wang

Frontiers in Oncology

doi 10.3389/fonc.2026.1747997

Original Research

Published on 27 Feb 2026

From mathematics and science to classroom management: an IRT validation of a teaching confidence scale in a sample of primary special education teachers

in Special Educational Needs

Stergiani Giaouri
Alexandros-Stamatios Antoniou
Garyfalia Charitaki
Anastasia Alevriadou
Georgia Andreou
Maria Charisi

Frontiers in Education

doi 10.3389/feduc.2026.1753929

Review

Published on 27 Feb 2026

Female reproductive capacity preservation: antioxidant strategies in combating ovarian aging and cryopreservation challenges

in Reproduction

Bing Xie
Kaiqi Zhang
Jiao Lin
Haiying Cheng
Xianghong Huang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1711016

328 views

Original Research

Published on 27 Feb 2026

Triptolide alleviates hyperosmotic stress-induced human corneal epithelial cell damage by inhibiting NLRP3 inflammasome-mediated pyroptosis via the TLR4/NF-κB pathway

in Ophthalmology

Ran Xia
Bei Zhan
Liming Tao

Frontiers in Medicine

doi 10.3389/fmed.2026.1753857

Perspective

Published on 27 Feb 2026

A pilot study of a novel portable mass spectrometer for rapid, simultaneous detection of multiple anesthetic drug concentrations

in Anesthesiology and Animal Pain Management

Xiaoyu Xie
Xiaoxiao Li
Wensheng Zhang

Frontiers in Veterinary Science

doi 10.3389/fvets.2026.1776326

115 views

Review

Published on 27 Feb 2026

Visualizing spinal tumors: a review of intraoperative contrast enhanced ultrasound during spinal tumor resections

in Neuro-Oncology and Neurosurgical Oncology

Kyle P. Stegmann
Brian Fabian Saway
Liz Iglesias
Parker Dhillon
Jackson Maradik
Stephen Kalhorn

Frontiers in Oncology

doi 10.3389/fonc.2026.1742835

Original Research

Published on 27 Feb 2026

Microtransplantation improves the outcome of older patients with newly diagnosed acute myeloid leukemia: a single-center study with long-term follow-up

in Hematologic Malignancies

Juan Liu
Xiao-mei Huang
Xiao-shuang Li
Yan-yan Zhu
Pan-pan Lv
Ya-kun Yang
Tian Tian
Wan-jun Sun

Frontiers in Oncology

doi 10.3389/fonc.2026.1736302

107 views

Original Research

Published on 27 Feb 2026

The clinical value of repeat ultrasound-guided fine-needle aspiration biopsy in the management of Bethesda Category III thyroid nodules

in Thyroid Endocrinology

Chong Chen
Qingfeng Fu
Rundong He
Yiming Guo
Shuai Zhang
Ping Sun
Le Zhou
Hui Sun

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1750620

Original Research

Published on 27 Feb 2026

Brusatol inhibits metastasis of triple-negative breast cancer through metabolic reprogramming

in Breast Cancer

Xuan Yu
Xueling Diao
Xiaokai Fan
Chuantao Wu
Siyuan Wang
Maoxuan Liu
Edwin Cheung
Liang Chen

Frontiers in Oncology

doi 10.3389/fonc.2026.1708878

Original Research

Published on 27 Feb 2026

Mind–body exercise and anxiety in middle-aged and older adults: a sequential mediation model of emotion regulation and sleep quality

in Aging and Public Health

Yafei Zheng
Hengzhen Liang
Xiujie Ma

Frontiers in Public Health

doi 10.3389/fpubh.2026.1763761

Systematic Review

Published on 27 Feb 2026

Research trends of mitochondrial dysfunction in hepatic fibrosis: a bibliometric analysis

in Mitochondrial Research

Xingtao Jin
Yanlu Ma
Yiqiang Tang
Fengjie Qiao
Tong Xiao
Yu Cui
Man Li
Yueqiu Gao

Frontiers in Physiology

doi 10.3389/fphys.2026.1767822

131 views

Original Research

Published on 27 Feb 2026

Adverse childhood experiences, loneliness, and doomscrolling on social media newsfeeds among adult men across Generations X, Y, Z

in Gender, Sex and Sexualities

Sabina Lissitsa
Maya Kagan

Frontiers in Sociology

doi 10.3389/fsoc.2026.1700210

116 views

Original Research

Published on 27 Feb 2026

Spatiotemporal deep learning framework for predictive behavioral threat detection in surveillance footage

in Cybersecurity and Privacy

Asha Aruna Sheela Matta
Venkata Purna Chandra Sekhara Rao Manukonda

Frontiers in Big Data

doi 10.3389/fdata.2026.1770989

225 views

Brief Research Report

Published on 27 Feb 2026

Allelic diversity of the pharmacogenes CYP2D6 and CYP2C19 in Māori from Te Tairāwhiti, Aotearoa New Zealand

in Pharmacogenetics and Pharmacogenomics

Leonie Hitchman
Te Whetu Aarahi Kerekere
Allison L. Miller
Elizabeth Goodin
Caroline Koia
Huti Watson
Frances King
Stephen P. Robertson
Phillip Wilcox
Martin A. Kennedy

Frontiers in Genetics

doi 10.3389/fgene.2026.1668409

Brief Research Report

Published on 27 Feb 2026

Functional validation of the novel KIF5A p.R17Q VUS reveals defective axonal transport in iPSC-motoneurons from a SPG10 patient

in Stem Cell Research

Serena Santangelo
Valeria Casiraghi
Claudia Fallini
Sabrina Invernizzi
Silvia Peverelli
Martina Bertocchi
Monica Feole
Marta Cozzi
Stefania Magri
Angelo Poletti

Frontiers in Genetics

doi 10.3389/fgene.2026.1774170

Mini Review

Published on 27 Feb 2026

MRD in multiple myeloma: the clinical perspective

in Hematologic Malignancies

Tommaso Caravita di Toritto
Angela Rago

Frontiers in Oncology

doi 10.3389/fonc.2025.1740112

1,002 views

Articles

A novel technique of spacer implantation and proton beam therapy for hilar cholangiocarcinoma: a case report

From mathematics and science to classroom management: an IRT validation of a teaching confidence scale in a sample of primary special education teachers

Female reproductive capacity preservation: antioxidant strategies in combating ovarian aging and cryopreservation challenges

Triptolide alleviates hyperosmotic stress-induced human corneal epithelial cell damage by inhibiting NLRP3 inflammasome-mediated pyroptosis via the TLR4/NF-κB pathway

A pilot study of a novel portable mass spectrometer for rapid, simultaneous detection of multiple anesthetic drug concentrations

Visualizing spinal tumors: a review of intraoperative contrast enhanced ultrasound during spinal tumor resections

Microtransplantation improves the outcome of older patients with newly diagnosed acute myeloid leukemia: a single-center study with long-term follow-up

The clinical value of repeat ultrasound-guided fine-needle aspiration biopsy in the management of Bethesda Category III thyroid nodules

Brusatol inhibits metastasis of triple-negative breast cancer through metabolic reprogramming

Mind–body exercise and anxiety in middle-aged and older adults: a sequential mediation model of emotion regulation and sleep quality

Research trends of mitochondrial dysfunction in hepatic fibrosis: a bibliometric analysis

Adverse childhood experiences, loneliness, and doomscrolling on social media newsfeeds among adult men across Generations X, Y, Z

Spatiotemporal deep learning framework for predictive behavioral threat detection in surveillance footage

Allelic diversity of the pharmacogenes CYP2D6 and CYP2C19 in Māori from Te Tairāwhiti, Aotearoa New Zealand

Functional validation of the novel KIF5A p.R17Q VUS reveals defective axonal transport in iPSC-motoneurons from a SPG10 patient

MRD in multiple myeloma: the clinical perspective