Smad Pathway | List of Frontiers open access articles

Original Research

Accepted on 04 Feb 2026

Silencing MALAT1 represses pathological progression, inflammation, and vascular smooth muscle cell phenotype switching by regulating the SEMA3C-mediated Smad pathway in intracranial aneurysms

in Cellular Neuropathology

Junlong Kang
Wei Li
Xinjie Gao
Xinhua Tian
Wei Feng
Xiang Yao
Feng Wei
Luyue Chen
Hongjin Chen
Junjiang Tong

Frontiers in Cellular Neuroscience

125 views

Original Research

Published on 25 Sep 2018

Magnesium Isoglycyrrhizinate Ameliorates Fibrosis and Disrupts TGF-β-Mediated SMAD Pathway in Activated Hepatic Stellate Cell Line LX2

in Ethnopharmacology

Jie Kai Tee
Fei Peng
Yeong Lan Tan
Bo Yu
Han Kiat Ho

Frontiers in Pharmacology

doi 10.3389/fphar.2018.01018

9,268 views
27 citations

Review

Published on 06 Jun 2025

Mechanism of action and potential therapeutic targets of TGF-β-related signaling pathway and its downstream miRNA expression in pulmonary arterial hypertension

in Cardiovascular and Smooth Muscle Pharmacology

Yimo Huang
Wende Ma
Cen Guo
Xiaoling Su

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1596767

4,365 views
2 citations

Review

Published on 11 Mar 2025

Crosstalk of TGF-β and somatostatin signaling in adenocarcinoma and neuroendocrine tumors of the pancreas: a brief review

in Cancer Endocrinology

Hendrik Ungefroren
Harpal Randeva
Hendrik Lehnert
Jörg Schrader
Jens-Uwe Marquardt
Björn Konukiewitz
Ralf Hass

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1511348

3,414 views
2 citations

Original Research

Published on 26 Jun 2023

Transforming growth factor-β1 and SMAD signalling pathway in the small airways of smokers and patients with COPD: potential role in driving fibrotic type-2 epithelial mesenchymal transition

in Molecular Innate Immunity

Samuel James Brake
Wenying Lu
Collin Chia
Greg Haug
Josie Larby
Ashutosh Hardikar
Gurpreet K. Singhera
Tillie L. Hackett
Mathew Suji Eapen
Sukhwinder Singh Sohal

Frontiers in Immunology

doi 10.3389/fimmu.2023.1216506

5,896 views
18 citations

Original Research

Published on 01 Oct 2021

Saikosaponin D Inhibits Peritoneal Fibrosis in Rats With Renal Failure by Regulation of TGFβ1/ BMP7 / Gremlin1/ Smad Pathway

in Renal Pharmacology

Liu Ruiqi
Pei Ming
Su Qihang
Lei Yangyang
Chen Junli
Lin Wei
Gao Chao
Liu Xinyue
Yang Kang
Yang Hongtao

Frontiers in Pharmacology

doi 10.3389/fphar.2021.628671

4,903 views
12 citations

Original Research

Published on 23 Jul 2019

(Pro)renin Receptor-Dependent Induction of Profibrotic Factors Is Mediated by COX-2/EP4/NOX-4/Smad Pathway in Collecting Duct Cells

in Translational Pharmacology

Cristian Reyes-Martinez
Quynh My Nguyen
Modar Kassan
Alexis A. Gonzalez

Frontiers in Pharmacology

doi 10.3389/fphar.2019.00803

4,309 views
15 citations

Articles

Silencing MALAT1 represses pathological progression, inflammation, and vascular smooth muscle cell phenotype switching by regulating the SEMA3C-mediated Smad pathway in intracranial aneurysms

Magnesium Isoglycyrrhizinate Ameliorates Fibrosis and Disrupts TGF-β-Mediated SMAD Pathway in Activated Hepatic Stellate Cell Line LX2

Mechanism of action and potential therapeutic targets of TGF-β-related signaling pathway and its downstream miRNA expression in pulmonary arterial hypertension

Crosstalk of TGF-β and somatostatin signaling in adenocarcinoma and neuroendocrine tumors of the pancreas: a brief review

Transforming growth factor-β1 and SMAD signalling pathway in the small airways of smokers and patients with COPD: potential role in driving fibrotic type-2 epithelial mesenchymal transition

Saikosaponin D Inhibits Peritoneal Fibrosis in Rats With Renal Failure by Regulation of TGFβ1/ BMP7 / Gremlin1/ Smad Pathway

(Pro)renin Receptor-Dependent Induction of Profibrotic Factors Is Mediated by COX-2/EP4/NOX-4/Smad Pathway in Collecting Duct Cells