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5 articles related to "Smoothened Receptor"

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Articles

Original Research

Published on 04 Jun 2019

Deciphering the Allosteric Effect of Antagonist Vismodegib on Smoothened Receptor Deactivation Using Metadynamics Simulation

in Medicinal and Pharmaceutical Chemistry

Xiaoli An
Qifeng Bai
Fang Bai
Danfeng Shi
Huanxiang Liu
Xiaojun Yao

Frontiers in Chemistry

doi 10.3389/fchem.2019.00406

4,217 views
2 citations

Mini Review

Published on 10 Dec 2021

Contribution of Smoothened Receptor Signaling in GABAergic Neurotransmission and Chloride Homeostasis in the Developing Rodent Brain

in Membrane Physiology and Membrane Biophysics

Mira Hamze
Igor Medina
Quentin Delmotte
Christophe Porcher

Frontiers in Physiology

doi 10.3389/fphys.2021.798066

3,902 views
5 citations

Original Research

Published on 15 Oct 2024

Pharmacological targeting of smoothened receptor cysteine-rich domain by Budesonide promotes in vitro myelination

in Methods and Model Organisms

Antonella Damiana Recchia
Alessandra Dominicis
Vincenzo Maria D'Amore
Tommaso Fabiano
Aland Ibrahim Ahmed Al Jaf
Simone Peria
Francesco Basoli
Alberto Rainer
Luciana Marinelli
Francesco Saverio Di Leva

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1473960

4,697 views
1 citation

Original Research

Published on 18 Jan 2017

Neuroprotective Effects of a Smoothened Receptor Agonist against Early Brain Injury after Experimental Subarachnoid Hemorrhage in Rats

in Non-Neuronal Cells

Quan Hu
Tong Li
Lingxiao Wang
Yunkai Xie
Song Liu
Xuemei Bai
Tiantian Zhang
Shishi Bo
Danqing Xin
Hao Xue

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2016.00306

6,272 views
28 citations

Original Research

Published on 21 Feb 2019

L-4, a Well-Tolerated and Orally Active Inhibitor of Hedgehog Pathway, Exhibited Potent Anti-tumor Effects Against Medulloblastoma in vitro and in vivo

in Pharmacology of Anti-Cancer Drugs

Mingfei Zhu
Hong Wang
Chenglin Wang
Yanfen Fang
Tong Zhu
Weili Zhao
Xiaochun Dong
Xiongwen Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2019.00089

4,725 views
11 citations