Sorafenib Sensitivity | List of Frontiers open access articles

Original Research

Published on 07 Dec 2021

SENP2 Reduces Hepatocellular Carcinoma Stemness and Improves Sorafenib Sensitivity Through Inactivating the AKT/GSK3β/CTNNB1 Pathway

in Molecular and Cellular Oncology

Xiaohui Tang
Bohao Liu
Chen Zhang
Wenbin Tang
Shitian Liang
Yadan Xiao
Ruoyu Deng
Zhuan Li

Frontiers in Oncology

doi 10.3389/fonc.2021.773045

4,796 views
10 citations

Original Research

Published on 18 May 2021

Development of an Aerobic Glycolysis Index for Predicting the Sorafenib Sensitivity and Prognosis of Hepatocellular Carcinoma

in Gastrointestinal Cancers

Yu Pan
Geng-yuan Hu
Shi Jiang
Shun-jie Xia
Hendi Maher
Zhong-jie Lin
Qi-jiang Mao
Jie Zhao
Liu-xin Cai
Ying-hua Xu

Frontiers in Oncology

doi 10.3389/fonc.2021.637971

4,426 views
4 citations

Original Research

Published on 11 Mar 2022

Knockdown of AKR1C3 Promoted Sorafenib Sensitivity Through Inhibiting the Phosphorylation of AKT in Hepatocellular Carcinoma

in Pharmacology of Anti-Cancer Drugs

Jia Zheng
Zhihong Yang
Yanlei Li
Li Yang
Ruili Yao

Frontiers in Oncology

doi 10.3389/fonc.2022.823491

7,253 views
14 citations

Original Research

Published on 21 Jan 2021

Metformin Resensitizes Sorafenib-Resistant HCC Cells Through AMPK-Dependent Autophagy Activation

in Molecular and Cellular Oncology

Hong-Yue Lai
Hsin-Hwa Tsai
Chia-Jui Yen
Liang-Yi Hung
Ching-Chieh Yang
Chung-Han Ho
Hsin-Yin Liang
Feng-Wei Chen
Chien-Feng Li
Ju-Ming Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2020.596655

9,268 views
41 citations

Original Research

Published on 15 May 2025

Study on the mechanism by which Xuanfu Hua Tang increases sensitivity of hepatocellular carcinoma cells to sorafenib by antagonizing the Notch1 pathway through HIF-2α

in Molecular and Cellular Oncology

Wenzhao Luo
Xian Li
Yiwan Shang
Zhen Chen
Yinglin Cui

Frontiers in Oncology

doi 10.3389/fonc.2025.1552480

1,884 views

Original Research

Published on 16 Feb 2026

RPL28 mediates sorafenib resistance in hepatocellular carcinoma by downregulating CDC6 expression

in Cancer Molecular Targets and Therapeutics

Yi Shi
Fangfang Chen
Yuanyuan Weng
Hang Zeng
Gang Chen

Frontiers in Oncology

doi 10.3389/fonc.2026.1741406

387 views

Review

Published on 08 Jun 2016

Modulation of Autophagy by Sorafenib: Effects on Treatment Response

in Cancer Molecular Targets and Therapeutics

Nestor Prieto-Domínguez
Raquel Ordóñez
Anna Fernández
Andres García-Palomo
Jordi Muntané
Javier González-Gallego
José L. Mauriz

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00151

15,764 views
112 citations

Articles

SENP2 Reduces Hepatocellular Carcinoma Stemness and Improves Sorafenib Sensitivity Through Inactivating the AKT/GSK3β/CTNNB1 Pathway

Development of an Aerobic Glycolysis Index for Predicting the Sorafenib Sensitivity and Prognosis of Hepatocellular Carcinoma

Knockdown of AKR1C3 Promoted Sorafenib Sensitivity Through Inhibiting the Phosphorylation of AKT in Hepatocellular Carcinoma

Metformin Resensitizes Sorafenib-Resistant HCC Cells Through AMPK-Dependent Autophagy Activation

Study on the mechanism by which Xuanfu Hua Tang increases sensitivity of hepatocellular carcinoma cells to sorafenib by antagonizing the Notch1 pathway through HIF-2α

RPL28 mediates sorafenib resistance in hepatocellular carcinoma by downregulating CDC6 expression

Modulation of Autophagy by Sorafenib: Effects on Treatment Response