Tissue Growth Factor | List of Frontiers open access articles

Original Research

Published on 05 Feb 2024

The association of plasma connective tissue growth factor levels with left ventricular diastolic dysfunction in patients with overt hyperthyroidism

in Thyroid Endocrinology

Huan Li
Yahui Ren
Linfang Wang
Yuming Li

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1333001

1,866 views

Original Research

Published on 21 Jan 2022

Kinsenoside Protects Against Radiation-Induced Liver Fibrosis via Downregulating Connective Tissue Growth Factor Through TGF-β1 Signaling

in Gastrointestinal and Hepatic Pharmacology

Xiaoqi Nie
Qianqian Yu
Long Li
Minxiao Yi
Bili Wu
Yongbiao Huang
Yonghui Zhang
Hu Han
Xianglin Yuan

Frontiers in Pharmacology

doi 10.3389/fphar.2022.808576

4,983 views
15 citations

Original Research

Published on 20 Feb 2019

Genetic Elimination of Connective Tissue Growth Factor in the Forebrain Affects Subplate Neurons in the Cortex and Oligodendrocytes in the Underlying White Matter

I-Shing Yu
Ho-Ching Chang
Ko-Chien Chen
Yi-Ling Lu
Horng-Tzer Shy
Chwen-Yu Chen
Kuang-Yung Lee
Li-Jen Lee

Frontiers in Neuroanatomy

doi 10.3389/fnana.2019.00016

7,634 views
17 citations

Original Research

Published on 25 May 2021

Connective Tissue Growth Factor Is Overexpressed in Explant Lung Tissue and Broncho-Alveolar Lavage in Transplant-Related Pulmonary Fibrosis

in Alloimmunity and Transplantation

Arno Vanstapel
Roel Goldschmeding
Roel Broekhuizen
Tri Nguyen
Annelore Sacreas
Janne Kaes
Tobias Heigl
Stijn E. Verleden
Alexandra De Zutter
Geert Verleden

Frontiers in Immunology

doi 10.3389/fimmu.2021.661761

5,944 views
15 citations

Original Research

Published on 14 Sep 2021

Connective Tissue Growth Factor From Periosteal Tartrate Acid Phosphatase-Positive Monocytes Direct Skeletal Stem Cell Renewal and Fate During Bone Healing

in Cellular Biochemistry

Yun Bai
Tao Yu
Jiezhong Deng
Yusheng Yang
Jiulin Tan
Qijie Dai
Zehua Zhang
Shiwu Dong
Jianzhong Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.730095

6,449 views
1 citation

Original Research

Published on 09 Dec 2020

Cyclic Stretch Induces Vascular Smooth Muscle Cells to Secrete Connective Tissue Growth Factor and Promote Endothelial Progenitor Cell Differentiation and Angiogenesis

in Cell Adhesion and Migration

Jing Yan
Wen-Bin Wang
Yang-Jing Fan
Han Bao
Na Li
Qing-Ping Yao
Yun-Long Huo
Zong-Lai Jiang
Ying-Xin Qi
Yue Han

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2020.606989

10,101 views
19 citations

Original Research

Published on 08 Aug 2018

Rapamycin Upregulates Connective Tissue Growth Factor Expression in Hepatic Progenitor Cells Through TGF-β-Smad2 Dependent Signaling

in Gastrointestinal and Hepatic Pharmacology

Yu Wu
Wei Wang
Xiang-mei Peng
Yi He
Yi-xiao Xiong
Hui-fang Liang
Liang Chu
Bi-xiang Zhang
Ze-yang Ding
Xiao-ping Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2018.00877

7,227 views
25 citations

Original Research

Published on 27 Feb 2018

Vascular Endothelial Cell-Specific Connective Tissue Growth Factor (CTGF) Is Necessary for Development of Chronic Hypoxia-Induced Pulmonary Hypertension

in Respiratory Physiology and Pathophysiology

Liya Pi
Chunhua Fu
Yuanquing Lu
Junmei Zhou
Marda Jorgensen
Vinayak Shenoy
Kenneth E. Lipson
Edward W. Scott
Andrew J. Bryant

Frontiers in Physiology

doi 10.3389/fphys.2018.00138

8,432 views
31 citations

Review

Published on 29 Oct 2020

Connective Tissue Growth Factor: From Molecular Understandings to Drug Discovery

in Cellular Biochemistry

Zihao Chen
Ning Zhang
Hang Yin Chu
Yuanyuan Yu
Zong-Kang Zhang
Ge Zhang
Bao-Ting Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2020.593269

38,015 views
129 citations

Original Research

Published on 21 Aug 2025

Locked nucleic acid-modified antisense oligonucleotides attenuate scar hyperplasia through targeted inhibition of CTGF

in Translational Pharmacology

Jinhe Li
Xi Wu
Ying Yang
Ruiqi Mao
Zherui Li
Xiujun Zhang
Wenguo Wei
Wendi Wang
Hailong Li
Honggang Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1623640

2,454 views

Original Research

Published on 29 Nov 2021

PDGF Promotes Dermal Fibroblast Activation via a Novel Mechanism Mediated by Signaling Through MCHR1

in Autoimmune and Autoinflammatory Disorders

Naoko Takamura
Ludivine Renaud
Willian Abraham da Silveira
Carol Feghali-Bostwick

Frontiers in Immunology

doi 10.3389/fimmu.2021.745308

10,671 views
20 citations

Original Research

Published on 05 Aug 2022

Connective tissue growth factor-targeting DNA aptamer suppresses pannus formation as diagnostics and therapeutics for rheumatoid arthritis

in Autoimmune and Autoinflammatory Disorders

Gan Wu
Can Liu
Ben Cao
Zelin Cao
Haige Zhai
Bin Liu
Shengwei Jin
Xinyu Yang
Chen Lv
Jianguang Wang

Frontiers in Immunology

doi 10.3389/fimmu.2022.934061

5,638 views
10 citations

Brief Research Report

Published on 17 Feb 2021

P2Y1 Receptor Agonist Attenuates Cardiac Fibroblasts Activation Triggered by TGF-β1

in Experimental Pharmacology and Drug Discovery

Geer Tian
Junteng Zhou
Yue Quan
Qihang Kong
Wenchao Wu
Xiaojing Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.627773

4,861 views
14 citations

Original Research

Published on 03 Nov 2022

Substrate stiffness engineered to replicate disease conditions influence senescence and fibrotic responses in primary lung fibroblasts

in Respiratory Pharmacology

Kaj E. C. Blokland
Mehmet Nizamoglu
Habibie Habibie
Theo Borghuis
Michael Schuliga
Barbro N. Melgert
Darryl A. Knight
Corry-Anke Brandsma
Simon D. Pouwels
Janette K. Burgess

Frontiers in Pharmacology

doi 10.3389/fphar.2022.989169

9,917 views
37 citations

Original Research

Published on 11 Oct 2021

Transforming Growth Factor Beta 1 Alters Glucose Uptake but Not Insulin Signalling in Human Primary Myotubes From Women With and Without Polycystic Ovary Syndrome

in Obesity

Luke C. McIlvenna
Rhiannon K. Patten
Andrew J. McAinch
Raymond J. Rodgers
Nigel K. Stepto
Alba Moreno-Asso

Frontiers in Endocrinology

doi 10.3389/fendo.2021.732338

4,882 views
16 citations

Review

Published on 22 Apr 2022

Aging of the Peritoneal Dialysis Membrane

in Renal Physiology and Pathophysiology

Raymond T. Krediet

Frontiers in Physiology

doi 10.3389/fphys.2022.885802

9,477 views
15 citations

Articles

The association of plasma connective tissue growth factor levels with left ventricular diastolic dysfunction in patients with overt hyperthyroidism

Kinsenoside Protects Against Radiation-Induced Liver Fibrosis via Downregulating Connective Tissue Growth Factor Through TGF-β1 Signaling

Genetic Elimination of Connective Tissue Growth Factor in the Forebrain Affects Subplate Neurons in the Cortex and Oligodendrocytes in the Underlying White Matter

Connective Tissue Growth Factor Is Overexpressed in Explant Lung Tissue and Broncho-Alveolar Lavage in Transplant-Related Pulmonary Fibrosis

Connective Tissue Growth Factor From Periosteal Tartrate Acid Phosphatase-Positive Monocytes Direct Skeletal Stem Cell Renewal and Fate During Bone Healing

Cyclic Stretch Induces Vascular Smooth Muscle Cells to Secrete Connective Tissue Growth Factor and Promote Endothelial Progenitor Cell Differentiation and Angiogenesis

Rapamycin Upregulates Connective Tissue Growth Factor Expression in Hepatic Progenitor Cells Through TGF-β-Smad2 Dependent Signaling

Vascular Endothelial Cell-Specific Connective Tissue Growth Factor (CTGF) Is Necessary for Development of Chronic Hypoxia-Induced Pulmonary Hypertension

Connective Tissue Growth Factor: From Molecular Understandings to Drug Discovery

Locked nucleic acid-modified antisense oligonucleotides attenuate scar hyperplasia through targeted inhibition of CTGF

PDGF Promotes Dermal Fibroblast Activation via a Novel Mechanism Mediated by Signaling Through MCHR1

Connective tissue growth factor-targeting DNA aptamer suppresses pannus formation as diagnostics and therapeutics for rheumatoid arthritis

P2Y1 Receptor Agonist Attenuates Cardiac Fibroblasts Activation Triggered by TGF-β1

Substrate stiffness engineered to replicate disease conditions influence senescence and fibrotic responses in primary lung fibroblasts

Transforming Growth Factor Beta 1 Alters Glucose Uptake but Not Insulin Signalling in Human Primary Myotubes From Women With and Without Polycystic Ovary Syndrome

Aging of the Peritoneal Dialysis Membrane