Triazole Derivatives | List of Frontiers open access articles

Original Research

Published on 17 Nov 2022

Study of the anticancer effect of new quinazolinone hydrazine derivatives as receptor tyrosine kinase inhibitors

in Medicinal and Pharmaceutical Chemistry

Motahareh Mortazavi
Masoumeh Divar
Tahereh Damghani
Fatemeh Moosavi
Luciano Saso
Somayeh Pirhadi
Mehdi Khoshneviszadeh
Najmeh Edraki
Omidreza Firuzi

Frontiers in Chemistry

doi 10.3389/fchem.2022.969559

10,172 views
25 citations

Original Research

Published on 23 Oct 2024

Synthesis of new triazole derivatives and their potential applications for removal of heavy metals from aqueous solution and antibacterial activities

in Medicinal and Pharmaceutical Chemistry

Chunyun Xu
Na Yang
Haichun Yu
Xiaojing Wang

Frontiers in Chemistry

doi 10.3389/fchem.2024.1473097

4,310 views
2 citations

Review

Published on 20 May 2021

Triazole-Modified Peptidomimetics: An Opportunity for Drug Discovery and Development

in Medicinal and Pharmaceutical Chemistry

Agnieszka Staśkiewicz
Patrycja Ledwoń
Paolo Rovero
Anna Maria Papini
Rafal Latajka

Frontiers in Chemistry

doi 10.3389/fchem.2021.674705

13,002 views
37 citations

Original Research

Published on 26 Feb 2025

Discovery of triazole derivatives for biofilm disruption, anti-inflammation and metal ion chelation

in Medicinal and Pharmaceutical Chemistry

Shuang Hong
Hongzhi Lu
Dawei Tian
Yue Chang
Qi Lu
Feng Gao

Frontiers in Chemistry

doi 10.3389/fchem.2025.1545259

4,196 views
5 citations

Original Research

Published on 06 Mar 2025

Design and evaluation of novel triazole derivatives as potential anti-gout inhibitors: a comprehensive molecular modeling study

in Theoretical and Computational Chemistry

Mohammed Er-rajy
Mohamed El fadili
Sara Zarougui
Somdutt Mujwar
Mourad Aloui
Mohammed Zerrouk
Belkheir Hammouti
Larbi Rhazi
Rachid Sabbahi
Mohammed M. Alanazi

Frontiers in Chemistry

doi 10.3389/fchem.2025.1518777

8,843 views
16 citations

Original Research

Published on 30 Jun 2021

Synthesis of New 1H-1,2,3-Triazole Analogs in Aqueous Medium via “Click” Chemistry: A Novel Class of Potential Carbonic Anhydrase-II Inhibitors

in Organic Chemistry

Satya Kumar Avula
Majid Khan
Sobia Ahsan Halim
Ajmal Khan
Samia Ahmed Al-Riyami
Rene Csuk
Biswanath Das
Ahmed Al-Harrasi

Frontiers in Chemistry

doi 10.3389/fchem.2021.642614

16,234 views
18 citations

Original Research

Published on 11 Dec 2020

Mono-Alkylated Ligands Based on Pyrazole and Triazole Derivatives Tested Against Fusarium oxysporum f. sp. albedinis: Synthesis, Characterization, DFT, and Phytase Binding Site Identification Using Blind Docking/Virtual Screening for Potent Fophy Inhibitors

in Medicinal and Pharmaceutical Chemistry

Yassine Kaddouri
Farid Abrigach
Sabir Ouahhoud
Redouane Benabbes
Mohamed El Kodadi
Ali Alsalme
Nabil Al-Zaqri
Ismail Warad
Rachid Touzani

Frontiers in Chemistry

doi 10.3389/fchem.2020.559262

12,012 views
15 citations

Original Research

Published on 05 Apr 2024

Exploring theophylline-1,2,4-triazole tethered N-phenylacetamide derivatives as antimicrobial agents: unraveling mechanisms via structure-activity relationship, in vitro validation, and in silico insights

in Medicinal and Pharmaceutical Chemistry

Sadaf Saeed
Irum Shahzadi
Ameer Fawad Zahoor
Aamal A. Al-Mutairi
Shagufta Kamal
Shah Faisal
Ali Irfan
Sami A. Al-Hussain
Muhammed Tilahun Muhammed
Magdi E. A. Zaki

Frontiers in Chemistry

doi 10.3389/fchem.2024.1372378

9,020 views
4 citations

Original Research

Published on 21 Dec 2020

Interleukin-1 Receptor Modulation Using β-Substituted α-Amino-γ-Lactam Peptides From Solid-Phase Synthesis and Diversification

in Medicinal and Pharmaceutical Chemistry

Azade Geranurimi
Colin W. H. Cheng
Christiane Quiniou
France Côté
Xin Hou
Isabelle Lahaie
Amarilys Boudreault
Sylvain Chemtob
William D. Lubell

Frontiers in Chemistry

doi 10.3389/fchem.2020.610431

4,770 views
6 citations

Articles

Study of the anticancer effect of new quinazolinone hydrazine derivatives as receptor tyrosine kinase inhibitors

Synthesis of new triazole derivatives and their potential applications for removal of heavy metals from aqueous solution and antibacterial activities

Triazole-Modified Peptidomimetics: An Opportunity for Drug Discovery and Development

Discovery of triazole derivatives for biofilm disruption, anti-inflammation and metal ion chelation

Design and evaluation of novel triazole derivatives as potential anti-gout inhibitors: a comprehensive molecular modeling study

Synthesis of New 1H-1,2,3-Triazole Analogs in Aqueous Medium via “Click” Chemistry: A Novel Class of Potential Carbonic Anhydrase-II Inhibitors

Mono-Alkylated Ligands Based on Pyrazole and Triazole Derivatives Tested Against Fusarium oxysporum f. sp. albedinis: Synthesis, Characterization, DFT, and Phytase Binding Site Identification Using Blind Docking/Virtual Screening for Potent Fophy Inhibitors

Exploring theophylline-1,2,4-triazole tethered N-phenylacetamide derivatives as antimicrobial agents: unraveling mechanisms via structure-activity relationship, in vitro validation, and in silico insights

Interleukin-1 Receptor Modulation Using β-Substituted α-Amino-γ-Lactam Peptides From Solid-Phase Synthesis and Diversification