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3 articles related to "Ultralong Cdr3"

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Articles

Original Research

Published on 25 Oct 2021

Milking the Cow: Cattle-Derived Chimeric Ultralong CDR-H3 Antibodies and Their Engineered CDR-H3-Only Knobbody Counterparts Targeting Epidermal Growth Factor Receptor Elicit Potent NK Cell-Mediated Cytotoxicity

in Vaccines and Molecular Therapeutics

Lukas Pekar
Daniel Klewinghaus
Paul Arras
Stefania C. Carrara
Julia Harwardt
Simon Krah
Desislava Yanakieva
Lars Toleikis
Vaughn V. Smider
Harald Kolmar

Frontiers in Immunology

doi 10.3389/fimmu.2021.742418

9,106 views
20 citations

Perspective

Published on 04 Jun 2018

Diversity in the Cow Ultralong CDR H3 Antibody Repertoire

in B Cell Biology

Jeremy K. Haakenson
Ruiqi Huang
Vaughn V. Smider

Frontiers in Immunology

doi 10.3389/fimmu.2018.01262

12,777 views
41 citations

Original Research

Published on 24 Oct 2023

Cattle-derived knob paratopes grafted onto peripheral loops of the IgG1 Fc region enable the generation of a novel symmetric bispecific antibody format

in Cancer Immunity and Immunotherapy

Desislava Yanakieva
Lena Vollmer
Andreas Evers
Vanessa Siegmund
Paul Arras
Lukas Pekar
Achim Doerner
Bernhard Valldorf
Harald Kolmar
Stefan Zielonka

Frontiers in Immunology

doi 10.3389/fimmu.2023.1238313

6,514 views
7 citations