Validation Design | List of Frontiers open access articles

Original Research

Published on 06 Mar 2026

Development and efficacy evaluation of a competency-based training program for pediatric operating room nurses

in Healthcare Professions Education

Qingqing Du
Zhen Wang
Mengfan Xia
Jing Cao
Yingmin Liu
Ziwei Jin
Xia Yang

Frontiers in Medicine

doi 10.3389/fmed.2026.1769565

Original Research

Published on 06 Mar 2026

Selinexor enhances the sensitivity of hepatocellular carcinoma cells to sorafenib by regulating the BAX/Bcl-2/PUMA apoptotic pathway and the XPO1/p27 cell cycle pathway

in Cancer Molecular Targets and Therapeutics

Shenghong Du
Ling Wang
Chen Chen
Yu Sun
Qian Liu
Jingfei Shi
Feng Zhang
Kai Wang
Chao Cui

Frontiers in Oncology

doi 10.3389/fonc.2026.1762822

Original Research

Published on 06 Mar 2026

Evaluation of FGL1 as a hepatokine marker in iron deficiency

in Clinical Nutrition

Muhammad Saboor
Raghad Abdul Rahim
Shamsah Nabi Dad
Abeer Mohamed Yusuf
Mshael Mohammed Nasser
Hayat Mohsen Mansoor
Adnane Guella
Noura Alkhayyal

Frontiers in Nutrition

doi 10.3389/fnut.2026.1767385

106 views

Original Research

Published on 06 Mar 2026

Development and validation of a predictive model for cognitive impairment after first-episode acute ischemic stroke without reperfusion therapy

in Neuroepidemiology

Jiangnan Li
Yufan Pu
Yaran Li
Xuejing Li

Frontiers in Neurology

doi 10.3389/fneur.2026.1731060

Original Research

Published on 06 Mar 2026

Amyloid-β acute exposition affects the CA1 hippocampal network activity and its topological organization, evaluated with multielectrode arrays

in Cellular and Molecular Mechanisms of Dementia

David Alcantara-Gonzalez
Elizabeth Santiago
Fernando Peña-Ortega

Frontiers in Dementia

doi 10.3389/frdem.2026.1738954

146 views

Original Research

Published on 06 Mar 2026

Dual effects of slightly acidic electrolyzed water on rice seed germination: insights from water dynamics via low-field NMR

in Crop and Product Physiology

Tiangang Hou
Fangming Cui
Mengnan Yang
Wenzhong Zhang
Jiping Gao
Mingjin Xin
Hongguang Cui
Cuihong Liu
Liyan Wu

Frontiers in Plant Science

doi 10.3389/fpls.2026.1740753

Review

Published on 06 Mar 2026

Role of lactylation-induced macrophage failed phenotypic switching in sustaining inflammation of diabetic wounds

in Inflammation

Jiatong Wang
Kairui Wang
Zhihan Hu
Yunwei Wang
Yuchen Kang
Xiaohui Liu
Yuheng Zhang
Yi Liu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1777272

Original Research

Published on 06 Mar 2026

Navigating language learning through metalinguistic beliefs: a theoretical exploration informed by multilingual narratives

in Bilingualism

Constanza Quinteros Ortiz

Frontiers in Language Sciences

doi 10.3389/flang.2026.1757671

102 views

Original Research

Published on 06 Mar 2026

Pan-immune-inflammation value: racial variations and differences in prognostic accuracy across breast cancer subtypes at a single institution

in Breast Cancer

Indigo Johnson
Atif Bacchus
Ross Budziszewski
Scott D. Siegel
Jennifer Sims-Mourtada

Frontiers in Oncology

doi 10.3389/fonc.2026.1694711

Original Research

Published on 06 Mar 2026

Acute effect of citrulline malate on flow-mediated dilation and serum pharmacodynamics in healthy young males

in Vascular Physiology

Johan Grannes
Nigel A. Callender
Adam M. Gonzalez
Jonny Hisdal
Fredrik T. Vårvik
Thomas Bjørnsen

Frontiers in Physiology

doi 10.3389/fphys.2026.1773582

229 views

Mini Review

Published on 06 Mar 2026

Endonasal flap reconstruction in sinonasal malignancy

in Head and Neck Cancer

Kalpesh Hathi
Christopher J. Chin

Frontiers in Oncology

doi 10.3389/fonc.2026.1777655

Original Research

Published on 06 Mar 2026

Interpretable AI for treatment decision-making in immunoradiotherapy of locally advanced nasopharyngeal carcinoma

in Pharmacology of Anti-Cancer Drugs

Guili Cao
Bin Zeng
Zifu Yuan
Xiao Hu
Hai Ou

Frontiers in Oncology

doi 10.3389/fonc.2026.1775802

Original Research

Published on 06 Mar 2026

Genome-wide identification of the HSF gene family in Chinese chestnut and functional characterization of CmHSF4 under temperature stress

in Plant Abiotic Stress

XiuRong Xu
ZiQi Wu
Xibing Jiang
Shiming Cheng

Frontiers in Plant Science

doi 10.3389/fpls.2026.1749489

184 views

Original Research

Published on 06 Mar 2026

Effect of building representation on pluvial flood risk in urban areas: the Podoniftis basin, Greece

in Urban Science

Marcos Julien Alexopoulos
Panayiotis Dimitriadis
Emela Mitsi
Demetris Koutsoyiannis
Denis Istrati
Theano Iliopoulou

Frontiers in Built Environment

doi 10.3389/fbuil.2026.1757749

174 views

Original Research

Published on 06 Mar 2026

Sperm whale hotspots off western Ireland and the importance of dynamic variables as shown by a multiscale Bayesian additive regression trees workflow

in Marine Megafauna

Cynthia Barile
Simon Berrow
Jonathan Gordon
Rossa Meade
Morgane Pommier
Joanne O’Brien

Frontiers in Marine Science

doi 10.3389/fmars.2026.1767540

149 views

Case Report

Published on 06 Mar 2026

Next generation sequencing guided treatment of ALK tyrosine kinase inhibitor induced long survival in lung squamous cell carcinoma harboring ROS1 gene fusions: a case report and literature review

in Precision Medicine

Mei Liu
Fenge Li
Ning Mu
Ning Kang
Shengnan Wu
Yue Xu
Xinyi Wang
Huan Lü
Chunhua Ma

Frontiers in Medicine

doi 10.3389/fmed.2026.1771353

Articles

Development and efficacy evaluation of a competency-based training program for pediatric operating room nurses

Selinexor enhances the sensitivity of hepatocellular carcinoma cells to sorafenib by regulating the BAX/Bcl-2/PUMA apoptotic pathway and the XPO1/p27 cell cycle pathway

Evaluation of FGL1 as a hepatokine marker in iron deficiency

Development and validation of a predictive model for cognitive impairment after first-episode acute ischemic stroke without reperfusion therapy

Amyloid-β acute exposition affects the CA1 hippocampal network activity and its topological organization, evaluated with multielectrode arrays

Dual effects of slightly acidic electrolyzed water on rice seed germination: insights from water dynamics via low-field NMR

Role of lactylation-induced macrophage failed phenotypic switching in sustaining inflammation of diabetic wounds

Navigating language learning through metalinguistic beliefs: a theoretical exploration informed by multilingual narratives

Pan-immune-inflammation value: racial variations and differences in prognostic accuracy across breast cancer subtypes at a single institution

Acute effect of citrulline malate on flow-mediated dilation and serum pharmacodynamics in healthy young males

Endonasal flap reconstruction in sinonasal malignancy

Interpretable AI for treatment decision-making in immunoradiotherapy of locally advanced nasopharyngeal carcinoma

Genome-wide identification of the HSF gene family in Chinese chestnut and functional characterization of CmHSF4 under temperature stress

Effect of building representation on pluvial flood risk in urban areas: the Podoniftis basin, Greece

Sperm whale hotspots off western Ireland and the importance of dynamic variables as shown by a multiscale Bayesian additive regression trees workflow

Next generation sequencing guided treatment of ALK tyrosine kinase inhibitor induced long survival in lung squamous cell carcinoma harboring ROS1 gene fusions: a case report and literature review