Immunology Research Topics

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Immunology Research Topics

Frontiers’ Research Topics are open, collaborative article collections built around emerging themes — connecting researchers to publish, discuss, and discover together.

Defined and led by expert researchers, they bring together communities to write, review, and publish articles around a shared interest – sparking conversation, stimulating collaboration, and accelerating scientific discovery. These collections showcase high-quality research, helping you boost visibility, impact, and citations.

Frontiers in Immunology is the official journal of the International Union of Immunological Societies (IUIS) and the most cited in its field, leading the way for research across basic, translational and clinical immunology.

Research Topics

Explore open Research Topics in Immunology below and submit yours today.

Doctor examined the patient's ear with Otoscope. Patient seem to have problems with hearing.

Exploring Immunological Factors in Inner Ear Disorders: Allergy and Inflammation

This Research Topic aims to dissect the intricate interplay between allergic responses and inflammation in the development and exacerbation of inner ear disorders. The goal is to enhance our understanding of immunological mechanisms at work, which could...

T-lymphocytes and dendritic cells, 3D-rendering;
Dendritic cells are antigen-presenting cells of the immune system. They process antigen material and present it on the cell surface to the T-cells.

Immuno-Metabolic Regulation of Antigen Presentation

This Research Topic aims to deepen our understanding of the way metabolic pathways influence immune responses through antigen presentation. The main objective is to unravel the mechanisms by which metabolic changes impact APC functionality.

Antibodies attacking neuron, 3D illustration. Concept of autoimmune neurologic diseases; Shutterstock ID 1776491966; purchase_order: Bynder Library; job: ; client: ; other:

Host-Microbiota Interactions in Autoimmunity and Inflammatory Diseases: Exploring Therapeutic Opportunities

This Research Topic aims to enhance our understanding of the interactions between the host and microbiota and their role in regulating the immune system and contributing to immune dysfunction. We invite both basic and translational studies that explore...

Lupus erythematosus cells (LE cells) on 100X light microscop stain.

Biologics and Targeted Therapies for Autoimmune and Auto-inflammatory Dermatoses: Balancing Efficacy with Safety and Toxicity

This Research Topic will focus on recent advancements in the treatment of autoimmune and auto-inflammatory skin diseases using biologic agents, targeted therapies, and cell-based approaches. Authors are encouraged to contribute original...

Bryonia, stem with sieve plates - microscopic cross section cut of a plant stem - dark field

Immune Challenges and Innovations in Lipid-Encapsulated Biotherapeutics

This research topic aims to explore and publish high-quality reviews and original research articles that delve into the immune response to lipid-encapsulated biotherapeutics. The objective is to position the Special Issue of Frontiers in Immunology...

Skin cancer cells, 3D illustration

Advances in the Understanding of the Immune System Relationship with Neoplasia and Immuno-oncology Approaches

This Research Topic welcomes manuscripts that deal with all aspects of the immune response in hematological neoplasia and cancer, from basic to clinical research and integrative analyses (including mice models and artificial intelligence analyses).

Meat breed of red pigs Duroc. Boars grazing outdoors in a dirty farm field. Red Hogging swine. Concept growing organic food. Big hog

Immunology of Farm Animals in the Context of One Health

One Health emphasizes the interconnectedness of human, animal, and environmental health, with immunology playing a pivotal role in understanding immune responses across these domains. Immune responses in animals and humans are intricately linked to...

Translational Research on Cancer Immunity and Immunotherapy: Preclinical and Clinical Investigations from Latin America

This Research Topic aims to provide an overview of current research on the field of cancer immunotherapy, with particular focus on their translation into the development of new cancer immunotherapeutic agents and combinations.

Real photo of stem cells

Antiseptic Potential of Tissue Stem Cell Secretomes in Regenerative Medicine

This Research Topic investigates the regenerative potential of adult stem cell secretomes, focusing on their composition of growth factors, cytokines, and extracellular vesicles that mediate tissue repair and regeneration in a cell-free manner.

Antibodies ( Immunoglobulin ) are small proteins that are part of the immune system's response to infection. Antibodies neutralize or destroy bacteria and viruses, 3d illustration

Treating Immune Dysregulation in Inborn Errors of Immunity: from conventional strategies to targeted therapies

This Research Topic aims to collect scientific studies about the multiple aspects of the therapeutic approaches of IEIs based on their causative molecular defects, helping to contribute to define optimal clinical management of IEIs in the evolution of...

Lymphocytes cell in the immune system reacting and attacking a spreading cancer cell - 3d illustration

Immunomodulation of the Immune System by Phytochemicals: Exploring the Therapeutic Potential of Natural Compounds

This Research Topic examines the immunomodulatory potential of natural compounds and phytochemicals in promoting balanced immune responses and supporting overall health. Highlighting their diverse roles in enhancing pathogen defense, regulating...

Doctor examined the patient's ear with Otoscope. Patient seem to have problems with hearing.

Exploring Immunological Factors in Inner Ear Disorders: Allergy and Inflammation

This Research Topic aims to dissect the intricate interplay between allergic responses and inflammation in the development and exacerbation of inner ear disorders. The goal is to enhance our understanding of immunological mechanisms at work, which could...

T-lymphocytes and dendritic cells, 3D-rendering;
Dendritic cells are antigen-presenting cells of the immune system. They process antigen material and present it on the cell surface to the T-cells.

Immuno-Metabolic Regulation of Antigen Presentation

This Research Topic aims to deepen our understanding of the way metabolic pathways influence immune responses through antigen presentation. The main objective is to unravel the mechanisms by which metabolic changes impact APC functionality.

Antibodies attacking neuron, 3D illustration. Concept of autoimmune neurologic diseases; Shutterstock ID 1776491966; purchase_order: Bynder Library; job: ; client: ; other:

Host-Microbiota Interactions in Autoimmunity and Inflammatory Diseases: Exploring Therapeutic Opportunities

This Research Topic aims to enhance our understanding of the interactions between the host and microbiota and their role in regulating the immune system and contributing to immune dysfunction. We invite both basic and translational studies that explore...

Lupus erythematosus cells (LE cells) on 100X light microscop stain.

Biologics and Targeted Therapies for Autoimmune and Auto-inflammatory Dermatoses: Balancing Efficacy with Safety and Toxicity

This Research Topic will focus on recent advancements in the treatment of autoimmune and auto-inflammatory skin diseases using biologic agents, targeted therapies, and cell-based approaches. Authors are encouraged to contribute original...

Bryonia, stem with sieve plates - microscopic cross section cut of a plant stem - dark field

Immune Challenges and Innovations in Lipid-Encapsulated Biotherapeutics

This research topic aims to explore and publish high-quality reviews and original research articles that delve into the immune response to lipid-encapsulated biotherapeutics. The objective is to position the Special Issue of Frontiers in Immunology...

Skin cancer cells, 3D illustration

Advances in the Understanding of the Immune System Relationship with Neoplasia and Immuno-oncology Approaches

This Research Topic welcomes manuscripts that deal with all aspects of the immune response in hematological neoplasia and cancer, from basic to clinical research and integrative analyses (including mice models and artificial intelligence analyses).

Meat breed of red pigs Duroc. Boars grazing outdoors in a dirty farm field. Red Hogging swine. Concept growing organic food. Big hog

Immunology of Farm Animals in the Context of One Health

One Health emphasizes the interconnectedness of human, animal, and environmental health, with immunology playing a pivotal role in understanding immune responses across these domains. Immune responses in animals and humans are intricately linked to...

Translational Research on Cancer Immunity and Immunotherapy: Preclinical and Clinical Investigations from Latin America

This Research Topic aims to provide an overview of current research on the field of cancer immunotherapy, with particular focus on their translation into the development of new cancer immunotherapeutic agents and combinations.

Real photo of stem cells

Antiseptic Potential of Tissue Stem Cell Secretomes in Regenerative Medicine

This Research Topic investigates the regenerative potential of adult stem cell secretomes, focusing on their composition of growth factors, cytokines, and extracellular vesicles that mediate tissue repair and regeneration in a cell-free manner.

Antibodies ( Immunoglobulin ) are small proteins that are part of the immune system's response to infection. Antibodies neutralize or destroy bacteria and viruses, 3d illustration

Treating Immune Dysregulation in Inborn Errors of Immunity: from conventional strategies to targeted therapies

This Research Topic aims to collect scientific studies about the multiple aspects of the therapeutic approaches of IEIs based on their causative molecular defects, helping to contribute to define optimal clinical management of IEIs in the evolution of...

Lymphocytes cell in the immune system reacting and attacking a spreading cancer cell - 3d illustration

Immunomodulation of the Immune System by Phytochemicals: Exploring the Therapeutic Potential of Natural Compounds

This Research Topic examines the immunomodulatory potential of natural compounds and phytochemicals in promoting balanced immune responses and supporting overall health. Highlighting their diverse roles in enhancing pathogen defense, regulating...

What are the benefits of Research Topics?

Whatever stage you're at in your career, participating in a Research Topic is a valuable experience. Whether you're looking for new connections, new opportunities, or a way to make a lasting difference in your field, there are many reasons to get involved.

How can publishing in Research Topics help you?

Publishing in a Research Topic can:

increase your article’s visibility
position your work within a themed collection alongside other experts
expand your professional network
open doors for future projects and collaborations.