Toxicology

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Toxicology is the study of the adverse effects of substances on living organisms. Our Research Topics encompass environmental, clinical, and forensic toxicology, focusing on the detection, mechanisms, and impact of toxins. By advancing our understanding of chemical hazards, biological responses, and new approach methodologies, we strive to enhance public health and environmental protection while addressing the effects and impact of toxic exposures.

The following Research Topics are led by experts in their field and contribute to the scientific understanding of toxicology. These Research topics are published in the peer-reviewed journal Frontiers in Toxicology, as open access articles.

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Research Topics

Frontiers' Research Topics are peer-reviewed article collections around cutting-edge research themes.
Learn more about how Research topics work.

Female athlete doing physical effort on stepper and doctor with tablet in hand pursues her. Sports tests

Advancing Sports Cardiology: New Frontiers in Athlete Screening and Recovery

Sports cardiology is an evolving field at the intersection of athletic performance and cardiovascular health. As technologies advance and athlete demographics diversify

Microplastics inside the soil. Concept of global warming and climate change. Non-recyclable plastic pollution in the soil at the field.s

Unravelling micro-/nano-plastics toxicity profiling: can we link associated effects to intrinsic characteristics?

This research topic aims to deliver the latest scientific developments and findings on the toxicology of micro- and nanoplastics exposures with specific focus on new test-methods and approaches that allow for a sensitive and in-depth effect assessment.

Confocal microscopy image of human neurons from the ventral midbrain region.

The need to add whole organism models to reduce uncertainties in developmental neurotoxicity testing strategies.

The goal of this Research Topic is to address the added value of whole organism models for DNT related testing strategies and IATAs and how these models can be an addition to the existing cell-based assays to better predict developmental neurotoxicity.

close up of empty used plastic bottles on white background with clipping path

Unraveling the Impact of Plasticizers on Human Health: Insights from Gut Microbiota and Toxicological Perspectives

This Research Topic aims to investigate the intricate effects of plasticizers on human health and disease. Specifically, we seek to explore their mechanisms of action, toxicokinetics, and potential contributions to various health conditions.

closeup of woman smoking e-cigarette and enjoying smoke. Copy space

Application of New Approach Methodologies in Toxicological Assessment of Next Generation Tobacco and Nicotine Products

The aim of this Research Topic is to showcase NAM-based toxicological risk assessment for next generation tobacco and nicotine products (NGPs) for the purpose of product screening/testing and pre-market regulatory submission.

Male workers on the field stack lettuce in boxes

Climate Change Impact on Workplace Health and Toxicological Risks

This Research Topic aims to explore the intricate link between climate change and occupational health, with a primary focus on the rising toxicological risks in diverse work environments.

Scientist or Biologist check waste water train from industrial, Toxic water pollution from industrial

New methods and approaches in toxicology of emerging environmental contaminants

This Research Topic aims to showcase the latest research in this field and highlight new tools and strategies to better understand the toxicity of emerging environmental pollutants.

Synapse and Neuron cells sending electrical chemical signals (3D illustration)

Impact of environmental chemicals on the brain: Models, Mechanisms, and Therapeutic Strategies

This Research Topic aims to address the significance and impact of environmental contaminants on the brain and related neurological disorders.

Medical concept in the field of nanotechnology. Genetic engineering and the use of nanorobots to replace part of the DNA molecule. 3 D illustration.

Exploring Novel Drug Delivery Approaches: Balancing Therapeutic Efficacy and Assessing Risks of Toxicity

This Research Topic aims to present the most recent scientific advancements and findings related to nanotechnology in drug delivery, with a focus on balancing therapeutic efficacy and the risk of toxicity.

Algal bloom in water of Dnieper river in Ukraine. Green color of water caused by a rapid increase or accumulation of algae. Ecological disaster. Water pollution. Natural green abstract background

Methods and approaches in the detection and removal of Cyanotoxins

This Research Topic focuses on advanced cyanotoxin detection and removal methods, including specialized extraction structures, on-site detection sensors, and innovative materials and devices for precise and accessible monitoring.

3d rendering of Human cell or Embryonic stem cell microscope background.

From North to South: A Global Perspective on the Impact of Endocrine Disruptors on Reproductive Development and Function

The goal of this Research Topic is to highlight EDC research related to reproductive toxicity in parts of the world where fewer studies are typically published.

Female athlete doing physical effort on stepper and doctor with tablet in hand pursues her. Sports tests

Advancing Sports Cardiology: New Frontiers in Athlete Screening and Recovery

Sports cardiology is an evolving field at the intersection of athletic performance and cardiovascular health. As technologies advance and athlete demographics diversify

Microplastics inside the soil. Concept of global warming and climate change. Non-recyclable plastic pollution in the soil at the field.s

Unravelling micro-/nano-plastics toxicity profiling: can we link associated effects to intrinsic characteristics?

This research topic aims to deliver the latest scientific developments and findings on the toxicology of micro- and nanoplastics exposures with specific focus on new test-methods and approaches that allow for a sensitive and in-depth effect assessment.

Confocal microscopy image of human neurons from the ventral midbrain region.

The need to add whole organism models to reduce uncertainties in developmental neurotoxicity testing strategies.

The goal of this Research Topic is to address the added value of whole organism models for DNT related testing strategies and IATAs and how these models can be an addition to the existing cell-based assays to better predict developmental neurotoxicity.

close up of empty used plastic bottles on white background with clipping path

Unraveling the Impact of Plasticizers on Human Health: Insights from Gut Microbiota and Toxicological Perspectives

This Research Topic aims to investigate the intricate effects of plasticizers on human health and disease. Specifically, we seek to explore their mechanisms of action, toxicokinetics, and potential contributions to various health conditions.

closeup of woman smoking e-cigarette and enjoying smoke. Copy space

Application of New Approach Methodologies in Toxicological Assessment of Next Generation Tobacco and Nicotine Products

The aim of this Research Topic is to showcase NAM-based toxicological risk assessment for next generation tobacco and nicotine products (NGPs) for the purpose of product screening/testing and pre-market regulatory submission.

Male workers on the field stack lettuce in boxes

Climate Change Impact on Workplace Health and Toxicological Risks

This Research Topic aims to explore the intricate link between climate change and occupational health, with a primary focus on the rising toxicological risks in diverse work environments.

Scientist or Biologist check waste water train from industrial, Toxic water pollution from industrial

New methods and approaches in toxicology of emerging environmental contaminants

This Research Topic aims to showcase the latest research in this field and highlight new tools and strategies to better understand the toxicity of emerging environmental pollutants.

Synapse and Neuron cells sending electrical chemical signals (3D illustration)

Impact of environmental chemicals on the brain: Models, Mechanisms, and Therapeutic Strategies

This Research Topic aims to address the significance and impact of environmental contaminants on the brain and related neurological disorders.

Medical concept in the field of nanotechnology. Genetic engineering and the use of nanorobots to replace part of the DNA molecule. 3 D illustration.

Exploring Novel Drug Delivery Approaches: Balancing Therapeutic Efficacy and Assessing Risks of Toxicity

This Research Topic aims to present the most recent scientific advancements and findings related to nanotechnology in drug delivery, with a focus on balancing therapeutic efficacy and the risk of toxicity.

Algal bloom in water of Dnieper river in Ukraine. Green color of water caused by a rapid increase or accumulation of algae. Ecological disaster. Water pollution. Natural green abstract background

Methods and approaches in the detection and removal of Cyanotoxins

This Research Topic focuses on advanced cyanotoxin detection and removal methods, including specialized extraction structures, on-site detection sensors, and innovative materials and devices for precise and accessible monitoring.

3d rendering of Human cell or Embryonic stem cell microscope background.

From North to South: A Global Perspective on the Impact of Endocrine Disruptors on Reproductive Development and Function

The goal of this Research Topic is to highlight EDC research related to reproductive toxicity in parts of the world where fewer studies are typically published.