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Original Research ARTICLE Provisionally accepted The full-text will be published soon. Notify me

Front. Med. | doi: 10.3389/fmed.2019.00190

Sleep characteristics and influencing factors of sleep quality in patients with inflammatory bowel disease arthritis

Yin Zhang1, Bin Pi2, Xianlin Xu1, Ying Li3, Xiangfan Chen3,  Ningxi Yang3* and Xiaoyan Li3
  • 1Department of Gastroenterology, Huiyang Sanhe Hospital, China
  • 2Fifth Affiliated Hospital, Department of Orthopedics, Guangzhou Medical University, China
  • 3School of Health Science, Wuhan University, China

Background: Patients with inflammatory bowel disease arthritis(IBDA)often accompany by sleep problems, but few studies have used polysomnography to investigate the objective sleep characteristics of IBDA.
Methods: Patients in IBDA group, inflammatory bowel disease (IBD) group, healthy control (HC) group were examined by polysomnography (PSG) and the sleep characteristics were compared. Then the influencing factors of sleep efficiency in IBDA patients were analyzed.
Results:There were significant differences in sleep parameters among the three groups (P<0.0001). The total sleep time (TST), rapid-eye-movement sleep (REM)time, slow wave sleep (S3 + S4) and sleep efficiency (SE) in the IBDA group were significantly less than those in the HC group and IBD group (P < 0.05), while the number and time of wake after sleep onset (WASO) and sleep latency (SL) were significantly longer than those in the HC group and IBD group (P < 0.05). For the above indicators, there was significant difference between patients in IBD group and HC group (P < 0.05). Hormone use, nocturnal gastrointestinal symptoms, joint pain, depression and disease in active phase were the influencing factors of sleep efficiency in patients with IBDA.
Conclusions: The sleep quality of patients with IBD was poor than the control group, and that of patients with IBDA was even worse. Therefore, sleep management should be included in IBD management.

Keywords: inflammatory bowel disease, Arthritis, Sleep disturbances, Polysomnography, Pittsburgh Sleep Quality Scale (PSQI)

Received: 14 Apr 2019; Accepted: 09 Aug 2019.

Copyright: © 2019 Zhang, Pi, Xu, Li, Chen, Yang and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Mx. Ningxi Yang, Wuhan University, School of Health Science, Wuhan, 430072, Hubei Province, China, yangningxi@bjmu.edu.cn