BRIEF RESEARCH REPORT article
Front. Arachn. Sci.
Sec. Arachnid Toxinology and Biochemistry
Unusual Paralytic Response to Amblyomma maculatum Nymphal Bite in Alpha-Gal knockout Mice
Provisionally accepted
- School of Biological, Environmental and Earth Sciences, University of Southern Mississippi, Hattiesburg, United States
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The Gulf-Coast tick (Amblyomma maculatum) is an emerging species whose geographic range is expanding in the United States. Although tick bite-induced paralysis is uncommon, Am. maculatum has been implicated in cases affecting vertebrate hosts. We report a rare case of paralysis in α-Gal-deficient mice following nymphal tick attachment. Notably, the symptoms resolved rapidly after the nymph was removed.
Keywords: Ticks, Amblyomma maculatum, Paralysis, Alpha-gal syndrome, Mice
Received: 20 Sep 2025; Accepted: 24 Nov 2025.
Copyright: © 2025 Oyediran and Karim. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Shahid Karim
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