BRIEF RESEARCH REPORT article
Front. Neural Circuits
Volume 19 - 2025 | doi: 10.3389/fncir.2025.1646317
This article is part of the Research TopicBridging Computation, Biophysics, Medicine, and Engineering in Neural CircuitsView all 12 articles
Spike-timing-dependent plasticity offers delay-gated oscillatory potentiation for autaptic weights
Provisionally accepted
- 1Faculty of Science and Engineering, Waseda University, Tokyo, Japan
- 2Tohoku Daigaku, Sendai, Japan
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Neuronal networks in animal brains are considered to realize specific filter functions through the precise configuration of synaptic weights, which are autonomously regulated without external supervision. In this study, we employ a single Hodgkin-Huxley-type neuron with autapses as a minimum model to computationally investigate how spike-timing-dependent plasticity (STDP) adjusts synaptic weights through recurrent feedback. The results show that the weights undergo oscillatory potentiation or depression with respect to autaptic delay and high-frequency stimulation. Our findings suggest that the STDP-mediated modulation of autaptic weights, governed by autaptic delay and input frequency, may serve as a mechanism for promoting network-level synchronization in neural systems if the network contains neurons with autapses.
Keywords: Autapse, spontaneous firing, STDP, recurrent connection, selection rule
Received: 13 Jun 2025; Accepted: 28 Jul 2025.
Copyright: © 2025 Onda, Ishida, Hattori, Yamamoto and TANII. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Takashi TANII, Faculty of Science and Engineering, Waseda University, Tokyo, Japan
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