MINI REVIEW article
Oncol. Rev.
Sec. Oncology Reviews: Reviews
Volume 19 - 2025 | doi: 10.3389/or.2025.1607983
This article is part of the Research TopicAutophagy in Solid Tumors and Inflammation: Mechanisms and TherapiesView all articles
Mitophagy in the Mechanisms of Treatment Resistance in Solid Tumors
Provisionally accepted
- Weifang People's Hospital, Weifang, China
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This review aims to explore the mechanisms by which mitophagy contributes to treatment resistance in solid tumors. As advancements in cancer therapies continue to evolve, treatment resistance emerges as a significant barrier to successful tumor management. Mitophagy, a specific form of cellular autophagy, has been implicated in the survival, proliferation, and drug resistance of tumor cells. This article will summarize the latest research findings and analyze how mitophagy impacts the biological characteristics of solid tumors, thereby revealing its potential implications in cancer treatment strategies. By understanding the role of mitophagy in the context of treatment resistance, we may uncover new therapeutic targets and strategies to enhance the efficacy of existing cancer treatments.
Keywords: mitophagy, solid tumors, treatment resistance, Cellular autophagy, Tumor biology
Received: 08 Apr 2025; Accepted: 11 Jul 2025.
Copyright: © 2025 Yan, Hui, Ren and Zang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Lei Zang, Weifang People's Hospital, Weifang, China
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