BRIEF RESEARCH REPORT article
Front. Radiol.
Sec. Artificial Intelligence in Radiology
Volume 5 - 2025 | doi: 10.3389/fradi.2025.1683149
This article is part of the Research TopicEmerging Fast Medical Imaging Techniques in RadiologyView all 6 articles
A Case series of 99mTc-MDP Bone Scintigraphy (Planar and SPECT CT) in Mucormycosis IN THE ERA OF COVID 19
Provisionally accepted
- All India Institute of Medical Sciences, Rishikesh, Rishikesh, India
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Mucormycosis is a serious fungal infection affecting immunocompromised individuals, caused by fungi from the Mucorales order, particularly Rhizopus species. It primarily spreads through inhalation of spores, with diabetes, cancers, organ transplants, immunosuppressive drugs, and COVID-19 being major risk factors. The infection manifests in various forms such as encephalic, cutaneous, gastrointestinal, pulmonary, and rhino cerebral, often leading to tissue necrosis and blood vessel invasion. Imaging diagnosis is aided by CT and MRI scans, while 99m Tc MDP bone scintigraphy has found to be a more accurate imaging tool to look for bone remodelling and erosive changes associated with invasive fungal sinusitis including mucormycosis. Treatment involves prompt surgical debridement and addressing the underlying immune deficiency. Here we present a series of cases where 99m Tc MDP bone scintigraphy played a key role in management of mucormycosis of the head. In conclusion, 99mTc MDP scintigraphy is a promising tool for evaluation, guiding diagnosis and management of mucormycosis.
Keywords: Bone scintigraphy, COVID-19, Mucormycosis, SPECT/CT, head and neck
Received: 10 Aug 2025; Accepted: 21 Oct 2025.
Copyright: © 2025 Dhingra, K, Kumar and Tyagi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Vandana Kumar Dhingra, modisbanu@yahoo.com
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