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ORIGINAL RESEARCH article

Front. Reprod. Health

Sec. Andrology

Volume 7 - 2025 | doi: 10.3389/frph.2025.1555597

Clinical observation of trans-urethral reconstruction of urethral meatus and navicularis fossa short strictures with annular inlay oral mucosa graft urethroplasty

Provisionally accepted
Zhenyu  LiZhenyu LiZhiguang  ZhaoZhiguang ZhaoGeng  ZhangGeng ZhangHe  WangHe WangBo  ZhangBo ZhangWei  ZhangWei Zhang*
  • Tangdu Hospital, Air Force Medical University, Xi'an, China

The final, formatted version of the article will be published soon.

Objective To explore the clinical efficacy and safety of an urethroplasty technique for fossa navicularis strictures using a transurethral annular inlay oral mucosa graft. Methods Retrospective analysis of the database collected clinical data of patients with urethral meatus and navicular fossa stricture who underwent transurethral reconstruction with annular inlay oral mucosa graft urethroplasty in Tangdu Hospital from July 2021 to October 2024. operation success defined as the ability to pass the F24 urethral probe, and the secondary outcome is the urinary flow rate and patient satisfaction at 1, 3, 6, and 12 months. Results All 12 patients successfully completed the surgery. The average age was (56.8 ± 6.8) years old and average length of urethral stricture was (1.6 ± 0.2) cm. 3 patients had a history of transurethral endoscopic surgery, 8 had penile Lichen Sclerosus (LS), and 1 had no obvious causes. Over a median follow-up of 19 months, the average maximum urinary flow rate was(21.2±3.2)ml/s at 3 months , the average maximum urinary flow rate (19.5 ± 4.2) ml/s at 12 months. One patient experienced urine pain with a thin stream and spraying urination after 3 months. physical examination of the urethral meatus opening scar was found, and the symptoms disappeared after urethral incision. The follow-up survey of sexual life after 1 year showed that 7 patients (58.3%) had successful life within 1 year compared with 2 patients (16.7%) before surgery. There were no cases of erectile dysfunction and poor wound healing. The patients were either very satisfied (75%) or satisfied (25%) with the operation. All patients would recommend urethroplasty to others. Conclusion Transurethral annular inlay oral mucosa urethroplasty for urethral meatus and navicular fossa stricture reconstruction is a safe, feasible, and effective surgical method, cosmetic effect of penis head. This technique has advantages in improving sexual function and better penis head cosmesis. 【Key words】 Urethral stricture;Navicular fossa;Oral mucosa;Urethroplasty;Annular inlay

Keywords: Urethral Stricture, Navicular fossa, oral mucosa, urethroplasty, Annular inlay

Received: 05 Jan 2025; Accepted: 14 Jul 2025.

Copyright: © 2025 Li, Zhao, Zhang, Wang, Zhang and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Wei Zhang, Tangdu Hospital, Air Force Medical University, Xi'an, China

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