REVIEW article
Front. Reprod. Health
Sec. Gynecology
Volume 7 - 2025 | doi: 10.3389/frph.2025.1608143
New Potential in the Treatment of Moderate to Severe Intrauterine Adhesions: Influencing Factors for Menstrual Improvement
Provisionally accepted
- First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China
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Background: This article reviews the research progress in recent years on the influencing factors for menstrual improvement in patients with moderate to severe intrauterine adhesions. To improve the treatment effect, reduce the risk of re-adhesion, optimize the treatment plan, enhance patients' quality of life, and prevent infertility and miscarriage. Objective: Identify the factors that may affect menstrual improvement in patients with moderate to severe intrauterine adhesions. Method: An in-depth literature search was carried out on four databases to sort out the research results on the influencing factors of menstrual improvement in patients with moderate to severe intrauterine adhesions from 2014 to 2024. Findings: The review incorporated 60 papers and found that the influencing factors for menstrual improvement in patients with moderate to severe intrauterine adhesions involve (1) the development of the Müllerian duct and the levels of anti-Müllerian hormone. (2) The interaction and dynamic changes between mesenchymal stem cells and the endocrine system. (3) The impact of hysteroscopic surgery on the endometrium and menstrual improvement, including the effects of the operation method, frequency of implementation, and postoperative management of hysteroscopic surgery. (4) The role of psychological factors. Discussion The results of this review highlight the factors influencing menstrual improvement in patients with moderate to severe intrauterine adhesions. However, the influencing factors of menstrual improvement are multifaceted and interrelated. Future research needs to further explore the interactions among these factors and how to optimize treatment plans to improve treatment outcomes.
Keywords: Intrauterine Adhesions(IUA), menstrual improvement, Hysteroscope, Mental Health, review, Women
Received: 08 Apr 2025; Accepted: 18 Aug 2025.
Copyright: © 2025 Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xinyue Zhang, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.