The Molecular Mechanisms of Chronic Inflammation Development

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Editorial

15 November 2012

The molecular mechanisms of chronic inflammation development

Masaaki Murakami

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Toshio Hirano

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84 citations

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Masaaki Murakami

Institute for Genetic Medicine, Hokkaido University

National Institutes for Quantum and Radiological Science and Technology (Japan)

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Inflammation is critical for the development of many complex diseases and disorders including autoimmune diseases, metabolic syndrome, neurodegenerative diseases, cancers, and cardiovascular diseases. Inflammation comes as two types: chronic inflammation, which can be defined as a dysregulated form of inflammation, and acute inflammation, which can defined as a regulated form. Because of its special role in the aforementioned diseases, establishing methods to control chronic inflammation is important for developing cures and treatments. One challenge for this purpose has been the ability to distinguish chronic and acute inflammation based on molecular biology diagnostics. Thus, this Research Topic is focused on articles that can shed some new light on the molecular mechanisms responsible for the development of chronic inflammation and its related conditions.

Inflammation is critical for the development of many complex diseases and disorders including autoimmune diseases, metabolic syndrome, neurodegenerative diseases, cancers, and cardiovascular diseases. Inflammation comes as two types: chronic inflammation, which can be defined as a dysregulated form of inflammation, and acute inflammation, which can defined as a regulated form. Because of its special role in the aforementioned diseases, establishing methods to control chronic inflammation is important for developing cures and treatments. One challenge for this purpose has been the ability to distinguish chronic and acute inflammation based on molecular biology diagnostics. Thus, this Research Topic is focused on articles that can shed some new light on the molecular mechanisms responsible for the development of chronic inflammation and its related conditions.

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Masaaki Murakami

Institute for Genetic Medicine, Hokkaido University

National Institutes for Quantum and Radiological Science and Technology (Japan)

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168,355 Total views

124,693 Article views

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5,376 Topic views

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Frontiers in Immunology

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