Aav8 | List of Frontiers open access articles

Original Research

Published on 11 Feb 2020

Cervical Gene Delivery of the Antimicrobial Peptide, Human β-Defensin (HBD)-3, in a Mouse Model of Ascending Infection-Related Preterm Birth

in Mucosal Immunity

Natalie Suff
Rajvinder Karda
Juan Antinao Diaz
Joanne Ng
Julien Baruteau
Dany Perocheau
Peter W. Taylor
Dagmar Alber
Suzanne M. K. Buckley
Mona Bajaj-Elliott

Frontiers in Immunology

doi 10.3389/fimmu.2020.00106

8,884 views
25 citations

Original Research

Published on 09 Jan 2024

Unlocking therapeutic potential: dual gene therapy for ameliorating the disease phenotypes in a mouse model of RPE65 Leber congenital amaurosis

in Ophthalmology

Yanbo Liu
Jingjie Tai
Chaofeng Yu
Dan Xu
Dan Xiao
Jijing Pang

Frontiers in Medicine

doi 10.3389/fmed.2023.1291795

3,823 views
5 citations

Original Research

Published on 31 Jan 2022

Chimeric Mice Engrafted With Canine Hepatocytes Exhibits Similar AAV Transduction Efficiency to Hemophilia B Dog

in Translational Pharmacology

Wenwei Shao
Junjiang Sun
Xiaojing Chen
Amanda Dobbins
Elizabeth P. Merricks
R. Jude Samulski
Timothy C. Nichols
Chengwen Li

Frontiers in Pharmacology

doi 10.3389/fphar.2022.815317

4,380 views
4 citations

Original Research

Published on 29 Feb 2024

AAV8 vector induced gliosis following neuronal transgene expression

in Translational Neuroscience

Faye McLeod
Elaine McDermott
Shermin Mak
Darren Walsh
Mark Turnbull
Fiona E. N. LeBeau
Andrew Jackson
Andrew J. Trevelyan
Gavin J. Clowry

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1287228

5,446 views
7 citations

Original Research

Published on 05 Aug 2022

Adeno-associated virus-mediated expression of activated factor V (FVa) for hemophilia phenotypic correction

in Hematology

Junjiang Sun
Xiaojing Chen
Zheng Chai
Hongqian Niu
Amanda L. Dobbins
Timothy C. Nichols
Chengwen Li

Frontiers in Medicine

doi 10.3389/fmed.2022.880763

4,144 views
2 citations

Mini Review

Published on 17 Mar 2021

Anti-AAV Antibodies in AAV Gene Therapy: Current Challenges and Possible Solutions

in Vaccines and Molecular Therapeutics

Thomas Weber

Frontiers in Immunology

doi 10.3389/fimmu.2021.658399

43,394 views
153 citations

Original Research

Published on 01 Oct 2024

An improved high-resolution method for quantitative separation of empty and filled AAV8 capsids by strong anion exchange HPLC

in Cell and Gene Therapy

Samantha Schrecke
Kevin McManus
Cassandra Moshfegh
Jessica Stone
Thuy-Uyen Nguyen
Gustavo Rivas
Ismaeel Muhamed
Daniel A. J. Mitchell

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2024.1436857

5,469 views
7 citations

Original Research

Published on 27 Apr 2023

Enhanced sensitivity of neutralizing antibody detection for different AAV serotypes using HeLa cells with overexpressed AAVR

in Experimental Pharmacology and Drug Discovery

Zhaoyue Zheng
Jingya Ye
Mi Leng
Chunmei Gan
Na Tang
Wei Li
C. Alexander Valencia
Biao Dong
Hoi Yee Chow

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1188290

6,128 views
12 citations

Brief Research Report

Published on 19 Jul 2023

Sustained heterologous gene expression in pancreatic islet organoids using adeno-associated virus serotype 8

in Cell and Gene Therapy

Anna Voznesenskaya
Per-Olof Berggren
Erwin Ilegems

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2023.1147244

3,806 views
3 citations

Original Research

Published on 15 Jun 2023

Promising AAV.U7snRNAs vectors targeting DMPK improve DM1 hallmarks in patient-derived cell lines

in Molecular and Cellular Pathology

Camila F. Almeida
Florence Robriquet
Tatyana A. Vetter
Nianyuan Huang
Reid Neinast
Lumariz Hernandez-Rosario
Dhanarajan Rajakumar
W. David Arnold
Kim L. McBride
Kevin M. Flanigan

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2023.1181040

8,800 views
4 citations

Brief Research Report

Published on 20 Dec 2023

Quantitative analysis of preferential utilization of AAV ITR as the packaging terminal signal

in Cell and Gene Therapy

Xin Li
Lohra Mickelle Miller
Matthew Chrzanowski
Jiahe Tian
Martin F. Jarrold
Roland W. Herzog
Weidong Xiao
Benjamin Draper
Junping Zhang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2023.1327433

8,517 views
9 citations

Original Research

Published on 23 Jun 2021

Liver-Directed AAV8 Booster Vaccine Expressing Plasmodium falciparum Antigen Following Adenovirus Vaccine Priming Elicits Sterile Protection in a Murine Model

in Vaccines and Molecular Therapeutics

Mohammad Shahnaij
Mitsuhiro Iyori
Hiroaki Mizukami
Mayu Kajino
Iroha Yamagoshi
Intan Syafira
Yenni Yusuf
Ken Fujiwara
Daisuke S. Yamamoto
Hirotomo Kato

Frontiers in Immunology

doi 10.3389/fimmu.2021.612910

8,870 views
15 citations

Original Research

Published on 27 Sep 2024

Seroprevalence of binding and neutralizing antibodies against 18 adeno-associated virus types in patients with neuromuscular disorders

in Viral Immunology

Xiaoyan Wang
Patrick Julian Klann
Ellen Wiedtke
Yumi Sano
Nico Fischer
Lisa Schiller
Anna Elfert
Anne-Katrin Güttsches
Ute Weyen
Dirk Grimm

Frontiers in Immunology

doi 10.3389/fimmu.2024.1450858

5,518 views
11 citations

Brief Research Report

Published on 31 Mar 2026

Fecal AAV8 shedding and co-housing reduces EAE disease severity: implications for preclinical study design

in Gene and Cell Therapy

Cristina D. Gaddie
Geoffrey D. Keeler

Frontiers in Medicine

doi 10.3389/fmed.2026.1810215

316 views

Original Research

Published on 26 Jun 2021

Inhibition of Hepatitis B Virus by AAV8-Derived CRISPR/SaCas9 Expressed From Liver-Specific Promoters

in Virology

Kun Yan
Jiangpeng Feng
Xing Liu
Hongyun Wang
Qiaohong Li
Jiali Li
Tianmo Xu
Muhammad Sajid
Hafiz Ullah
Li Zhou

Frontiers in Microbiology

doi 10.3389/fmicb.2021.665184

8,869 views
26 citations

Original Research

Published on 10 Feb 2017

Adeno-Associated Viral Vectors Serotype 8 for Cell-Specific Delivery of Therapeutic Genes in the Central Nervous System

Diego Pignataro
Diego Sucunza
Lucia Vanrell
Esperanza Lopez-Franco
Iria G. Dopeso-Reyes
Africa Vales
Mirja Hommel
Alberto J. Rico
Jose L. Lanciego
Gloria Gonzalez-Aseguinolaza

Frontiers in Neuroanatomy

doi 10.3389/fnana.2017.00002

15,656 views
42 citations

Articles

Cervical Gene Delivery of the Antimicrobial Peptide, Human β-Defensin (HBD)-3, in a Mouse Model of Ascending Infection-Related Preterm Birth

Unlocking therapeutic potential: dual gene therapy for ameliorating the disease phenotypes in a mouse model of RPE65 Leber congenital amaurosis

Chimeric Mice Engrafted With Canine Hepatocytes Exhibits Similar AAV Transduction Efficiency to Hemophilia B Dog

AAV8 vector induced gliosis following neuronal transgene expression

Adeno-associated virus-mediated expression of activated factor V (FVa) for hemophilia phenotypic correction

Anti-AAV Antibodies in AAV Gene Therapy: Current Challenges and Possible Solutions

An improved high-resolution method for quantitative separation of empty and filled AAV8 capsids by strong anion exchange HPLC

Enhanced sensitivity of neutralizing antibody detection for different AAV serotypes using HeLa cells with overexpressed AAVR

Sustained heterologous gene expression in pancreatic islet organoids using adeno-associated virus serotype 8

Promising AAV.U7snRNAs vectors targeting DMPK improve DM1 hallmarks in patient-derived cell lines

Quantitative analysis of preferential utilization of AAV ITR as the packaging terminal signal

Liver-Directed AAV8 Booster Vaccine Expressing Plasmodium falciparum Antigen Following Adenovirus Vaccine Priming Elicits Sterile Protection in a Murine Model

Seroprevalence of binding and neutralizing antibodies against 18 adeno-associated virus types in patients with neuromuscular disorders

Fecal AAV8 shedding and co-housing reduces EAE disease severity: implications for preclinical study design

Inhibition of Hepatitis B Virus by AAV8-Derived CRISPR/SaCas9 Expressed From Liver-Specific Promoters

Adeno-Associated Viral Vectors Serotype 8 for Cell-Specific Delivery of Therapeutic Genes in the Central Nervous System