Active Constituent | List of Frontiers open access articles

Review

Published on 25 Mar 2022

A Comprehensive Review on the Therapeutic Potential of Curcuma longa Linn. in Relation to its Major Active Constituent Curcumin

in Ethnopharmacology

Shivkanya Fuloria
Jyoti Mehta
Aditi Chandel
Mahendran Sekar
Nur Najihah Izzati Mat Rani
M. Yasmin Begum
Vetriselvan Subramaniyan
Kumarappan Chidambaram
Lakshmi Thangavelu
Rusli Nordin

Frontiers in Pharmacology

doi 10.3389/fphar.2022.820806

110,160 views
386 citations

Original Research

Published on 09 Feb 2023

Pterostilbene, an active constituent of blueberries, enhances innate immune activation and restricts enterovirus D68 infection

in Viral Immunology

Qingran Yang
Huili Li
Zhaoxue Li
Jiaxin Yang
Zhe Zhang
Lili Zhang
Haoran Guo
Wei Wei

Frontiers in Immunology

doi 10.3389/fimmu.2023.1118933

4,072 views
10 citations

Original Research

Published on 22 Oct 2019

Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux

in Experimental Pharmacology and Drug Discovery

Dong Wang
Haoran Guo
Huahong Yang
Dongyin Wang
Pujun Gao
Wei Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01238

8,674 views
33 citations

Review

Published on 10 Feb 2025

A comprehensive review of Schisandrin B’s preclinical antitumor activity and mechanistic insights from network pharmacology

in Pharmacology of Anti-Cancer Drugs

Yanhua Fang
Juan Pan
Piao Wang
Ruoyu Wang
Shanshan Liang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1528533

3,667 views
1 citation

Original Research

Published on 28 Jul 2021

Chronoeffects of the Herbal Medicines Puerariae radix and Coptidis rhizoma in Mice: A Potential Role of REV-ERBα

in Ethnopharmacology

Jinming Liu
Haiman Xu
Li Zhang
Shuai Wang
Danyi Lu
Min Chen
Baojian Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.707844

4,609 views
8 citations

Review

Published on 16 Jun 2023

Research progress of sophoridine’s pharmacological activities and its molecular mechanism: an updated review

in Ethnopharmacology

Yiwei Chen
Xiang Wang
Dongmei Ye
Zhousheng Yang
Qingrong Shen
Xiaoxia Liu
Chunxia Chen
Xiaoyu Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1126636

6,166 views
8 citations

Correction

Published on 13 Nov 2025

Correction: The active constituent of pine needle oil, bornyl acetate, suppresses NSCLC progression by inhibiting the PI3K/AKT/ABCB1 signaling axis

in Pharmacology of Anti-Cancer Drugs

Jieheng Wu
Jiaming Ren
Lu Wang
Zeyang Yang
Xuanyin Wang
Ziyi Tu
Xinlei Liu
Ye Wang
Yaxuan Cao
Xu Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1730938

651 views

Original Research

Published on 23 Sep 2025

The active constituent of pine needle oil, bornyl acetate, suppresses NSCLC progression by inhibiting the PI3K/AKT/ABCB1 signaling axis

in Pharmacology of Anti-Cancer Drugs

Jieheng Wu
Jiaming Ren
Lu Wang
Zeyang Yang
Xuanyin Wang
Ziyi Tu
Xinlei Liu
Ye Wang
Yaxuan Cao
Xu Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1653461

2,313 views

Original Research

Published on 04 Nov 2020

The Active Constituent From Gynostemma Pentaphyllum Prevents Liver Fibrosis Through Regulation of the TGF-β1/NDRG2/MAPK Axis

in Systems Biology Archive

Hui Huang
Kuifeng Wang
Qian Liu
Feihong Ji
Hu Zhou
Shanhua Fang
Jiansheng Zhu

Frontiers in Genetics

doi 10.3389/fgene.2020.594824

5,958 views
11 citations

Original Research

Published on 15 Sep 2025

The effects of clonal integration and earthworms on the growth, active constituent accumulation in Glechoma longituba, and the soil microbial community in its root zone

in Plant Symbiotic Interactions

Bing-Nan Zhao
Xiao-Gai Wang
Rui Zhang
Xue-Ge He
Zi-Yang Xie
Xiao-Qin Yao
Chao Si

Frontiers in Plant Science

doi 10.3389/fpls.2025.1596905

2,710 views
1 citation

Original Research

Published on 21 Jan 2016

Silibinin Regulates Lipid Metabolism and Differentiation in Functional Human Adipocytes

in Experimental Pharmacology and Drug Discovery

Ignazio Barbagallo
Luca Vanella
Maria T. Cambria
Daniele Tibullo
Justyna Godos
Laura Guarnaccia
Agata Zappalà
Fabio Galvano
Giovanni Li Volti

Frontiers in Pharmacology

doi 10.3389/fphar.2015.00309

7,195 views
38 citations

Review

Published on 19 Oct 2022

Bufadienolides originated from toad source and their anti-inflammatory activity

in Inflammation Pharmacology

Denglang Zou
Qiqi Wang
Tao Chen
Duocheng Sang
Tingqin Yang
Yuhan Wang
Mengze Gao
Fangfang He
Yulin Li
Liangliang He

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1044027

8,153 views
22 citations

Original Research

Published on 25 Feb 2022

Echinacoside Protects Dopaminergic Neurons Through Regulating IL-6/JAK2/STAT3 Pathway in Parkinson’s Disease Model

in Neuropharmacology

Xueping Yang
Qingyun Yv
Fanlong Ye
Sheng Chen
Zhang He
Wenwei Li
Fang Dong

Frontiers in Pharmacology

doi 10.3389/fphar.2022.848813

6,522 views
41 citations

Review

Published on 11 Oct 2022

Ginkgo biloba leaf extract EGb 761® as a paragon of the product by process concept

in Ethnopharmacology

Žarko Kulić
Martin D. Lehner
Gunnar P. H. Dietz

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1007746

20,200 views
38 citations

Review

Published on 27 Feb 2017

Plant Derived Phytocompound, Embelin in CNS Disorders: A Systematic Review

in Ethnopharmacology

Uday P. Kundap
Saatheeyavaane Bhuvanendran
Yatinesh Kumari
Iekhsan Othman
Mohd. Farooq Shaikh

Frontiers in Pharmacology

doi 10.3389/fphar.2017.00076

11,267 views
60 citations

Original Research

Published on 18 Apr 2023

Lycium barbarum polysaccharide alleviates dextran sodium sulfate-induced inflammatory bowel disease by regulating M1/M2 macrophage polarization via the STAT1 and STAT6 pathways

in Inflammation Pharmacology

Juan Wang
Huiying Gao
Yuan Xie
Peng Wang
Yu Li
Junli Zhao
Chunlin Wang
Xin Ma
Yuwen Wang
Qinwen Mao

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1044576

7,331 views
32 citations

Articles

A Comprehensive Review on the Therapeutic Potential of Curcuma longa Linn. in Relation to its Major Active Constituent Curcumin

Pterostilbene, an active constituent of blueberries, enhances innate immune activation and restricts enterovirus D68 infection

Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux

A comprehensive review of Schisandrin B’s preclinical antitumor activity and mechanistic insights from network pharmacology

Chronoeffects of the Herbal Medicines Puerariae radix and Coptidis rhizoma in Mice: A Potential Role of REV-ERBα

Research progress of sophoridine’s pharmacological activities and its molecular mechanism: an updated review

Correction: The active constituent of pine needle oil, bornyl acetate, suppresses NSCLC progression by inhibiting the PI3K/AKT/ABCB1 signaling axis

The active constituent of pine needle oil, bornyl acetate, suppresses NSCLC progression by inhibiting the PI3K/AKT/ABCB1 signaling axis

The Active Constituent From Gynostemma Pentaphyllum Prevents Liver Fibrosis Through Regulation of the TGF-β1/NDRG2/MAPK Axis

The effects of clonal integration and earthworms on the growth, active constituent accumulation in Glechoma longituba, and the soil microbial community in its root zone

Silibinin Regulates Lipid Metabolism and Differentiation in Functional Human Adipocytes

Bufadienolides originated from toad source and their anti-inflammatory activity

Echinacoside Protects Dopaminergic Neurons Through Regulating IL-6/JAK2/STAT3 Pathway in Parkinson’s Disease Model

Ginkgo biloba leaf extract EGb 761® as a paragon of the product by process concept

Plant Derived Phytocompound, Embelin in CNS Disorders: A Systematic Review

Lycium barbarum polysaccharide alleviates dextran sodium sulfate-induced inflammatory bowel disease by regulating M1/M2 macrophage polarization via the STAT1 and STAT6 pathways