And Sglt2 | List of Frontiers open access articles

Original Research

Published on 19 Jun 2024

CETP and SGLT2 inhibitor combination therapy increases glycemic control: a 2x2 factorial Mendelian randomization analysis

in Translational and Clinical Endocrinology

Bohdan B. Khomtchouk
Patrick Sun
Zane A. Maggio
Marc Ditmarsch
John J. P. Kastelein
Michael H. Davidson

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1359780

6,264 views
1 citation

Original Research

Published on 17 Nov 2022

Decreased expression of Glucagon-like peptide-1 receptor and Sodium-glucose co-transporter 2 in patients with proliferative diabetic retinopathy

in Clinical Diabetes

Hui Chen
Xiongze Zhang
Nanying Liao
Yuying Ji
Lan Mi
Yuhong Gan
Yongyue Su
Feng Wen

Frontiers in Endocrinology

doi 10.3389/fendo.2022.1020252

4,394 views
10 citations

Review

Published on 10 Oct 2023

Effects of GLP-1 agonists and SGLT2 inhibitors during pregnancy and lactation on offspring outcomes: a systematic review of the evidence

in Clinical Diabetes

Dion R. P. Muller
Dirk J. Stenvers
Arjan Malekzadeh
Frederik Holleman
Rebecca C. Painter
Sarah E. Siegelaar

Frontiers in Endocrinology

doi 10.3389/fendo.2023.1215356

53,762 views
126 citations

Review

Published on 16 Jan 2024

Exploring the clinical utility of DPP-IV and SGLT2 inhibitors in papillary thyroid cancer: a literature review

in Pharmacology of Anti-Cancer Drugs

Angelika Buczyńska
Maria Kościuszko
Adam Jacek Krętowski
Anna Popławska-Kita

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1323083

4,665 views
4 citations

Review

Published on 29 Oct 2025

Molecular mechanisms and computational insights into human SGLTs: advancing toward selective SGLT1 inhibition

in Structural Biology

Nadhiri Kaijage
Sebastian Kraszewski

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1668400

2,216 views
1 citation

Original Research

Published on 29 Sep 2025

Localization of the therapeutic targets for endothelin receptor antagonists and sodium-glucose co-transporter 2 inhibitors in the chronic liver disease, primary sclerosing cholangitis

in Translational Pharmacology

Rhoda E. Kuc
Anna L. Paterson
Thomas L. Williams
William T. H. Gelson
Peter J. Greasley
Phil Ambery
Janet J. Maguire
Anthony P. Davenport

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1680875

2,587 views

Original Research

Published on 10 Dec 2014

Use of systems pharmacology modeling to elucidate the operating characteristics of SGLT1 and SGLT2 in renal glucose reabsorption in humans

in Experimental Pharmacology and Drug Discovery

Yasong Lu
Steven C. Griffen
David W. Boulton
Tarek A. Leil

Frontiers in Pharmacology

doi 10.3389/fphar.2014.00274

12,990 views
48 citations

Original Research

Published on 08 Aug 2022

SGLT1/2 as the potential biomarkers of renal damage under Apoe−/− and chronic stress via the BP neural network model and support vector machine

in Cardiovascular Therapeutics

Gai-feng Hu
Xiang Wang
Ling-bing Meng
Jian-yi Li
Hong-xuan Xu
Di-shan Wu
Meng-jie Shan
Yu-hui Chen
Jia-pei Xu
Tao Gong

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2022.948909

3,588 views
4 citations

Original Research

Published on 23 Apr 2025

Dapagliflozin ameliorates intestinal stem cell aging by regulating the MAPK signaling pathway in Drosophila

in Stem Cell Research

Jinhua Yan
Chenxi Feng
Hanmei Zhang
Ting Luo
Haiyang Chen
Haiou Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1576258

3,854 views

Review

Published on 11 Aug 2021

Role of DPP-4 and SGLT2 Inhibitors Connected to Alzheimer Disease in Type 2 Diabetes Mellitus

in Neurodegeneration

A Young Sim
Sumit Barua
Jong Youl Kim
Yong-ho Lee
Jong Eun Lee

Frontiers in Neuroscience

doi 10.3389/fnins.2021.708547

15,226 views
56 citations

Case Report

Published on 31 May 2021

Case Report: Metreleptin and SGLT2 Inhibitor Combination Therapy Is Effective for Acquired Incomplete Lipodystrophy

in Obesity

Ayako Nagayama
Kenji Ashida
Miki Watanabe
Kanoko Moritaka
Aya Sonezaki
Yoichiro Kitajima
Hirokazu Takahashi
Satoko Yoshinobu
Shimpei Iwata
Junichi Yasuda

Frontiers in Endocrinology

doi 10.3389/fendo.2021.690996

7,158 views
8 citations

Review

Published on 12 Feb 2026

Beyond inflammation: metabolic implications of biological and TsDMARD therapies in dermatologic and rheumatologic diseases

in Inflammation

Salvatore Corrao
Salvatore Scibetta
Nicola Pardo
Ignazio Cangemi
Luigi Mirarchi
Giacomo Corrao
Simona Amodeo
Luigi Calvo

Frontiers in Immunology

doi 10.3389/fimmu.2026.1668159

654 views

Original Research

Published on 14 Oct 2022

Effect of metformin monotherapy and dual or triple concomitant therapy with metformin on glycemic control and lipid profile management of patients with type 2 diabetes mellitus

in Family Medicine and Primary Care

Yan-Yu Lin
Shuen-Fu Weng
Chung-Huei Hsu
Chen-Ling Huang
Yu-Pei Lin
Min-Chun Yeh
A-Young Han
Yu-Shan Hsieh

Frontiers in Medicine

doi 10.3389/fmed.2022.995944

8,376 views
14 citations

Original Research

Published on 18 May 2022

Understanding the Mechanism of Dysglycemia in a Fanconi-Bickel Syndrome Patient

in Diabetes: Molecular Mechanisms

Sanaa Sharari
Mustapha Aouida
Idris Mohammed
Basma Haris
Ajaz Ahmad Bhat
Iman Hawari
Sabah Nisar
Igor Pavlovski
Kabir H. Biswas
Najeeb Syed

Frontiers in Endocrinology

doi 10.3389/fendo.2022.841788

4,776 views
7 citations

Review

Published on 14 Jun 2024

Glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter 2 inhibitors, anti-diabetic drugs in heart failure and cognitive impairment: potential mechanisms of the protective effects

in Cardiovascular and Smooth Muscle Pharmacology

Maria Antonietta Riemma
Elena Mele
Maria Donniacuo
Marialucia Telesca
Gabriella Bellocchio
Giuseppe Castaldo
Francesco Rossi
Antonella De Angelis
Donato Cappetta
Konrad Urbanek

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1422740

6,737 views
7 citations

Review

Published on 08 Jul 2025

Immune inflammation and metabolic interactions in the pathogenesis of diabetic nephropathy

in Diabetes: Molecular Mechanisms

Guangjian Hou
Youzi Dong
Yuehua Jiang
Wenbo Zhao
Le Zhou
Shengnan Cao
Wei Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1602594

8,159 views
21 citations

Articles

CETP and SGLT2 inhibitor combination therapy increases glycemic control: a 2x2 factorial Mendelian randomization analysis

Decreased expression of Glucagon-like peptide-1 receptor and Sodium-glucose co-transporter 2 in patients with proliferative diabetic retinopathy

Effects of GLP-1 agonists and SGLT2 inhibitors during pregnancy and lactation on offspring outcomes: a systematic review of the evidence

Exploring the clinical utility of DPP-IV and SGLT2 inhibitors in papillary thyroid cancer: a literature review

Molecular mechanisms and computational insights into human SGLTs: advancing toward selective SGLT1 inhibition

Localization of the therapeutic targets for endothelin receptor antagonists and sodium-glucose co-transporter 2 inhibitors in the chronic liver disease, primary sclerosing cholangitis

Use of systems pharmacology modeling to elucidate the operating characteristics of SGLT1 and SGLT2 in renal glucose reabsorption in humans

SGLT1/2 as the potential biomarkers of renal damage under Apoe−/− and chronic stress via the BP neural network model and support vector machine

Dapagliflozin ameliorates intestinal stem cell aging by regulating the MAPK signaling pathway in Drosophila

Role of DPP-4 and SGLT2 Inhibitors Connected to Alzheimer Disease in Type 2 Diabetes Mellitus

Case Report: Metreleptin and SGLT2 Inhibitor Combination Therapy Is Effective for Acquired Incomplete Lipodystrophy

Beyond inflammation: metabolic implications of biological and TsDMARD therapies in dermatologic and rheumatologic diseases

Effect of metformin monotherapy and dual or triple concomitant therapy with metformin on glycemic control and lipid profile management of patients with type 2 diabetes mellitus

Understanding the Mechanism of Dysglycemia in a Fanconi-Bickel Syndrome Patient

Glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter 2 inhibitors, anti-diabetic drugs in heart failure and cognitive impairment: potential mechanisms of the protective effects

Immune inflammation and metabolic interactions in the pathogenesis of diabetic nephropathy