Apc Gene | List of Frontiers open access articles

Original Research

Published on 15 May 2025

Identification of shared neoantigens derived from frameshift mutations in the APC gene

in Cancer Immunity and Immunotherapy

Peng Zhao
Clara Effenberger
Saki Matsumoto
Toshihiro Tanaka
Yusuke Nakamura
Kazuma Kiyotani

Frontiers in Immunology

doi 10.3389/fimmu.2025.1574955

4,499 views
2 citations

Original Research

Published on 18 Jul 2023

T cell migration and effector function differences in familial adenomatous polyposis patients with APC gene mutations

in T Cell Biology

Céline Cuche
Marta Mastrogiovanni
Marie Juzans
Hélène Laude
Marie-Noëlle Ungeheuer
Daniel Krentzel
Maria Isabella Gariboldi
Daniel Scott-Algara
Marianne Madec
Sophie Goyard

Frontiers in Immunology

doi 10.3389/fimmu.2023.1163466

7,897 views
12 citations

Original Research

Published on 27 Jul 2023

Identification of a novel CNV at the APC gene in a Chinese family with familial adenomatous polyposis

in Molecular Diagnostics and Therapeutics

Juyi Li
Chengzhi He
Jing Gong
Xiufang Wang
Chao Liu
Aiping Deng
Lin Zhu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1234296

3,656 views
1 citation

Review

Published on 23 Apr 2021

APC Promoter Methylation in Gastrointestinal Cancer

in Cancer Genetics

Lila Zhu
Xinyu Li
Ying Yuan
Caixia Dong
Mengyuan Yang

Frontiers in Oncology

doi 10.3389/fonc.2021.653222

15,703 views
40 citations

Case Report

Published on 03 Aug 2023

A complex rearrangement between APC and TP63 associated with familial adenomatous polyposis identified by multimodal genomic analysis: a case report

in Cancer Genetics

Satoyo Oda
Mineko Ushiama
Wataru Nakamura
Masahiro Gotoh
Noriko Tanabe
Tomoko Watanabe
Yoko Odaka
Kazuhiko Aoyagi
Hiromi Sakamoto
Takeshi Nakajima

Frontiers in Oncology

doi 10.3389/fonc.2023.1205847

2,911 views
3 citations

Original Research

Published on 15 Oct 2025

The use of whole genome sequencing to study young patients with 100+ adenomas of the colon

in Cancer Genetics

Aleksey S. Tsukanov
Sergey I. Achkasov
Anna N. Loginova
Vitaly P. Shubin
Dmitry Y. Pikunov
Nikolay N. Chekanov
Anastasiya S. Salomatina
Konstantin V. Severinov

Frontiers in Oncology

doi 10.3389/fonc.2025.1616441

1,661 views
1 citation

Case Report

Published on 14 Mar 2024

Case report: Turcot syndrome type 2 in a developing country within the Caribbean

in Cancer Genetics

Melissa Daniel-Abdool
Brandon Griffith
Ute Bartels
Curt Bodkyn
Kevon Dindial

Frontiers in Oncology

doi 10.3389/fonc.2024.1331271

3,188 views
1 citation

Original Research

Published on 19 Dec 2018

Whole-Genome Sequencing Identifies a Novel Variation of WAS Gene Coordinating With Heterozygous Germline Mutation of APC to Enhance Hepatoblastoma Oncogenesis

in Predictive Toxicology and Exposomics

Li Zhang
Yaqiong Jin
Kai Zheng
Huanmin Wang
Shen Yang
Chenkai Lv
Wei Han
Yongbo Yu
Yeran Yang
Di Geng

Frontiers in Genetics

doi 10.3389/fgene.2018.00668

6,083 views
10 citations

Case Report

Published on 25 Mar 2021

Case Report: Coinheritance of Germline Mutations in APC and BRCA1 in Colorectal Cancer

in Molecular and Cellular Oncology

Wei Huang
Jin Bian
Xiaoping Qian
Lin Shao
Haiyan Li
Lu Zhang
Lin Wang

Frontiers in Oncology

doi 10.3389/fonc.2021.658389

6,272 views
7 citations

Case Report

Published on 04 Mar 2020

An APC Mutation in a Large Chinese Kindred With Familial Adenomatous Polyposis Was Identified Using Both Next Generation Sequencing and Simple STR Marker Haplotypes

in Genomic Medicine

Qitao Zhan
Liya Wang
Xiangrong Xu
Yan Sun
Lejun Li
Xuchen Qi
Feng Chen
Xiaoming Wei
Michael L. Raff
Ping Yu

Frontiers in Genetics

doi 10.3389/fgene.2020.00191

5,046 views
3 citations

Original Research

Published on 15 May 2025

Bispecific antibody targeting shared indel-derived neoantigen of APC

in Cancer Immunity and Immunotherapy

Clara Effenberger
Xiaojing Wu
Peng Zhao
Saki Matsumoto
Yusuke Nakamura
Kazuma Kiyotani

Frontiers in Immunology

doi 10.3389/fimmu.2025.1574958

4,067 views
1 citation

Original Research

Published on 27 Jun 2025

Investigating the link between APCI1307K mutation and breast cancer in a Jordanian Arab population

in Breast Cancer

Baha Sharaf
Hira Bani Hani
Anas Zayed
Maha Barbar
Suhaib Khater
Ahmad Hushki
Rashid Abdel-Razeq
Mohammad Titi
Reem Al-Halalsheh
Suleiman Mahafdah

Frontiers in Oncology

doi 10.3389/fonc.2025.1557341

1,701 views

Original Research

Published on 24 Jan 2022

Association Between Tumor Mutation Profile and Clinical Outcomes Among Hispanic-Latino Patients With Metastatic Colorectal Cancer

in Gastrointestinal Cancers: Colorectal Cancer

Alexander Philipovskiy
Reshad Ghafouri
Alok Kumar Dwivedi
Luis Alvarado
Richard McCallum
Felipe Maegawa
Ioannis T. Konstantinidis
Nawar Hakim
Scott Shurmur
Sanjay Awasthi

Frontiers in Oncology

doi 10.3389/fonc.2021.772225

4,971 views
8 citations

Original Research

Published on 19 Dec 2025

Early genetic events in the colorectal carcinogenic pathway of familial adenomatous polyposis and sporadic polyp: germline and somatic alterations in carcinogenesis

in Cancer Genetics and Oncogenomics

Hiroki Tanabe
Yusuke Mizukami
Yusuke Ono
Hidehiro Takei
Nobue Tamamura
Yu Kobayashi
Keitaro Takahashi
Katsuyoshi Ando
Nobuhiro Ueno
Shin Kashima

Frontiers in Genetics

doi 10.3389/fgene.2025.1668133

1,971 views

Original Research

Published on 10 Jun 2021

Genetic Characterization of Cancer of Unknown Primary Using Liquid Biopsy Approaches

in Molecular and Cellular Oncology

Noemi Laprovitera
Irene Salamon
Francesco Gelsomino
Elisa Porcellini
Mattia Riefolo
Marianna Garonzi
Paola Tononi
Sabrina Valente
Silvia Sabbioni
Francesca Fontana

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.666156

9,591 views
23 citations

Original Research

Published on 03 Jul 2024

Evolutionary history of adenomas to colorectal cancer in FAP families

in Cancer Genetics and Oncogenomics

Cuiping Yang
Enfei Xiang
Ping Chen
Xuqian Fang

Frontiers in Genetics

doi 10.3389/fgene.2024.1391851

4,782 views
6 citations

Articles

Identification of shared neoantigens derived from frameshift mutations in the APC gene

T cell migration and effector function differences in familial adenomatous polyposis patients with APC gene mutations

Identification of a novel CNV at the APC gene in a Chinese family with familial adenomatous polyposis

APC Promoter Methylation in Gastrointestinal Cancer

A complex rearrangement between APC and TP63 associated with familial adenomatous polyposis identified by multimodal genomic analysis: a case report

The use of whole genome sequencing to study young patients with 100+ adenomas of the colon

Case report: Turcot syndrome type 2 in a developing country within the Caribbean

Whole-Genome Sequencing Identifies a Novel Variation of WAS Gene Coordinating With Heterozygous Germline Mutation of APC to Enhance Hepatoblastoma Oncogenesis

Case Report: Coinheritance of Germline Mutations in APC and BRCA1 in Colorectal Cancer

An APC Mutation in a Large Chinese Kindred With Familial Adenomatous Polyposis Was Identified Using Both Next Generation Sequencing and Simple STR Marker Haplotypes

Bispecific antibody targeting shared indel-derived neoantigen of APC

Investigating the link between APCI1307K mutation and breast cancer in a Jordanian Arab population

Association Between Tumor Mutation Profile and Clinical Outcomes Among Hispanic-Latino Patients With Metastatic Colorectal Cancer

Early genetic events in the colorectal carcinogenic pathway of familial adenomatous polyposis and sporadic polyp: germline and somatic alterations in carcinogenesis

Genetic Characterization of Cancer of Unknown Primary Using Liquid Biopsy Approaches

Evolutionary history of adenomas to colorectal cancer in FAP families