Bladder Pain | List of Frontiers open access articles

Original Research

Published on 22 Apr 2026

Oral administration of kratom leaf extract alleviates anxiety-like behavior, urinary bladder pain, voiding dysfunction, and bladder hypercontractility via attenuating muscarinic receptor response in male mice exposed to chronic water avoidance stress

in Autonomic Neuroscience

Sarunnuch Sattayachiti
Panida Chumpong
Dania Cheaha
Nattapon Rotpenpian
Ekkasit Kumarnsit
Nipaporn Konthapakdee

Frontiers in Neuroscience

doi 10.3389/fnins.2026.1810337

853 views

Mini Review

Published on 15 May 2018

Potential of Endocannabinoids to Control Bladder Pain

Dale E. Bjorling
Zun-yi Wang

Frontiers in Systems Neuroscience

doi 10.3389/fnsys.2018.00017

6,901 views
20 citations

Original Research

Published on 11 Mar 2022

Neonatal Bladder Inflammation Results in Adult Female Mouse Phenotype With Increased Frequency and Nociceptive Responses to Bladder Filling

Buffie Clodfelder-Miller
Timothy J. Ness
Jennifer J. DeBerry

Frontiers in Systems Neuroscience

doi 10.3389/fnsys.2022.858220

5,553 views
1 citation

Original Research

Published on 25 Mar 2022

Defining Molecular Treatment Targets for Bladder Pain Syndrome/Interstitial Cystitis: Uncovering Adhesion Molecules

in Drugs Outcomes Research and Policies

Guldal Inal-Gultekin
Zeliha Gormez
Naside Mangir

Frontiers in Pharmacology

doi 10.3389/fphar.2022.780855

4,245 views
7 citations

Original Research

Published on 31 Oct 2025

Analysis of the diagnostic value of peripheral blood immune inflammatory indicators of female bladder pain syndrome

in Genitourinary Surgery and Interventions

Yinglei Wang
Shenglai Liu
Haonan Shi
Chunxiao Xie
Peng Li
Kaipeng Jia
Yang Tang
Hailong Hu

Frontiers in Surgery

doi 10.3389/fsurg.2025.1685098

1,561 views

Original Research

Published on 05 Nov 2021

Unsupervised Machine Learning Approaches Reveal Distinct Phenotypes of Perceived Bladder Pain: A Pilot Study

in Abdominal and Pelvic Pain

Patricia J. Mwesigwa
Nicholas J. Jackson
Ashley T. Caron
Falisha Kanji
James E. Ackerman
Jessica R. Webb
Victoria C. S. Scott
Karyn S. Eilber
David M. Underhill
Jennifer T. Anger

Frontiers in Pain Research

doi 10.3389/fpain.2021.757878

4,214 views
9 citations

Original Research

Published on 13 May 2022

Bladder Oxidative Stress and HMGB1 Release Contribute to PAR4-Mediated Bladder Pain in Mice

Shaojing Ye
Fei Ma
Dlovan F. D. Mahmood
Katherine L. Meyer-Siegler
Lin Leng
Richard Bucala
Pedro L. Vera

Frontiers in Systems Neuroscience

doi 10.3389/fnsys.2022.882493

6,463 views
6 citations

Mini Review

Published on 13 Feb 2014

Female reproductive tract pain: targets, challenges, and outcomes

in Neuropharmacology

Phillip Jobling
Kate O'Hara
Susan Hua

Frontiers in Pharmacology

doi 10.3389/fphar.2014.00017

33,229 views
17 citations

Original Research

Published on 12 Feb 2018

Differential Regulation of Bladder Pain and Voiding Function by Sensory Afferent Populations Revealed by Selective Optogenetic Activation

Jennifer J. DeBerry
Vijay K. Samineni
Bryan A. Copits
Christopher J. Sullivan
Sherri K. Vogt
Kathryn M. Albers
Brian M. Davis
Robert W. Gereau

Frontiers in Integrative Neuroscience

doi 10.3389/fnint.2018.00005

8,884 views
26 citations

Original Research

Published on 30 Aug 2021

Combined Signature of the Urinary Microbiome and Metabolome in Patients With Interstitial Cystitis

in Microbiome in Health and Disease

Hewei Xu
Nebiyu Elias Tamrat
Jie Gao
Jie Xu
Yiduo Zhou
Sicong Zhang
Zhengsen Chen
Yunpeng Shao
Liucheng Ding
Baixin Shen

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2021.711746

6,436 views
28 citations

Mini Review

Published on 01 Sep 2021

Peripheral, Central, and Cross Sensitization in Endometriosis-Associated Pain and Comorbid Pain Syndromes

in Gynecology

Helen C. McNamara
Helena C. Frawley
Jacqueline F. Donoghue
Emma Readman
Martin Healey
Lenore Ellett
Charlotte Reddington
Lauren J. Hicks
Keryn Harlow
Peter A. W. Rogers

Frontiers in Reproductive Health

doi 10.3389/frph.2021.729642

16,337 views
74 citations

Case Report

Published on 11 Dec 2018

Long-Term Relief of Painful Bladder Syndrome by High-Intensity, Low-Frequency Repetitive Transcranial Magnetic Stimulation of the Right and Left Dorsolateral Prefrontal Cortices

in Autonomic Neuroscience

Julien Nizard
Julien Esnault
Bénédicte Bouche
Alcira Suarez Moreno
Jean-Pascal Lefaucheur
Jean-Paul Nguyen

Frontiers in Neuroscience

doi 10.3389/fnins.2018.00925

5,998 views
21 citations

Original Research

Published on 28 Aug 2020

Characterization and Validation of a Chronic Model of Cyclophosphamide-Induced Interstitial Cystitis/Bladder Pain Syndrome in Rats

in Inflammation Pharmacology

Céline Augé
Xavier Gamé
Nathalie Vergnolle
Philippe Lluel
Sophie Chabot

Frontiers in Pharmacology

doi 10.3389/fphar.2020.01305

12,235 views
61 citations

Original Research

Published on 07 Nov 2013

Characterization of bladder sensory neurons in the context of myelination, receptors for pain modulators, and acute responses to bladder inflammation

in Autonomic Neuroscience

Shelley L Forrest
Peregrine B Osborne
Janet R Keast

Frontiers in Neuroscience

doi 10.3389/fnins.2013.00206

10,052 views
24 citations

Original Research

Published on 22 Dec 2022

TRPV4 activation prevents lipopolysaccharide-induced painful bladder hypersensitivity in rats by regulating immune pathways

in Molecular Innate Immunity

Masaru Yoshizumi
Naoya Tazawa
Chizuko Watanabe
Hirokazu Mizoguchi

Frontiers in Immunology

doi 10.3389/fimmu.2022.1080302

6,936 views
14 citations

Original Research

Published on 08 Mar 2023

Involvement of acid sensing ion channel (ASIC)-3 in an acute urinary bladder-colon cross sensitization model in rodent

in Abdominal and Pelvic Pain

Karim Atmani
Mathieu Meleine
Ludovic Langlois
Moïse Coëffier
Pablo Brumovsky
Anne-Marie Leroi
Guillaume Gourcerol

Frontiers in Pain Research

doi 10.3389/fpain.2023.1083514

3,095 views
1 citation

Articles

Oral administration of kratom leaf extract alleviates anxiety-like behavior, urinary bladder pain, voiding dysfunction, and bladder hypercontractility via attenuating muscarinic receptor response in male mice exposed to chronic water avoidance stress

Potential of Endocannabinoids to Control Bladder Pain

Neonatal Bladder Inflammation Results in Adult Female Mouse Phenotype With Increased Frequency and Nociceptive Responses to Bladder Filling

Defining Molecular Treatment Targets for Bladder Pain Syndrome/Interstitial Cystitis: Uncovering Adhesion Molecules

Analysis of the diagnostic value of peripheral blood immune inflammatory indicators of female bladder pain syndrome

Unsupervised Machine Learning Approaches Reveal Distinct Phenotypes of Perceived Bladder Pain: A Pilot Study

Bladder Oxidative Stress and HMGB1 Release Contribute to PAR4-Mediated Bladder Pain in Mice

Female reproductive tract pain: targets, challenges, and outcomes

Differential Regulation of Bladder Pain and Voiding Function by Sensory Afferent Populations Revealed by Selective Optogenetic Activation

Combined Signature of the Urinary Microbiome and Metabolome in Patients With Interstitial Cystitis

Peripheral, Central, and Cross Sensitization in Endometriosis-Associated Pain and Comorbid Pain Syndromes

Long-Term Relief of Painful Bladder Syndrome by High-Intensity, Low-Frequency Repetitive Transcranial Magnetic Stimulation of the Right and Left Dorsolateral Prefrontal Cortices

Characterization and Validation of a Chronic Model of Cyclophosphamide-Induced Interstitial Cystitis/Bladder Pain Syndrome in Rats

Characterization of bladder sensory neurons in the context of myelination, receptors for pain modulators, and acute responses to bladder inflammation

TRPV4 activation prevents lipopolysaccharide-induced painful bladder hypersensitivity in rats by regulating immune pathways

Involvement of acid sensing ion channel (ASIC)-3 in an acute urinary bladder-colon cross sensitization model in rodent