Bowel Movements | List of Frontiers open access articles

Original Research

Published on 10 Oct 2025

Efficacy of docusate in the treatment of constipation in pediatric patients

in General Pediatrics and Pediatric Emergency Care

Hamsah Saif
Tanay Maddula
Kerry Mendelsohn
Meredith Akerman
Nicole Sweeney
Estela Noyola
Gladys El-Chaar

Frontiers in Pediatrics

doi 10.3389/fped.2025.1652620

2,641 views

Clinical Trial

Accepted on 20 Feb 2026

Effects of Low-Dose Medium-Chain Triglycerides on Bowel Habit Outcomes in Japanese Adults Prone to Constipation: A Randomized, Double-Blind, LCT-Controlled Crossover Trial

in Clinical Nutrition

YUKI OTSUBO
HARUNA ISHIKAWA
Keiichi Kojima
Watanabe Shinji
Naohisa Nosaka
Tsuneo Matsuike

Frontiers in Nutrition

Original Research

Published on 27 Mar 2025

Open label study of a novel fiber product for bloating, gas, and bowel regularity

in Family Medicine and Primary Care

Alexander S. Ganz
Brooke Greeley
James Riggen
Aundria Riggen

Frontiers in Medicine

doi 10.3389/fmed.2025.1572261

43,184 views

Original Research

Published on 03 Sep 2025

Constipation symptoms are associated with worse cognitive outcomes in older adults without dementia

in Nutrition, Psychology and Brain Health

Xiaochang Liu
Juan Zhou
Xinyan Xie
Wenzhe Zheng
Dan Liu
Guirong Cheng
Feifei Hu
Junyi Wang
Cheng Cai
Jing Liu

Frontiers in Nutrition

doi 10.3389/fnut.2025.1578181

3,256 views

Original Research

Published on 31 Jul 2019

Independent and Interactive Effects of Habitually Ingesting Fermented Milk Products Containing Lactobacillus casei Strain Shirota and of Engaging in Moderate Habitual Daily Physical Activity on the Intestinal Health of Older People

in Food Microbiology

Yukitoshi Aoyagi
Ryuta Amamoto
Sungjin Park
Yusuke Honda
Kazuhito Shimamoto
Akira Kushiro
Hirokazu Tsuji
Hoshitaka Matsumoto
Kensuke Shimizu
Kouji Miyazaki

Frontiers in Microbiology

doi 10.3389/fmicb.2019.01477

22,676 views
40 citations

Case Report

Published on 17 Jul 2025

Secukinumab-induced Crohn’s disease in a psoriasis patient: a case report highlighting paradoxical reactions to IL-17 inhibition

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Huiling Dai
Chenyi Xu
Yehuang Wang
Kunlan Wu
Yang Zhang
Hao Ge
Yanlan Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1628461

4,010 views
2 citations

Original Research

Published on 23 Jan 2025

Efficacy of Tui Na in idiopathic constipation in children with cerebral palsy: a randomized controlled clinical trial

in Pediatric Gastroenterology, Hepatology and Nutrition

Huijuan Wang
Bichan Chen
Qian Long
Qiuping Yang
Jiawen Mao
Qinghua Ma
Xingqian Yi
Ying Wang
Yinghan Liu
Zhiliang Cao

Frontiers in Pediatrics

doi 10.3389/fped.2024.1503591

3,413 views
1 citation

Mini Review

Published on 20 Jan 2021

Functional Constipation and the Gut Microbiome in Children: Preclinical and Clinical Evidence

in Pediatric Gastroenterology, Hepatology and Nutrition

David Avelar Rodriguez
Jelena Popov
Elyanne M. Ratcliffe
Erick Manuel Toro Monjaraz

Frontiers in Pediatrics

doi 10.3389/fped.2020.595531

21,178 views
44 citations

Original Research

Published on 29 Nov 2023

Kale improves bowel movements in constipated women and affects some intestinal microbes and metabolites: a pilot study

in Nutrition and Microbes

Yuichiro Nishimoto
Felix Salim
Yohsuke Yamauchi
Yuka Mori
Shinnosuke Murakami
Asahi Suzuki
Shinji Fukuda
Takuji Yamada

Frontiers in Nutrition

doi 10.3389/fnut.2023.1247683

14,101 views
3 citations

Clinical Trial

Published on 12 Jul 2024

Microbiome-gut-brain axis contributes to patients and Bama miniature pigs with acute large ischemic stroke

in Gut-Brain Axis

Dazhi Deng
Hehua Lei
Zheng Cao
Cui Zhang
Ruichen Du
Xin Gao
Junjie Wei
Yibo Lu
Xiangzhen Zhou
Limin Zhang

Frontiers in Neuroscience

doi 10.3389/fnins.2024.1378844

3,565 views
2 citations

Original Research

Published on 05 Aug 2025

Clinical mechanisms of repetitive transcranial magnetic stimulation in improving constipation in Parkinson’s disease patients through the gut-brain axis

in Parkinson’s Disease and Aging-related Movement Disorders

Qianlan Bo
Yanmin Li
Xiayue Wang
Huijun Wang
Huimiao Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1607791

2,671 views
1 citation

Clinical Trial

Published on 04 Dec 2025

The effectiveness of Zhi-Shi plaster acupoint therapy combined with lactulose in the treatment of geriatrics functional constipation: a randomized controlled trial

in Experimental Therapeutics

Ying Wang
XiXia Zhang
XueFei Ding
Hui Li
JunQuan Xia
MengYan Zhou
YongZhi Hua
KeXuan Wu
LongShu Zhang
LiRong Zhou

Frontiers in Neurology

doi 10.3389/fneur.2025.1580163

1,028 views

Clinical Trial

Published on 01 Sep 2023

Effects of acupuncture on gut microbiota and short-chain fatty acids in patients with functional constipation: a randomized placebo-controlled trial

in Gastrointestinal and Hepatic Pharmacology

Xiang-Yun Yan
Jun-Peng Yao
Yan-Qiu Li
Xian-Jun Xiao
Wan-Qing Yang
Si-Jue Chen
Tai-Chun Tang
Yu-Qing Yang
Liu Qu
Yu-Jun Hou

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1223742

10,377 views
15 citations

Original Research

Published on 04 Nov 2022

Slow, deep breathing intervention improved symptoms and altered rectal sensitivity in patients with constipation-predominant irritable bowel syndrome

in Gut-Brain Axis

Jie Liu
Chaolan Lv
Wei Wang
Yizhou Huang
Bo Wang
Jiashuang Tian
Chenyu Sun
Yue Yu

Frontiers in Neuroscience

doi 10.3389/fnins.2022.1034547

14,103 views
18 citations

Original Research

Published on 14 Oct 2021

Microbial Profiles of Patients With Antipsychotic-Related Constipation Treated With Electroacupuncture

in Gastroenterology

Yuanjia Zheng
Xiumin Jiang
Yacen Gao
Lexin Yuan
Xiaotong Wang
Shengwei Wu
Yucen Xia
Lin Yao
Jinglan Yan
Lanying Liu

Frontiers in Medicine

doi 10.3389/fmed.2021.737713

5,490 views
12 citations

Review

Published on 21 Aug 2018

Ileal Bile Acid Transporter Inhibition for the Treatment of Chronic Constipation, Cholestatic Pruritus, and NASH

in Drug Metabolism and Transport

Samer Al-Dury
Hanns-Ulrich Marschall

Frontiers in Pharmacology

doi 10.3389/fphar.2018.00931

26,158 views
91 citations

Articles

Efficacy of docusate in the treatment of constipation in pediatric patients

Effects of Low-Dose Medium-Chain Triglycerides on Bowel Habit Outcomes in Japanese Adults Prone to Constipation: A Randomized, Double-Blind, LCT-Controlled Crossover Trial

Open label study of a novel fiber product for bloating, gas, and bowel regularity

Constipation symptoms are associated with worse cognitive outcomes in older adults without dementia

Independent and Interactive Effects of Habitually Ingesting Fermented Milk Products Containing Lactobacillus casei Strain Shirota and of Engaging in Moderate Habitual Daily Physical Activity on the Intestinal Health of Older People

Secukinumab-induced Crohn’s disease in a psoriasis patient: a case report highlighting paradoxical reactions to IL-17 inhibition

Efficacy of Tui Na in idiopathic constipation in children with cerebral palsy: a randomized controlled clinical trial

Functional Constipation and the Gut Microbiome in Children: Preclinical and Clinical Evidence

Kale improves bowel movements in constipated women and affects some intestinal microbes and metabolites: a pilot study

Microbiome-gut-brain axis contributes to patients and Bama miniature pigs with acute large ischemic stroke

Clinical mechanisms of repetitive transcranial magnetic stimulation in improving constipation in Parkinson’s disease patients through the gut-brain axis

The effectiveness of Zhi-Shi plaster acupoint therapy combined with lactulose in the treatment of geriatrics functional constipation: a randomized controlled trial

Effects of acupuncture on gut microbiota and short-chain fatty acids in patients with functional constipation: a randomized placebo-controlled trial

Slow, deep breathing intervention improved symptoms and altered rectal sensitivity in patients with constipation-predominant irritable bowel syndrome

Microbial Profiles of Patients With Antipsychotic-Related Constipation Treated With Electroacupuncture

Ileal Bile Acid Transporter Inhibition for the Treatment of Chronic Constipation, Cholestatic Pruritus, and NASH