Brca2 Mutation | List of Frontiers open access articles

Systematic Review

Published on 28 Oct 2021

BRCA1 Versus BRCA2 and PARP Inhibitors Efficacy in Solid Tumors:A Meta-Analysis of Randomized Controlled Trials

in Cancer Molecular Targets and Therapeutics

Shan Li
Li Tao
Haiyun Dai
Xue Gong
Yuguo Zhuo
Hui Xiang
Yueyang Zhao
Qing Gao
Liang Deng

Frontiers in Oncology

doi 10.3389/fonc.2021.718871

7,220 views
14 citations

Systematic Review

Published on 10 Jan 2022

Cost-Effectiveness Analysis of Imaging Modalities for Breast Cancer Surveillance Among BRCA1/2 Mutation Carriers: A Systematic Review

in Breast Cancer

Jiaxin Li
Ziqi Jia
Menglu Zhang
Gang Liu
Zeyu Xing
Xin Wang
Xin Huang
Kexin Feng
Jiang Wu
Wenyan Wang

Frontiers in Oncology

doi 10.3389/fonc.2021.763161

4,922 views
4 citations

Original Research

Published on 06 Mar 2020

Pioneering Informed Consent for Return of Research Results to Breast Cancer Patients Facing Barriers to Implementation of Genomic Medicine: The Kenyan BRCA1/2 Testing Experience Using Whole Exome Sequencing

in ELSI in Science and Genetics

Rispah Torrorey-Sawe
Nicole van der Merwe
Simeon Kipkoech Mining
Maritha J. Kotze

Frontiers in Genetics

doi 10.3389/fgene.2020.00170

7,894 views
16 citations

Case Report

Published on 19 Sep 2024

BRCA2 mutations in familial breast cancer with prostate cancer: a case report and literature review

in Breast Cancer

Zhengsheng Liu
Qianhao Huang
Meixuan Ding

Frontiers in Oncology

doi 10.3389/fonc.2024.1428849

3,509 views
4 citations

Case Report

Published on 16 May 2023

BRCA2 mutation in advanced lung squamous cell carcinoma treated with Olaparib and a PD-1 inhibitor: a case report

in Thoracic Oncology

Zhujun Chen
Kang Wang
Lintao Zhao
Liang Gong

Frontiers in Oncology

doi 10.3389/fonc.2023.1190100

7,391 views
8 citations

Original Research

Published on 21 Aug 2018

BRCA1 and BRCA2 Mutations Other Than the Founder Alleles Among Ashkenazi Jewish in the Population of Argentina

in Cancer Genetics

Angela R. Solano
Natalia C. Liria
Fernanda S. Jalil
Daniela M. Faggionato
Pablo G. Mele
Alejandra Mampel
Florencia C. Cardoso
Ernesto J. Podesta

Frontiers in Oncology

doi 10.3389/fonc.2018.00323

10,468 views
15 citations

Original Research

Published on 21 Oct 2021

Which Clinicopathologic Parameters Suggest Primary Resistance to Palbociclib in Combination With Letrozole as the First-Line Treatment for Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer?

in Breast Cancer

Ji-Yeon Kim
Jung Min Oh
Yeon Hee Park
Jin Seok Ahn
Young-Hyuck Im

Frontiers in Oncology

doi 10.3389/fonc.2021.759150

5,529 views
13 citations

Original Research

Published on 12 Aug 2021

Identification of BRCA2 Cis Double Heterozygous Breast Cancer Cases Using Whole Exome Sequencing: Phenotypic Expression and Impact on Personalized Oncology

in Cancer Genetics and Oncogenomics

Yosr Hamdi
Maroua Boujemaa
Najah Mighri
Nesrine Mejri
Olfa Jaidane
Sonia Ben Nasr
Hanen Bouaziz
Jamel Ben Hassouna
Aref Zribi
Yossra Berrazaga

Frontiers in Genetics

doi 10.3389/fgene.2021.674990

6,715 views
3 citations

Original Research

Published on 06 Jun 2022

Germline Mutations in Patients With Early-Onset Prostate Cancer

in Genitourinary Oncology

Tang Tang
Xintao Tan
Ze Wang
Shuo Wang
Yapeng Wang
Jing Xu
Xiajie Wei
Dianzheng Zhang
Qiuli Liu
Jun Jiang

Frontiers in Oncology

doi 10.3389/fonc.2022.826778

6,005 views
9 citations

Original Research

Published on 07 May 2021

Distinct Genomic Landscape of Colorectal Mucinous Carcinoma Determined via Comprehensive Genomic Profiling: Steps to a New Treatment Strategy

in Molecular and Cellular Oncology

Liang Huang
Shuanglin Luo
Xingwei Zhang
Yonghua Cai
Fangqin Xue
Huanxin Hu
Ziwei Zeng
Tengjiao Lin
Fei Wang
Weifeng Wang

Frontiers in Oncology

doi 10.3389/fonc.2021.603564

8,090 views
8 citations

Case Report

Published on 14 Feb 2022

Case Report: A BRCA2 Mutation Identified Through Next-Generation Sequencing in a Birt–Hogg–Dubè Syndrome Family

in Cancer Genetics

Erika Bandini
Ilaria Cangini
Valentina Arcangeli
Mila Ravegnani
Virginia Andreotti
Giovanna Prisinzano
Lorenza Pastorino
Giovanni Martinelli
Fabio Falcini
Daniele Calistri

Frontiers in Oncology

doi 10.3389/fonc.2022.835346

4,658 views
1 citation

Case Report

Published on 28 Jan 2026

Case Report: Individualized circulating tumor DNA monitoring guides olaparib adjuvant therapy: an early-stage breast cancer case with somatic BRCA2 mutation

in Breast Cancer

Qiuting You
Longlong Gong
Yi Chen
Xiaoxiao Dinglin
Ziliang Cheng
Qian Xia
Jinxia Xie
Jianli Zhao
Fengxi Su

Frontiers in Oncology

doi 10.3389/fonc.2026.1679086

664 views

Review

Published on 10 Feb 2022

Three-Dimensional Modelling of Ovarian Cancer: From Cell Lines to Organoids for Discovery and Personalized Medicine

in Cell and Gene Therapy

Christine Yee
Kristie-Ann Dickson
Mohammed N. Muntasir
Yue Ma
Deborah J. Marsh

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.836984

30,154 views
52 citations

Case Report

Published on 19 Dec 2025

Case Report: Deep and durable response to talazoparib in germline BRCA2-mutated rectal neuroendocrine carcinoma

in Gastrointestinal Cancers: Colorectal Cancer

Milan Khealani
Byoung Uk Park
Robben Schat
Emmanuel S. Antonarakis
Arjun Gupta

Frontiers in Oncology

doi 10.3389/fonc.2025.1705579

1,321 views

Systematic Review

Published on 07 Mar 2024

A systematic review of primary large cell neuroendocrine carcinoma of the prostate

in Genitourinary Oncology

Ngan Nguyen
Ronald Dean Franz
Omar Mohammed
Richard Huynh
Christine Kim Son
Rida Nusrat Khan
Bilawal Ahmed

Frontiers in Oncology

doi 10.3389/fonc.2024.1341794

5,536 views
13 citations

Original Research

Published on 16 Nov 2022

Potential value of the homologous recombination deficiency signature we developed in the prognosis and drug sensitivity of gastric cancer

in Computational Genomics

Xin Wu
Qiong Wang
Peifa Liu
Linde Sun
Yu Wang

Frontiers in Genetics

doi 10.3389/fgene.2022.1026871

6,012 views
12 citations

Articles

BRCA1 Versus BRCA2 and PARP Inhibitors Efficacy in Solid Tumors:A Meta-Analysis of Randomized Controlled Trials

Cost-Effectiveness Analysis of Imaging Modalities for Breast Cancer Surveillance Among BRCA1/2 Mutation Carriers: A Systematic Review

Pioneering Informed Consent for Return of Research Results to Breast Cancer Patients Facing Barriers to Implementation of Genomic Medicine: The Kenyan BRCA1/2 Testing Experience Using Whole Exome Sequencing

BRCA2 mutations in familial breast cancer with prostate cancer: a case report and literature review

BRCA2 mutation in advanced lung squamous cell carcinoma treated with Olaparib and a PD-1 inhibitor: a case report

BRCA1 and BRCA2 Mutations Other Than the Founder Alleles Among Ashkenazi Jewish in the Population of Argentina

Which Clinicopathologic Parameters Suggest Primary Resistance to Palbociclib in Combination With Letrozole as the First-Line Treatment for Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer?

Identification of BRCA2 Cis Double Heterozygous Breast Cancer Cases Using Whole Exome Sequencing: Phenotypic Expression and Impact on Personalized Oncology

Germline Mutations in Patients With Early-Onset Prostate Cancer

Distinct Genomic Landscape of Colorectal Mucinous Carcinoma Determined via Comprehensive Genomic Profiling: Steps to a New Treatment Strategy

Case Report: A BRCA2 Mutation Identified Through Next-Generation Sequencing in a Birt–Hogg–Dubè Syndrome Family

Case Report: Individualized circulating tumor DNA monitoring guides olaparib adjuvant therapy: an early-stage breast cancer case with somatic BRCA2 mutation

Three-Dimensional Modelling of Ovarian Cancer: From Cell Lines to Organoids for Discovery and Personalized Medicine

Case Report: Deep and durable response to talazoparib in germline BRCA2-mutated rectal neuroendocrine carcinoma

A systematic review of primary large cell neuroendocrine carcinoma of the prostate

Potential value of the homologous recombination deficiency signature we developed in the prognosis and drug sensitivity of gastric cancer